Berlin Institute for Medical Systems Biology
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Intronless homing: site-specific endonuclease SegF of bacteriophage T4 mediates localized marker exclusion analogous to homing endonucleases of group I introns.
Genes & development Feb, 2002 | Pubmed ID: 11825876
Two self-splicing group I introns in the ribonucleotide reductase large subunit gene of Staphylococcus aureus phage Twort.
Nucleic acids research May, 2002 | Pubmed ID: 11972330
The nicking homing endonuclease I-BasI is encoded by a group I intron in the DNA polymerase gene of the Bacillus thuringiensis phage Bastille.
Nucleic acids research Jun, 2003 | Pubmed ID: 12799434
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing.
RNA (New York, N.Y.) Mar, 2004 | Pubmed ID: 14970398
Group I intron homing in Bacillus phages SPO1 and SP82: a gene conversion event initiated by a nicking homing endonuclease.
Journal of bacteriology Jul, 2004 | Pubmed ID: 15205433
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Molecular cell Jul, 2004 | Pubmed ID: 15260970
DNA binding and cleavage by the HNH homing endonuclease I-HmuI.
Journal of molecular biology Sep, 2004 | Pubmed ID: 15313606
The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis.
Current biology : CB Dec, 2004 | Pubmed ID: 15589161
Endogenous MHC class II processing of a viral nuclear antigen after autophagy.
Science (New York, N.Y.) Jan, 2005 | Pubmed ID: 15591165
Retrotransposition strategies of the Lactococcus lactis Ll.LtrB group II intron are dictated by host identity and cellular environment.
Molecular microbiology Apr, 2005 | Pubmed ID: 15813740
Identification of novel argonaute-associated proteins.
Current biology : CB Dec, 2005 | Pubmed ID: 16289642
I-BasI and I-HmuI: two phage intron-encoded endonucleases with homologous DNA recognition sequences but distinct DNA specificities.
Journal of molecular biology May, 2006 | Pubmed ID: 16569414
SiRNA-mediated selective inhibition of mutant keratin mRNAs responsible for the skin disorder pachyonychia congenita.
Annals of the New York Academy of Sciences Oct, 2006 | Pubmed ID: 17145926
A mammalian microRNA expression atlas based on small RNA library sequencing.
Cell Jun, 2007 | Pubmed ID: 17604727
Cellular cofactors affecting hepatitis C virus infection and replication.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17616579
Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs.
RNA (New York, N.Y.) Dec, 2008 | Pubmed ID: 18978028
DGCR8-dependent microRNA biogenesis is essential for skin development.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2009 | Pubmed ID: 19114655
Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets.
Genome research Nov, 2009 | Pubmed ID: 19767416
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
Cell Apr, 2010 | Pubmed ID: 20371350
Chaperones get RISC loaded.
Molecular cell Jul, 2010 | Pubmed ID: 20670883
Fluorescence cross-correlation spectroscopy reveals mechanistic insights into the effect of 2'-O-methyl modified siRNAs in living cells.
Biophysical journal Jun, 2011 | Pubmed ID: 21689532
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
Molecular cell Aug, 2011 | Pubmed ID: 21723171
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells.
Nature cell biology Sep, 2011 | Pubmed ID: 21804543
doRiNA: a database of RNA interactions in post-transcriptional regulation.
Nucleic acids research Jan, 2012 | Pubmed ID: 22086949
Transcriptome-wide analysis of protein-RNA interactions using high-throughput sequencing.
Seminars in cell & developmental biology Dec, 2011 | Pubmed ID: 22212136
Markus Hafner1,
Markus Landthaler2,
Lukas Burger3,
Mohsen Khorshid3,
Jean Hausser4,
Philipp Berninger4,
Andrea Rothballer1,
Manuel Ascano1,
Anna-Carina Jungkamp2,
Mathias Munschauer2,
Alexander Ulrich1,
Greg S. Wardle1,
Scott Dewell5,
Mihaela Zavolan3,
Thomas Tuschl1
1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University,
2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine,
3, Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB),
4, Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB),
5Genomics Resource Center, Rockefeller University
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