Department of Developmental Biology
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Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.
Genes & development Apr, 2002 | Pubmed ID: 11937493
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.
Genes & development Jun, 2002 | Pubmed ID: 12080084
Ataxia and paroxysmal dyskinesia in mice lacking axonally transported FGF14.
Neuron Jul, 2002 | Pubmed ID: 12123606
Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.
The Journal of biological chemistry Oct, 2002 | Pubmed ID: 12145306
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.
Developmental cell Sep, 2002 | Pubmed ID: 12361605
Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains.
Development (Cambridge, England) Jan, 2003 | Pubmed ID: 12441294
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity.
Cell Jan, 2003 | Pubmed ID: 12553906
Fibroblast growth factor receptor 3 signaling regulates the onset of oligodendrocyte terminal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2003 | Pubmed ID: 12574417
Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.
Human molecular genetics Apr, 2003 | Pubmed ID: 12651873
A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2003 | Pubmed ID: 12702769
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth.
Development (Cambridge, England) Jul, 2003 | Pubmed ID: 12756187
Expression and function of FGF10 in mammalian inner ear development.
Developmental dynamics : an official publication of the American Association of Anatomists Jun, 2003 | Pubmed ID: 12761848
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs.
The Journal of biological chemistry Sep, 2003 | Pubmed ID: 12815063
Defective bone mineralization and osteopenia in young adult FGFR3-/- mice.
Human molecular genetics Feb, 2004 | Pubmed ID: 14681299
Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development.
Bone Jan, 2004 | Pubmed ID: 14751559
A twist code determines the onset of osteoblast differentiation.
Developmental cell Mar, 2004 | Pubmed ID: 15030764
Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15073186
Conserved roles for Slit and Robo proteins in midline commissural axon guidance.
Neuron Apr, 2004 | Pubmed ID: 15091338
Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.
Development (Cambridge, England) Aug, 2004 | Pubmed ID: 15229180
FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain.
Cell Jul, 2004 | Pubmed ID: 15260994
Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice.
Hearing research Aug, 2004 | Pubmed ID: 15276677
Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions.
Developmental biology Sep, 2004 | Pubmed ID: 15328018
Evolution of the Fgf and Fgfr gene families.
Trends in genetics : TIG Nov, 2004 | Pubmed ID: 15475116
Sequential roles of Hedgehog and Wnt signaling in osteoblast development.
Development (Cambridge, England) Jan, 2005 | Pubmed ID: 15576404
Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio.
Developmental biology Dec, 2004 | Pubmed ID: 15581873
Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo.
Developmental cell Jan, 2005 | Pubmed ID: 15621532
Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation.
American journal of human genetics Feb, 2005 | Pubmed ID: 15625620
Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation.
Developmental dynamics : an official publication of the American Association of Anatomists Jun, 2005 | Pubmed ID: 15778993
FGF signaling in the developing endochondral skeleton.
Cytokine & growth factor reviews Apr, 2005 | Pubmed ID: 15863035
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.
Development (Cambridge, England) Aug, 2005 | Pubmed ID: 15975938
Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23.
Endocrinology Nov, 2005 | Pubmed ID: 16081635
Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels.
The Journal of physiology Nov, 2005 | Pubmed ID: 16166153
Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development.
Development (Cambridge, England) Jan, 2006 | Pubmed ID: 16308329
Inhibition or activation of Apert syndrome FGFR2 (S252W) signaling by specific glycosaminoglycans.
The Journal of biological chemistry Mar, 2006 | Pubmed ID: 16373332
Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development.
Brain research May, 2006 | Pubmed ID: 16529728
FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains.
Development (Cambridge, England) Apr, 2006 | Pubmed ID: 16540513
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
The Journal of biological chemistry Jun, 2006 | Pubmed ID: 16597617
Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti.
Electrophoresis Apr, 2006 | Pubmed ID: 16609936
Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development.
Genes & development Jun, 2006 | Pubmed ID: 16778080
Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.
Developmental biology Aug, 2006 | Pubmed ID: 16815385
FGF signalling generates ventral telencephalic cells independently of SHH.
Development (Cambridge, England) Aug, 2006 | Pubmed ID: 16818446
A model for the pharmacological treatment of crouzon syndrome.
Neurosurgery Jul, 2006 | Pubmed ID: 16823318
Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.
Development (Cambridge, England) Sep, 2006 | Pubmed ID: 16887829
FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.
Developmental biology Feb, 2007 | Pubmed ID: 17014841
Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium.
Genes & development Nov, 2006 | Pubmed ID: 17050674
Heparan and chondroitin sulfate on growth plate perlecan mediate binding and delivery of FGF-2 to FGF receptors.
Matrix biology : journal of the International Society for Matrix Biology Apr, 2007 | Pubmed ID: 17169545
Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14.
Molecular and cellular neurosciences Mar, 2007 | Pubmed ID: 17208450
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis.
Development (Cambridge, England) Feb, 2007 | Pubmed ID: 17215304
Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14.
Neurobiology of disease Apr, 2007 | Pubmed ID: 17236779
Rebuilding the coronary vasculature: hedgehog as a new candidate for pharmacologic revascularization.
Trends in cardiovascular medicine Apr, 2007 | Pubmed ID: 17418368
FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.
Developmental biology Jul, 2007 | Pubmed ID: 17544391
Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17606897
Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels.
Neuron Aug, 2007 | Pubmed ID: 17678857
Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2007 | Pubmed ID: 17687036
FGF9 and SHH regulate mesenchymal Vegfa expression and development of the pulmonary capillary network.
Development (Cambridge, England) Oct, 2007 | Pubmed ID: 17881491
The FGF14(F145S) mutation disrupts the interaction of FGF14 with voltage-gated Na+ channels and impairs neuronal excitability.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2007 | Pubmed ID: 17978045
Fibroblast growth factors and Hedgehogs: at the heart of the epicardial signaling center.
Trends in genetics : TIG Jan, 2008 | Pubmed ID: 18054407
Functional evolutionary history of the mouse Fgf gene family.
Developmental dynamics : an official publication of the American Association of Anatomists Jan, 2008 | Pubmed ID: 18058912
FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis.
Development (Cambridge, England) Feb, 2008 | Pubmed ID: 18094024
Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members.
BMC evolutionary biology , 2008 | Pubmed ID: 18254951
Novel tool to suppress cell proliferation in vivo demonstrates that myocardial and coronary vascular growth represent distinct developmental programs.
Developmental dynamics : an official publication of the American Association of Anatomists Mar, 2008 | Pubmed ID: 18297725
Role of Fgf receptor 2c in adipocyte hypertrophy in mesenteric white adipose tissue.
Molecular and cellular endocrinology Jun, 2008 | Pubmed ID: 18396371
Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation.
Developmental biology Jun, 2008 | Pubmed ID: 18455718
An FGF-WNT gene regulatory network controls lung mesenchyme development.
Developmental biology Jul, 2008 | Pubmed ID: 18533146
Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.
The Journal of clinical investigation Jul, 2008 | Pubmed ID: 18568073
Fgf9 signaling regulates small intestinal elongation and mesenchymal development.
Development (Cambridge, England) Sep, 2008 | Pubmed ID: 18653563
Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development.
Development (Cambridge, England) Sep, 2008 | Pubmed ID: 18725519
FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons.
Neurobiology of disease Jan, 2009 | Pubmed ID: 18930825
Shared circuitry: developmental signaling cascades regulate both embryonic and adult coronary vasculature.
Circulation research Jan, 2009 | Pubmed ID: 19179669
FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.
Nature genetics Mar, 2009 | Pubmed ID: 19219044
Fibroblast growth factor expression during skeletal fracture healing in mice.
Developmental dynamics : an official publication of the American Association of Anatomists Mar, 2009 | Pubmed ID: 19235733
Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels.
The Journal of biological chemistry Jun, 2009 | Pubmed ID: 19406745
FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.
Molecular and cellular neurosciences Oct, 2009 | Pubmed ID: 19465131
Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix.
Molecular and cellular biology Sep, 2009 | Pubmed ID: 19564416
Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20133659
Healing of non-displaced fractures produced by fatigue loading of the mouse ulna.
Bone Jun, 2010 | Pubmed ID: 20215063
Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.
Development (Cambridge, England) Apr, 2010 | Pubmed ID: 20215350
Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis.
The Journal of cell biology Mar, 2010 | Pubmed ID: 20308431
Regulation of cellular calcium in vestibular supporting cells by otopetrin 1.
Journal of neurophysiology Dec, 2010 | Pubmed ID: 20554841
In vitro effects of recombinant otoconin 90 upon calcite crystal growth. Significance of tertiary structure.
Hearing research Sep, 2010 | Pubmed ID: 20595020
FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice.
Gastroenterology Oct, 2010 | Pubmed ID: 20603121
Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease.
Journal of biochemistry Feb, 2011 | Pubmed ID: 20940169
Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells.
Molecular and cellular neurosciences Mar, 2011 | Pubmed ID: 21236346
Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses.
BMC evolutionary biology , 2011 | Pubmed ID: 21261979
Histomorphological study of palatal shelf elevation during murine secondary palate formation.
Developmental dynamics : an official publication of the American Association of Anatomists Jul, 2011 | Pubmed ID: 21618642
Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development.
Development (Cambridge, England) Aug, 2011 | Pubmed ID: 21750028
FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium.
Development (Cambridge, England) Aug, 2011 | Pubmed ID: 21750042
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal.
PLoS biology Jan, 2012 | Pubmed ID: 22235191
Signaling networks regulating development of the lower respiratory tract.
Cold Spring Harbor perspectives in biology May, 2012 | Pubmed ID: 22550231
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.
Developmental cell Jun, 2012 | Pubmed ID: 22698282
Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling.
Development (Cambridge, England) Sep, 2012 | Pubmed ID: 22833125
Genomic landscape of non-small cell lung cancer in smokers and never-smokers.
Cell Sep, 2012 | Pubmed ID: 22980976
FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin.
Journal of cell science Dec, 2012 | Pubmed ID: 22992463
Development of the endochondral skeleton.
Cold Spring Harbor perspectives in biology Jan, 2013 | Pubmed ID: 23284041
Delineating a conserved genetic cassette promoting outgrowth of body appendages.
PLoS genetics , 2013 | Pubmed ID: 23358455
Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles.
Genes & development Feb, 2013 | Pubmed ID: 23431057
Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding.
Nature medicine Jul, 2013 | Pubmed ID: 23727932
Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3.
Cancer research Sep, 2013 | Pubmed ID: 23867472
FGF14 localization and organization of the axon initial segment.
Molecular and cellular neurosciences Sep, 2013 | Pubmed ID: 23891806
Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy.
PloS one , 2013 | Pubmed ID: 24349409
Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice.
PloS one , 2014 | Pubmed ID: 24454809
In vitro calcite crystal morphology is modulated by otoconial proteins otolin-1 and otoconin-90.
PloS one , 2014 | Pubmed ID: 24748133
FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands.
Development (Cambridge, England) Jul, 2014 | Pubmed ID: 24924191
Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin.
American journal of respiratory cell and molecular biology Jan, 2015 | Pubmed ID: 24988442
Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo.
PloS one , 2014 | Pubmed ID: 25093726
Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2014 | Pubmed ID: 25139991
OVOL2 is a critical regulator of ER71/ETV2 in generating FLK1+, hematopoietic, and endothelial cells from embryonic stem cells.
Blood Nov, 2014 | Pubmed ID: 25267199
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25349429
Characterization of the cell of origin and propagation potential of the fibroblast growth factor 9-induced mouse model of lung adenocarcinoma.
The Journal of pathology Mar, 2015 | Pubmed ID: 25413587
Fibroblast growth factor 2 is an essential cardioprotective factor in a closed-chest model of cardiac ischemia-reperfusion injury.
Physiological reports Jan, 2015 | Pubmed ID: 25626875
Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.
Developmental biology Apr, 2015 | Pubmed ID: 25678108
The Fibroblast Growth Factor signaling pathway.
Wiley interdisciplinary reviews. Developmental biology May-Jun, 2015 | Pubmed ID: 25772309
Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling.
eLife , 2015 | Pubmed ID: 25915623
Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2015 | Pubmed ID: 25926453
Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma.
PLoS genetics May, 2015 | Pubmed ID: 25978641
Fibroblast growth factor signaling in skeletal development and disease.
Genes & development Jul, 2015 | Pubmed ID: 26220993
Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation.
Developmental dynamics : an official publication of the American Association of Anatomists Nov, 2015 | Pubmed ID: 26250517
Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2016 | Pubmed ID: 26586661
Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development.
Cell reports Jan, 2016 | Pubmed ID: 26725121
Endothelial fibroblast growth factor receptor signaling is required for vascular remodeling following cardiac ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology Mar, 2016 | Pubmed ID: 26747503
A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development.
Developmental biology Mar, 2016 | Pubmed ID: 26794256
Proteomic analysis of native cerebellar iFGF14 complexes.
Channels (Austin, Tex.) Feb, 2016 | Pubmed ID: 26889602
Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival.
Scientific reports , 2016 | Pubmed ID: 26987296
Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
Journal of pharmaceutical sciences Apr, 2016 | Pubmed ID: 27019961
FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth.
Development (Cambridge, England) Apr, 2016 | Pubmed ID: 27052727
Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody.
Disease models & mechanisms May, 2016 | Pubmed ID: 27056048
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