Antonis K. Hatzopoulos

Participation of bone marrow-derived cells in long-term repair processes after experimental stroke.

Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis.

Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.

Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia.

Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase.

Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro.

Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.

Expression of the protein related to Dan and Cerberus gene--prdc--During eye, pharyngeal arch, somite, and swim bladder development in zebrafish.

The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.

Platelet-induced differentiation of endothelial progenitor cells.

Biologic properties of endothelial progenitor cells and their potential for cell therapy.

Adenosine receptor-mediated adhesion of endothelial progenitors to cardiac microvascular endothelial cells.

Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.

B-Raf-mediated signaling pathway regulates T cell development.

Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection.

Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.

T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix.

Cardiac repair and regeneration: the Rubik's cube of cell therapy for heart disease.

Stem cell therapy for cardiac repair: benefits and barriers.

Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction.

The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.

NF kappaB activation in embryonic endothelial progenitor cells enhances neovascularization via PSGL-1 mediated recruitment: novel role for LL37.

Stem cell therapy: pieces of the puzzle.

Adriamycin nephropathy: a failure of endothelial progenitor cell-induced repair.

Thymosin beta4: a key factor for protective effects of eEPCs in acute and chronic ischemia.

Intramyocardial injection of autologous bone marrow mononuclear cells for patients with chronic ischemic heart disease and left ventricular dysfunction (First Mononuclear Cells injected in the US [FOCUS]): Rationale and design.

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction.

Time is like a clock in my heart: implications for stem cell delivery after myocardial infarction.

Neuregulin-1β regulation of embryonic endothelial progenitor cell survival.

Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition.

Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.

Preconditioned endothelial progenitor cells reduce formation of melanoma metastases through SPARC-driven cell-cell interactions and endocytosis.

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.

Continuous antagonism by Dkk1 counter activates canonical Wnt signaling and promotes cardiomyocyte differentiation of embryonic stem cells.

Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.

Programmatic change: lung disease research in the era of induced pluripotency.

Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial.

Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.

Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation.

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure: The FOCUS-CCTRN Trial.

Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.

Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis.

Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.

Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm.

SDF-1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization.

Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.

Endothelial progenitor cells augment collateralization and hemodynamic rescue in a model of chronic cerebral ischemia.

Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis.

Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis.

Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension.