Porfirio Nava

The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells.

Tight junctions, from tight intercellular seals to sophisticated protein complexes involved in drug delivery, pathogens interaction and cell proliferation.

Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium.

JAM-A regulates permeability and inflammation in the intestine in vivo.

Formyl peptide receptor-1 activation enhances intestinal epithelial cell restitution through phosphatidylinositol 3-kinase-dependent activation of Rac1 and Cdc42.

Role of the intestinal barrier in inflammatory bowel disease.

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.

Pathophysiology of nasal polyposis: the role of desmosomal junctions.

Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization.

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells.

Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways.

Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling.

JAM-A regulates epithelial proliferation through Akt/β-catenin signalling.

The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.

Characterization of full-length and proteolytic cleavage fragments of desmoglein-2 in native human colon and colonic epithelial cell lines.

Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis.

Quorum-sensing systems LuxS/autoinducer 2 and Com regulate Streptococcus pneumoniae biofilms in a bioreactor with living cultures of human respiratory cells.

Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion.

Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis.

IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ.

Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier.

Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways.

Experimental Colitis Is Attenuated by Cardioprotective Diet Supplementation That Reduces Oxidative Stress, Inflammation, and Mucosal Damage.

The CpAL system regulates changes of the trans-epithelial resistance of human enterocytes during Clostridium perfringens type C infection.

Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility.

The pro-inflammatory cytokines IFNγ/TNFα increase chromogranin A-positive neuroendocrine cells in the colonic epithelium.