Department of Molecular and Cell Biology
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Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells.
The International journal of developmental biology Mar, 2002 | Pubmed ID: 11934148
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Development (Cambridge, England) May, 2002 | Pubmed ID: 11973276
Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research.
Diabetes Jul, 2002 | Pubmed ID: 12086925
"Stemness": transcriptional profiling of embryonic and adult stem cells.
Science (New York, N.Y.) Oct, 2002 | Pubmed ID: 12228720
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
Mechanisms of development Jan, 2003 | Pubmed ID: 12490294
Insulin staining of ES cell progeny from insulin uptake.
Science (New York, N.Y.) Jan, 2003 | Pubmed ID: 12532008
Single-cell transcript analysis of pancreas development.
Developmental cell Mar, 2003 | Pubmed ID: 12636919
Endothelial signaling during development.
Nature medicine Jun, 2003 | Pubmed ID: 12778164
Role of VEGF-A in vascularization of pancreatic islets.
Current biology : CB Jun, 2003 | Pubmed ID: 12814555
Genes, signals, and lineages in pancreas development.
Annual review of cell and developmental biology , 2003 | Pubmed ID: 14570564
Notch signaling controls multiple steps of pancreatic differentiation.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2003 | Pubmed ID: 14657333
Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Development (Cambridge, England) Jan, 2004 | Pubmed ID: 14660441
Derivation of embryonic stem-cell lines from human blastocysts.
The New England journal of medicine Mar, 2004 | Pubmed ID: 14999088
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.
Nature May, 2004 | Pubmed ID: 15129273
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15148312
How important are adult stem cells for tissue maintenance?
Cell cycle (Georgetown, Tex.) Sep, 2004 | Pubmed ID: 15326371
Altered nuclear transfer in stem-cell research - a flawed proposal.
The New England journal of medicine Dec, 2004 | Pubmed ID: 15625329
The molecular biography of the cell.
Cell Mar, 2005 | Pubmed ID: 15797372
Direct regulation of intestinal fate by Notch.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2005 | Pubmed ID: 16107537
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells.
Science (New York, N.Y.) Aug, 2005 | Pubmed ID: 16123299
Core transcriptional regulatory circuitry in human embryonic stem cells.
Cell Sep, 2005 | Pubmed ID: 16153702
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.
Cancer cell Sep, 2005 | Pubmed ID: 16169464
Beta-catenin is essential for pancreatic acinar but not islet development.
Development (Cambridge, England) Nov, 2005 | Pubmed ID: 16192304
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.
Developmental cell Mar, 2006 | Pubmed ID: 16516842
Control of developmental regulators by Polycomb in human embryonic stem cells.
Cell Apr, 2006 | Pubmed ID: 16630818
Reversal of type 1 diabetes in mice.
The New England journal of medicine Jul, 2006 | Pubmed ID: 16823003
Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.
Mechanisms of development Feb, 2007 | Pubmed ID: 17196797
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.
Nature Feb, 2007 | Pubmed ID: 17259975
Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Developmental biology Apr, 2007 | Pubmed ID: 17328885
A multipotent progenitor domain guides pancreatic organogenesis.
Developmental cell Jul, 2007 | Pubmed ID: 17609113
Recovery from diabetes in mice by beta cell regeneration.
The Journal of clinical investigation Sep, 2007 | Pubmed ID: 17786244
A gene regulatory network in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17940043
Genetic targeting of the endoderm with claudin-6CreER.
Developmental dynamics : an official publication of the American Association of Anatomists Feb, 2008 | Pubmed ID: 18213590
Facultative endocrine progenitor cells in the adult pancreas.
Cell Jan, 2008 | Pubmed ID: 18243094
Marked differences in differentiation propensity among human embryonic stem cell lines.
Nature biotechnology Mar, 2008 | Pubmed ID: 18278034
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.
Development (Cambridge, England) May, 2008 | Pubmed ID: 18367557
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Nature biotechnology Jul, 2008 | Pubmed ID: 18568017
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Nature Oct, 2008 | Pubmed ID: 18754011
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Nature biotechnology Nov, 2008 | Pubmed ID: 18849973
Extreme makeover: converting one cell into another.
Cell stem cell Oct, 2008 | Pubmed ID: 18940730
Transcriptional dynamics of endodermal organ formation.
Developmental dynamics : an official publication of the American Association of Anatomists Jan, 2009 | Pubmed ID: 19097184
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell stem cell Feb, 2009 | Pubmed ID: 19200798
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
Cell stem cell Apr, 2009 | Pubmed ID: 19341624
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.
Development (Cambridge, England) May, 2009 | Pubmed ID: 19369400
Generation of pluripotent stem cells from patients with type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2009 | Pubmed ID: 19720998
How to make beta cells?
Current opinion in cell biology Dec, 2009 | Pubmed ID: 19781928
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.
Genes & development Feb, 2010 | Pubmed ID: 20123909
Wnt signaling specifies and patterns intestinal endoderm.
Mechanisms of development Sep, 2011 | Pubmed ID: 21854845
Reprogramming within hours following nuclear transfer into mouse but not human zygotes.
Nature communications , 2011 | Pubmed ID: 21971503
Impracticality of egg donor recruitment in the absence of compensation.
Cell stem cell Oct, 2011 | Pubmed ID: 21982228
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