Department of Molecular and Biomedical Pharmacology
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Site-specific detection of DNA methylation utilizing mCpG-SEER.
Journal of the American Chemical Society Aug, 2006 | Pubmed ID: 16866532
Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18541537
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Bioorganic & medicinal chemistry letters Jul, 2009 | Pubmed ID: 19457665
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19828810
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain.
Molecular neurodegeneration , 2009 | Pubmed ID: 19889229
Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures.
Neuroscience letters Jan, 2010 | Pubmed ID: 20026181
NFATs and Alzheimer's Disease.
Molecular and cellular pharmacology Jan, 2010 | Pubmed ID: 20401186
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.
ACS chemical biology Oct, 2010 | Pubmed ID: 20681584
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Journal of the American Chemical Society Aug, 2010 | Pubmed ID: 20681585
A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death.
Chemical communications (Cambridge, England) Jan, 2011 | Pubmed ID: 20830433
Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2.
Chemical communications (Cambridge, England) Nov, 2010 | Pubmed ID: 20856941
Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.
Journal of the American Chemical Society Aug, 2011 | Pubmed ID: 21520929
Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.
Analytical chemistry Sep, 2011 | Pubmed ID: 21797230
Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats.
PloS one , 2012 | Pubmed ID: 22666474
Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2012 | Pubmed ID: 23152597
A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli.
Biochemistry Mar, 2013 | Pubmed ID: 23379331
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.
Journal of the American Chemical Society Jun, 2014 | Pubmed ID: 24846839
Calcineurin and glial signaling: neuroinflammation and beyond.
Journal of neuroinflammation , 2014 | Pubmed ID: 25199950
Proteopathic tau seeding predicts tauopathy in vivo.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2014 | Pubmed ID: 25261551
Early engineering approaches to improve peptide developability and manufacturability.
The AAPS journal Jan, 2015 | Pubmed ID: 25338742
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