Jennifer L. Furman

Site-specific detection of DNA methylation utilizing mCpG-SEER.

Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain.

Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures.

NFATs and Alzheimer's Disease.

A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.

Toward a general approach for RNA-templated hierarchical assembly of split-proteins.

A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death.

Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2.

Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.

Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats.

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.

A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli.

A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.

Calcineurin and glial signaling: neuroinflammation and beyond.

Proteopathic tau seeding predicts tauopathy in vivo.

Early engineering approaches to improve peptide developability and manufacturability.