Department of Medicine
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Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
Research in microbiology May, 2002 | Pubmed ID: 12066895
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast.
Genome research Aug, 2002 | Pubmed ID: 12176923
Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics.
Antimicrobial agents and chemotherapy Nov, 2002 | Pubmed ID: 12384335
Identification and characterization of a diamide sensitive mutant of Mycobacterium smegmatis.
FEMS microbiology letters Mar, 2003 | Pubmed ID: 12670676
Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.
Microbiology (Reading, England) May, 2003 | Pubmed ID: 12724395
The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA).
Journal of bacteriology Jun, 2003 | Pubmed ID: 12754249
The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold.
The Journal of biological chemistry Nov, 2003 | Pubmed ID: 12958317
Kinome analysis of host response to mycobacterial infection: a novel technique in proteomics.
Infection and immunity Oct, 2003 | Pubmed ID: 14500469
Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.
Biochemistry Oct, 2003 | Pubmed ID: 14556638
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.
Molecular microbiology Feb, 2004 | Pubmed ID: 14763976
Development of a liposome formulation of ethambutol.
Antimicrobial agents and chemotherapy May, 2004 | Pubmed ID: 15105152
The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo.
Molecular microbiology Jun, 2004 | Pubmed ID: 15186418
Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein.
Journal of bacteriology Sep, 2004 | Pubmed ID: 15342574
Screening of Compounds Toxicity against Human Monocytic cell line-THP-1 by Flow Cytometry.
Biological procedures online , 2004 | Pubmed ID: 15472722
Thiol specific oxidative stress response in Mycobacteria.
FEMS microbiology letters Aug, 2005 | Pubmed ID: 16006064
Mycobacterial manipulation of the host cell.
FEMS microbiology reviews Nov, 2005 | Pubmed ID: 16040149
Deletion of the Mycobacterium tuberculosis pknH gene confers a higher bacillary load during the chronic phase of infection in BALB/c mice.
Journal of bacteriology Aug, 2005 | Pubmed ID: 16077122
Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16210638
In vitro properties of antimicrobial bromotyrosine alkaloids.
Journal of medical microbiology Apr, 2006 | Pubmed ID: 16533988
Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme.
Protein expression and purification Jun, 2006 | Pubmed ID: 16630724
Mycothiol-dependent mycobacterial response to oxidative stress.
FEBS letters May, 2006 | Pubmed ID: 16643903
Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD.
Biochemical and biophysical research communications Sep, 2006 | Pubmed ID: 16879801
Mycobacterium avium subsp. paratuberculosis PtpA is an endogenous tyrosine phosphatase secreted during infection.
Infection and immunity Dec, 2006 | Pubmed ID: 16982836
Mycothiol-dependent proteins in actinomycetes.
FEMS microbiology reviews Apr, 2007 | Pubmed ID: 17286835
Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase.
Biochemical and biophysical research communications Mar, 2007 | Pubmed ID: 17286964
Innate protection of Mycobacterium smegmatis against the antimicrobial activity of nitric oxide is provided by mycothiol.
Antimicrobial agents and chemotherapy Sep, 2007 | Pubmed ID: 17638697
Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation.
Journal of cell science Aug, 2007 | Pubmed ID: 17652161
Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.
Biochemical and biophysical research communications Nov, 2007 | Pubmed ID: 17826740
Mycobacterium bovis bacillus Calmette-Guérin secreting active cathepsin S stimulates expression of mature MHC class II molecules and antigen presentation in human macrophages.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2007 | Pubmed ID: 17911599
Mycobacterium smegmatis biofilm formation and sliding motility are affected by the serine/threonine protein kinase PknF.
FEMS microbiology letters Jan, 2008 | Pubmed ID: 18031532
Molecular cloning and biochemical characterization of a serine threonine protein kinase, PknL, from Mycobacterium tuberculosis.
Protein expression and purification Apr, 2008 | Pubmed ID: 18276158
Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B.
Cell host & microbe May, 2008 | Pubmed ID: 18474358
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
Molecular microbiology Sep, 2008 | Pubmed ID: 18651841
Gaseous nitric oxide bactericidal activity retained during intermittent high-dose short duration exposure.
Nitric oxide : biology and chemistry Feb, 2009 | Pubmed ID: 18789393
The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection.
FEMS microbiology letters Jun, 2009 | Pubmed ID: 19341393
Mycobacterium tuberculosis PtkA is a novel protein tyrosine kinase whose substrate is PtpA.
The Biochemical journal May, 2009 | Pubmed ID: 19366344
Glutathione disulfide and S-nitrosoglutathione detoxification by Mycobacterium tuberculosis thioredoxin system.
FEBS letters Oct, 2009 | Pubmed ID: 19737561
Protein kinase and phosphatase signaling in Mycobacterium tuberculosis physiology and pathogenesis.
Biochimica et biophysica acta Mar, 2010 | Pubmed ID: 19766738
Slow release of nitric oxide from charged catheters and its effect on biofilm formation by Escherichia coli.
Antimicrobial agents and chemotherapy Jan, 2010 | Pubmed ID: 19884372
Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis.
BMC microbiology , 2010 | Pubmed ID: 20167072
Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles.
Nanomedicine : nanotechnology, biology, and medicine Oct, 2010 | Pubmed ID: 20215045
Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth.
Bioorganic & medicinal chemistry Jun, 2010 | Pubmed ID: 20462762
Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis.
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20630871
Antimycobacterial activity of UDP-galactopyranose mutase inhibitors.
International journal of antimicrobial agents Oct, 2010 | Pubmed ID: 20678902
MmpS4 promotes glycopeptidolipids biosynthesis and export in Mycobacterium smegmatis.
Molecular microbiology Nov, 2010 | Pubmed ID: 21062372
Antibacterial and cytotoxic activities of the sesquiterpene lactones cnicin and onopordopicrin.
Natural product communications Feb, 2011 | Pubmed ID: 21425665
Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis.
Antimicrobial agents and chemotherapy Jul, 2011 | Pubmed ID: 21502624
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.
Antimicrobial agents and chemotherapy Aug, 2011 | Pubmed ID: 21576426
Antimicrobial, anti-inflammatory, antiparasitic, and cytotoxic activities of Galium mexicanum.
Journal of ethnopharmacology Sep, 2011 | Pubmed ID: 21586319
Coresistance to isoniazid and ethionamide maps to mycothiol biosynthetic genes in Mycobacterium bovis.
Antimicrobial agents and chemotherapy Sep, 2011 | Pubmed ID: 21709101
Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles.
Nanomedicine : nanotechnology, biology, and medicine Apr, 2012 | Pubmed ID: 21718674
Comparative efficacy of commercially available and emerging antimicrobial urinary catheters against bacteriuria caused by E. coli in vitro.
Urology Aug, 2011 | Pubmed ID: 21820571
Antimicrobial activities of sesquiterpene lactones and inositol derivatives from Hymenoxys robusta.
Phytochemistry Dec, 2011 | Pubmed ID: 21963130
The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance.
The Journal of biological chemistry Jan, 2012 | Pubmed ID: 22069311
Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22087003
A phase I clinical study of inhaled nitric oxide in healthy adults.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jul, 2012 | Pubmed ID: 22520076
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.
PLoS pathogens , 2012 | Pubmed ID: 22589723
Antimicrobial, anti-inflammatory, antiparasitic, and cytotoxic activities of Laennecia confusa.
TheScientificWorldJournal , 2012 | Pubmed ID: 22623891
Mycobacterium tuberculosis modulators of the macrophage's cellular events.
Microbes and infection Nov, 2012 | Pubmed ID: 22841679
Chemical constituents, anti-inflammatory and antioxidant activities of bark extracts from Prunus tucumanensis Lillo.
Natural product research , 2013 | Pubmed ID: 22889184
Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development.
Trends in microbiology Feb, 2013 | Pubmed ID: 23084287
Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis.
Microbiology (Reading, England) Apr, 2013 | Pubmed ID: 23412844
Antimicrobial activity, cytotoxicity and inflammatory response of novel plastics embedded with silver nanoparticles.
Future microbiology Mar, 2013 | Pubmed ID: 23464375
Gaseous nitric oxide reduces influenza infectivity in vitro.
Nitric oxide : biology and chemistry May, 2013 | Pubmed ID: 23562771
Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.
PLoS pathogens , 2013 | Pubmed ID: 23874203
Microbial protein-tyrosine kinases.
The Journal of biological chemistry Apr, 2014 | Pubmed ID: 24554699
Mycobacterium tuberculosis promotes anti-apoptotic activity of the macrophage by PtpA protein-dependent dephosphorylation of host GSK3α.
The Journal of biological chemistry Oct, 2014 | Pubmed ID: 25187516
Phosphorylation control of protein tyrosine phosphatase A activity in Mycobacterium tuberculosis.
FEBS letters Jan, 2015 | Pubmed ID: 25535696
Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis.
Immunological reviews Mar, 2015 | Pubmed ID: 25703562
Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity.
The Journal of biological chemistry Sep, 2015 | Pubmed ID: 26229105
Phosphorylation of Mycobacterium tuberculosis protein tyrosine kinase A PtkA by Ser/Thr protein kinases.
Biochemical and biophysical research communications Nov, 2015 | Pubmed ID: 26417687
Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages.
Antimicrobial agents and chemotherapy Oct, 2015 | Pubmed ID: 26503663
Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis.
Cell reports Jan, 2016 | Pubmed ID: 26774486
Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms.
Microbiology spectrum Dec, 2015 | Pubmed ID: 27337278
Aminorifamycins and Sporalactams Produced in Culture by a Micromonospora sp. Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics.
Organic letters Feb, 2017 | Pubmed ID: 28164711
Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence.
Microbiology spectrum Mar, 2017 | Pubmed ID: 28281439
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