Jiashun Zheng

An approach to identify over-represented cis-elements in related sequences.

In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.

fREDUCE: detection of degenerate regulatory elements using correlation with expression.

De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis.

Epistatic relationships reveal the functional organization of yeast transcription factors.

Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes.

The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis.

Ago1 Interacts with RNA Polymerase II and Binds to the Promoters of Actively Transcribed Genes in Human Cancer Cells.

Heterogeneously expressed fezf2 patterns gradient Notch activity in balancing the quiescence, proliferation, and differentiation of adult neural stem cells.

Early telomerase inactivation accelerates aging independently of telomere length.

Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals "aging factors" and mechanism of lifespan asymmetry.

Conversion of human fibroblasts into functional cardiomyocytes by small molecules.

Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation.

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.

Brown Adipogenic Reprogramming Induced by a Small Molecule.

A global characterization of the translational and transcriptional programs induced by methionine restriction through ribosome profiling and RNA-seq.