Baruch Minke

Calmodulin regulation of light adaptation and store-operated dark current in Drosophila photoreceptors.

Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.

Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

A common mechanism underlies vertebrate calcium signaling and Drosophila phototransduction.

TRP channel proteins and signal transduction.

Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current.

Regulation of light-dependent Gqalpha translocation and morphological changes in fly photoreceptors.

The TRP calcium channel and retinal degeneration.

TRP gating is linked to the metabolic state and maintenance of the Drosophila photoreceptor cells.

Activation of the Drosophila TRP and TRPL channels requires both Ca2+ and protein dephosphorylation.

Novel dominant rhodopsin mutation triggers two mechanisms of retinal degeneration and photoreceptor desensitization.

Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors.

Excess of Gbetae over Gqalphae in vivo prevents dark, spontaneous activity of Drosophila photoreceptors.

Light-regulated translocation of signaling proteins in Drosophila photoreceptors.

Insights on TRP channels from in vivo studies in Drosophila.

Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade.

TRP channels and Ca2+ signaling.

Open channel block by Ca2+ underlies the voltage dependence of drosophila TRPL channel.

Translocation of Gq alpha mediates long-term adaptation in Drosophila photoreceptors.

Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels.

Membrane lipid modulations remove divalent open channel block from TRP-like and NMDA channels.

Linoleic acid inhibits TRP channels with intrinsic voltage sensitivity: Implications on the mechanism of linoleic acid action.

Drosophila photoreceptors and signaling mechanisms.

Constitutive activity of the human TRPML2 channel induces cell degeneration.

Cellular functions of transient receptor potential channels.

Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy.

Constitutive activity of TRP channels methods for measuring the activity and its outcome.

The history of the Drosophila TRP channel: the birth of a new channel superfamily.

Cell biology. Rhodopsin as thermosensor?

Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry.

Signal-dependent hydrolysis of phosphatidylinositol 4,5-bisphosphate without activation of phospholipase C: implications on gating of Drosophila TRPL (transient receptor potential-like) channel.

Phospholipase C-mediated suppression of dark noise enables single-photon detection in Drosophila photoreceptors.

The history of the prolonged depolarizing afterpotential (PDA) and its role in genetic dissection of Drosophila phototransduction.

The activity of the TRP-like channel depends on its expression system.

Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice.

Compartmentalization and Ca2+ buffering are essential for prevention of light-induced retinal degeneration.

Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo.

A new genetic model for calcium induced autophagy and ER-stress in Drosophila photoreceptor cells.

Functional cooperation between the IP3 receptor and phospholipase C secures the high sensitivity to light of Drosophila photoreceptors in vivo.

Ectopic Expression of Mouse Melanopsin in Drosophila Photoreceptors Reveals Fast Response Kinetics and Persistent Dark Excitation.

The Phosphorylation State of the Drosophila TRP Channel Modulates the Frequency Response to Oscillating Light In Vivo.

The latency of the light response is modulated by the phosphorylation state of Drosophila TRP at a specific site.

Depletion of Membrane Cholesterol Suppresses Drosophila Transient Receptor Potential-Like (TRPL) Channel Activity.

The Drosophila light-activated TRP and TRPL channels - Targets of the phosphoinositide signaling cascade.

Comparative docking analysis of cholesterol analogs to ion channels to discriminate between stereospecific binding vs. stereospecific response.

Modulation of Transient Receptor Potential C Channel Activity by Cholesterol.

Knockdown of Dehydrodolichyl Diphosphate Synthase in the Retina Leads to a Unique Pattern of Retinal Degeneration.

The Role of Membrane Lipids in Light-Activation of TRP Channels.

The light-activated TRP channel: the founding member of the TRP channel superfamily.

Nociception and pain in humans lacking a functional TRPV1 channel.

Electroretinogram (ERG) Recordings from .