IBiTech-MEDISIP,
Department of Electronics and Information Systems,
Infinity lab,
Medical Imaging and Signal Processing Group,
IBiTech-MEDISIP, Department of Electronics and Information Systems,
Infinity lab, Medical Imaging and Signal Processing Group
Christian Vanhove graduated as a Biomedical Engineer from Brussels University in 1990. From 1991-2011, he worked as medical physicist expert in nuclear medicine with research focussing on all aspects of medical image processing and analysis. He obtained a PhD in Medical Sciences in 2004 at Brussels University. In 2005, he was one of the initiators of the laboratory animal imaging facility of Brussels University, where he worked as a postdoctoral researcher. During this period his research was focused on imaging quantification in laboratory animal imaging. Since 2011, he joined the Institute of Biomedical Engineering and Technology of the Faculty of Engineering and Architecture of Ghent University, where he is director of the laboratory animal imaging facility. Christian Vanhove is associate professor and lecturer in biomedical engineering.
Magnetic resonace-based attenuation correction for micro-single-photon emission computed tomography.
Molecular imaging Apr, 2012 | Pubmed ID: 22469243
In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier.
Biomaterials Mar, 2013 | Pubmed ID: 23261216
In vivo visualization and quantification of (Disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Apr, 2013 | Pubmed ID: 23440558
Temperature dependence of APD-based PET scanners.
Medical physics Sep, 2013 | Pubmed ID: 24007182
Role of metallothioneins as danger signals in the pathogenesis of colitis.
The Journal of pathology May, 2014 | Pubmed ID: 24452846
MRI-guided 3D conformal arc micro-irradiation of a F98 glioblastoma rat model using the Small Animal Radiation Research Platform (SARRP).
Journal of neuro-oncology Nov, 2014 | Pubmed ID: 25069566
Fate of xylem-transported 11C- and 13C-labeled CO2 in leaves of poplar.
Physiologia plantarum Apr, 2015 | Pubmed ID: 25142926
(18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study.
Nuclear medicine and biology Jan, 2015 | Pubmed ID: 25218024
Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling.
Cancer research Dec, 2014 | Pubmed ID: 25252914
Hippocampal deep brain stimulation reduces glucose utilization in the healthy rat brain.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Jun, 2015 | Pubmed ID: 25361593
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.
Biomaterials Jun, 2015 | Pubmed ID: 25907048
Functional MRI during Hippocampal Deep Brain Stimulation in the Healthy Rat Brain.
PloS one , 2015 | Pubmed ID: 26193653
Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.
Medical physics Aug, 2015 | Pubmed ID: 26233207
Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model.
Oncotarget Oct, 2015 | Pubmed ID: 26375674
Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling.
Oncotarget Sep, 2015 | Pubmed ID: 26396176
Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Jan, 2016 | Pubmed ID: 26449837
Collimator design for a multipinhole brain SPECT insert for MRI.
Medical physics Nov, 2015 | Pubmed ID: 26520758
Accurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performance.
EJNMMI physics Dec, 2015 | Pubmed ID: 26560138
MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP).
PloS one , 2015 | Pubmed ID: 26633302
Quantitative and Functional Requirements for Bioluminescent Cancer Models.
In vivo (Athens, Greece) Jan-Feb, 2016 | Pubmed ID: 26709122
Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.
Contrast media & molecular imaging Sep, 2016 | Pubmed ID: 27147480
Repetitive transcranial magnetic stimulation for the treatment of refractory epilepsy.
Expert review of neurotherapeutics Sep, 2016 | Pubmed ID: 27254399
Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function.
Nuclear medicine and biology Oct, 2016 | Pubmed ID: 27513813
Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination between High-Grade Glioma and Radiation Necrosis in Rats.
PloS one , 2016 | Pubmed ID: 27559736
Functional circuit mapping of striatal output nuclei using simultaneous deep brain stimulation and fMRI.
NeuroImage Feb, 2017 | Pubmed ID: 27825979
Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
The Journal of pathology Mar, 2017 | Pubmed ID: 27981571
18F-FCho PET and MRI for the prediction of response in glioblastoma patients according to the RANO criteria.
Nuclear medicine communications Mar, 2017 | Pubmed ID: 27984537
The VEGFR Inhibitor Cediranib Improves the Efficacy of Fractionated Radiotherapy in a Colorectal Cancer Xenograft Model.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes , 2017 | Pubmed ID: 28002822
Mathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule.
Drug delivery Nov, 2017 | Pubmed ID: 28181817
Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice.
PloS one , 2017 | Pubmed ID: 28273180
In Vivo DCE-MRI for the Discrimination Between Glioblastoma and Radiation Necrosis in Rats.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Dec, 2017 | Pubmed ID: 28303489
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection.
Oncology reports Jul, 2017 | Pubmed ID: 28504813
Use of a Ray-Based Reconstruction Algorithm to Accurately Quantify Preclinical MicroSPECT Images.
Molecular imaging Jun, 2014 | Pubmed ID: 28650292
Vulnerable Plaque Detection and Quantification with Gold Particle-Enhanced Computed Tomography in Atherosclerotic Mouse Models.
Molecular imaging May, 2015 | Pubmed ID: 28654406
Toward smart design of retinal drug carriers: a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface.
Drug delivery Nov, 2017 | Pubmed ID: 28925755
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2017 | Pubmed ID: 28987878
TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Scientific reports Oct, 2017 | Pubmed ID: 29057962
Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF-1R activation.
Cancer research Dec, 2017 | Pubmed ID: 29217764
ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Mar, 2018 | Pubmed ID: 29269093
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.
Biomaterials 03, 2018 | Pubmed ID: 29306747
Adipose-Derived Mesenchymal Stromal Cells Improve the Healing of Colonic Anastomoses Following High Dose of Irradiation Through Anti-Inflammatory and Angiogenic Processes.
Cell transplantation 12, 2017 | Pubmed ID: 29390877
Hypoxia imaging with F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts.
Radiation oncology (London, England) Mar, 2018 | Pubmed ID: 29514673
Evaluating Hepatobiliary Transport with F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and and Performance.
Contrast media & molecular imaging , 2018 | Pubmed ID: 29853807
Regional alterations of cerebral [F]FDG metabolism in the chronic unpredictable mild stress- and the repeated corticosterone depression model in rats.
Journal of neural transmission (Vienna, Austria : 1996) Sep, 2018 | Pubmed ID: 29955973
Performance evaluation of the LightPath imaging system for intra-operative Cerenkov luminescence imaging.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Aug, 2018 | Pubmed ID: 30139600
Angiopoietin-2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease.
Hepatology (Baltimore, Md.) Mar, 2019 | Pubmed ID: 30259536
Species-dependent extracranial manifestations of a brain seeking breast cancer cell line.
PloS one , 2018 | Pubmed ID: 30532191
Magnetic resonance imaging-guided radiation therapy using animal models of glioblastoma.
The British journal of radiology Mar, 2019 | Pubmed ID: 30563357
Validation of hepatobiliary transport PET imaging in liver function assessment: Evaluation of 3β-[F]FCA in mouse models of liver disease.
Nuclear medicine and biology Jan - Feb, 2019 | Pubmed ID: 30595544
Plant-PET to investigate phloem vulnerability to drought in Populus tremula under changing climate regimes.
Tree physiology 02, 2019 | Pubmed ID: 30597097
Dynamic changes in hippocampal diffusion and kurtosis metrics following experimental mTBI correlate with glial reactivity.
NeuroImage. Clinical , 2019 | Pubmed ID: 30658945
The Path Toward PET-Guided Radiation Therapy for Glioblastoma in Laboratory Animals: A Mini Review.
Frontiers in medicine , 2019 | Pubmed ID: 30761302
New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma.
Scientific reports Feb, 2019 | Pubmed ID: 30814660
Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review.
World journal of gastrointestinal oncology Mar, 2019 | Pubmed ID: 30918597
A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy.
Drug delivery Dec, 2019 | Pubmed ID: 30929523
In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31016649
Technical feasibility of [F]FET and [F]FAZA PET guided radiotherapy in a F98 glioblastoma rat model.
Radiation oncology (London, England) May, 2019 | Pubmed ID: 31146757
PET quantification of [18F]MPPF in the canine brain using blood input and reference tissue modelling.
PloS one , 2019 | Pubmed ID: 31185062
Non-viral delivery of chemically modified mRNA to the retina: Subretinal versus intravitreal administration.
Journal of controlled release : official journal of the Controlled Release Society Jun, 2019 | Pubmed ID: 31265881
Alterations in the functional brain network in a rat model of epileptogenesis: A longitudinal resting state fMRI study.
NeuroImage 11, 2019 | Pubmed ID: 31473355
Standardization of Preclinical PET/CT Imaging to Improve Quantitative Accuracy, Precision, and Reproducibility: A Multicenter Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 03, 2020 | Pubmed ID: 31562220
Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study.
PloS one , 2019 | Pubmed ID: 31634381
Kinetic analysis of [F] altanserin bolus injection in the canine brain using PET imaging.
BMC veterinary research Nov, 2019 | Pubmed ID: 31752848
2-[F]FELP, a novel LAT1-specific PET tracer, for the discrimination between glioblastoma, radiation necrosis and inflammation.
Nuclear medicine and biology Mar - Apr, 2020 | Pubmed ID: 31841816
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis.
Oncogene 03, 2020 | Pubmed ID: 32001819
Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration.
Neurobiology of disease 06, 2020 | Pubmed ID: 32087287
Biomechanical comparison of Thiel embalmed and fresh frozen nerve tissue.
Anatomical science international Jun, 2020 | Pubmed ID: 32144646
Cx43 channels and signaling via IP/Ca, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells.
Cell death & disease 03, 2020 | Pubmed ID: 32188841
Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects.
Human molecular genetics 06, 2020 | Pubmed ID: 32307537
Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging.
Molecules (Basel, Switzerland) Apr, 2020 | Pubmed ID: 32316285
Studying in vivo dynamics of xylem-transported 11CO2 using positron emission tomography.
Tree physiology 07, 2020 | Pubmed ID: 32333788
Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [F]fluorophenylglutamine and [F]fluorobiphenylglutamine.
Nuclear medicine and biology Jul - Aug, 2020 | Pubmed ID: 32447069
Radiosynthesis, in vitro and preliminary biological evaluation of [ F]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino)butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer.
Journal of labelled compounds & radiopharmaceuticals 08, 2020 | Pubmed ID: 32472945
Synergy between Intraperitoneal Aerosolization (PIPAC) and Cancer Nanomedicine: Cisplatin-Loaded Polyarginine-Hyaluronic Acid Nanocarriers Efficiently Eradicate Peritoneal Metastasis of Advanced Human Ovarian Cancer.
ACS applied materials & interfaces Jul, 2020 | Pubmed ID: 32506916
Can medical imaging identify the histopathological growth patterns of liver metastases?
Seminars in cancer biology 06, 2021 | Pubmed ID: 32735852
Development of a Rat Model for Glioma-Related Epilepsy.
International journal of molecular sciences Sep, 2020 | Pubmed ID: 32977526
Anti-human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation.
Biomolecules 09, 2020 | Pubmed ID: 33003481
The shrimp nephrocomplex serves as a major portal of pathogen entry and is involved in the molting process.
Proceedings of the National Academy of Sciences of the United States of America 11, 2020 | Pubmed ID: 33097672
In vivo selection of the MDA-MB-231br/eGFP cancer cell line to obtain a clinically relevant rat model for triple negative breast cancer brain metastasis.
PloS one , 2020 | Pubmed ID: 33264355
Intra-individual dynamic comparison of F-PSMA-11 and Ga-PSMA-11 in LNCaP xenograft bearing mice.
Scientific reports 12, 2020 | Pubmed ID: 33273603
Long-term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy.
Epilepsia 03, 2021 | Pubmed ID: 33570167
Assessment of the effect of therapy in a rat model of glioblastoma using [18F]FDG and [18F]FCho PET compared to contrast-enhanced MRI.
PloS one , 2021 | Pubmed ID: 33667282
Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells.
Biomaterials science Jun, 2021 | Pubmed ID: 33899850
Hydrogel-Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane-Impermeable Cargo.
Advanced materials (Deerfield Beach, Fla.) Jul, 2021 | Pubmed ID: 34106486
Guide to Plant-PET Imaging Using CO.
Frontiers in plant science , 2021 | Pubmed ID: 34149742
White Matter Integrity in a Rat Model of Epileptogenesis: Structural Connectomics and Fixel-Based Analysis.
Brain connectivity Aug, 2021 | Pubmed ID: 34155915
Comparison of In Vivo and Ex Vivo Magnetic Resonance Imaging in a Rat Model for Glioblastoma-Associated Epilepsy.
Diagnostics (Basel, Switzerland) Jul, 2021 | Pubmed ID: 34441246
High-Resolution F-FDG PET/CT for Assessing Three-Dimensional Intraoperative Margins Status in Malignancies of the Head and Neck, a Proof-of-Concept.
Journal of clinical medicine Aug, 2021 | Pubmed ID: 34442033
Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus.
eNeuro Nov-Dec, 2021 | Pubmed ID: 34620623
Non-invasive cell-tracking methods for adoptive T cell therapies.
Drug discovery today Mar, 2022 | Pubmed ID: 34718210
Voxel-Based Analysis of [18F]-FDG Brain PET in Rats Using Data-Driven Normalization.
Frontiers in medicine , 2021 | Pubmed ID: 34746179
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping.
Proceedings of the National Academy of Sciences of the United States of America 11, 2021 | Pubmed ID: 34789568
Impact of the molar activity and PSMA expression level on [F]AlF-PSMA-11 uptake in prostate cancer.
Scientific reports 11, 2021 | Pubmed ID: 34799653
Recent advancements in F-labeled PSMA targeting PET radiopharmaceuticals.
Nuclear medicine and biology Mar-Apr, 2022 | Pubmed ID: 34998217
Performance evaluation of a micro-CT system for laboratory animal imaging with iterative reconstruction capabilities.
Medical physics Feb, 2022 | Pubmed ID: 35170057
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