Ka-Fai To

Consistent chromosome 10 rearrangements in four newly established human hepatocellular carcinoma cell lines.

Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma.

Genome wide detection of oncogene amplifications in nasopharyngeal carcinoma by array based comparative genomic hybridization.

Primary IgA nephropathy with low histologic grade and disease progression: is there a "point of no return"?

Case report: human herpesvirus 7 associated fatal encephalitis in a peripheral blood stem cell transplant recipient.

Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma.

Renal outcome in type 2 diabetic patients with or without coexisting nondiabetic nephropathies.

Impaired expression and promotor hypermethylation of O6-methylguanine-DNA methyltransferase in retinoblastoma tissues.

Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma.

Gonadal mosaicism of Frasier syndrome in 3 Chinese siblings with donor splice site mutation of Wilms' tumour gene.

Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

Quantitative Epstein-Barr virus DNA analysis and detection of gene promoter hypermethylation in nasopharyngeal (NP) brushing samples from patients with NP carcinoma.

In vivo diagnosis of persistent and recurrent nasopharyngeal carcinoma by contact endoscopy.

Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese.

Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma.

Nasopharyngeal carcinoma in situ (NPCIS)--pathologic and clinical perspectives.

Identification of four distinct regions of allelic imbalances on chromosome 1 by the combined comparative genomic hybridization and microsatellite analysis on hepatocellular carcinoma.

Promoter hypermethylation of tumor-related genes in gastric intestinal metaplasia of patients with and without gastric cancer.

Positional mapping for amplified DNA sequences on 1q21-q22 in hepatocellular carcinoma indicates candidate genes over-expression.

Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients.

Promoter hypermethylation of cyclooxygenase-2 in gastric carcinoma.

Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer.

A novel mutation (G233D) in the glycogen phosphorylase gene in a patient with hepatic glycogen storage disease and residual enzyme activity.

Rapid clearance of plasma Epstein-Barr virus DNA after surgical treatment of nasopharyngeal carcinoma.

Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection.

Human metapneumovirus detection in patients with severe acute respiratory syndrome.

Magnetic resonance colonography in the detection of colonic neoplasm in high-risk and average-risk individuals.

RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma.

Human metapneumovirus-associated atypical pneumonia and SARS.

Focus on nasopharyngeal carcinoma.

Isolate diffuse thickening of glomerular capillary basement membrane: a renal lesion in prediabetes?

Persistent infection of SARS coronavirus in colonic cells in vitro.

Microsatellite instability and MLH1 promoter methylation in human retinoblastoma.

Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma.

Quantitative detection of methylated SOCS-1 , a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection.

Detection of epigenetic changes in fecal DNA as a molecular screening test for colorectal cancer: a feasibility study.

Regional over-representations on chromosomes 1q, 3q and 7q in the progression of hepatitis B virus-related hepatocellular carcinoma.

Different cell kinetic changes in rat stomach cancer after treatment with celecoxib or indomethacin: implications on chemoprevention.

Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma.

Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma.

Alveolar capillary dysplasia with congenital misalignment of pulmonary vessels.

Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer.

Detection and quantitation of human papillomavirus DNA in primary tumour and lymph nodes of patients with early stage cervical carcinoma.

Coronaviral hypothetical and structural proteins were found in the intestinal surface enterocytes and pneumocytes of severe acute respiratory syndrome (SARS).

Long-term outcome of Helicobacter pylori-negative idiopathic bleeding ulcers: a prospective cohort study.

Twelve-year follow up of a randomized prospective trial comparing bacillus Calmette-Guerin and epirubicin as adjuvant therapy in superficial bladder cancer.

Prenatal embolisation of a large chorioangioma using enbucrilate.

The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells.

Biases in human papillomavirus genotype prevalence assessment associated with commonly used consensus primers.

Pediatric malignancies. Case 1. Hypermethylation in orbital alveolar rhabdomyosarcoma.

Clonal relationship of tumor nodules in hepatocellular carcinoma: a hierarchical clustering analysis of comparative genomic hybridization data.

In vivo real-time diagnosis of nasopharyngeal carcinoma in situ by contact rhinoscopy.

Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma.

Early enhanced expression of interferon-inducible protein-10 (CXCL-10) and other chemokines predicts adverse outcome in severe acute respiratory syndrome.

Investigation into the origin and tumoral mass correlation of plasma Epstein-Barr virus DNA in nasopharyngeal carcinoma.

How the SARS coronavirus causes disease: host or organism?

Hong Kong case-control study of sudden unexpected infant death.

Genome-wide detection of allelic imbalance in renal cell carcinoma using high-density single-nucleotide polymorphism microarrays.

Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells.

H. pylori genotypes and cytokine gene polymorphisms influence the development of gastric intestinal metaplasia in a Chinese population.

Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in noncancerous stomach.

Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.

Prevalence and implications of isolated microscopic hematuria in asymptomatic Chinese pregnant women.

The 3a Protein of SARS-coronavirus Induces Apoptosis in Vero E6 Cells.

Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps.

HLA-DQB1 polymorphisms and risk for cervical cancer: a case-control study in a southern Chinese population.

Identification of PFTAIRE protein kinase 1, a novel cell division cycle-2 related gene, in the motile phenotype of hepatocellular carcinoma cells.

Quantitative temporal-spatial distribution of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in post-mortem tissues.

Effect of Scutellariae Radix extract on experimental dextran-sulfate sodium-induced colitis in rats.

MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.

Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice.

Helicobacter pylori-positive versus Helicobacter pylori-negative idiopathic peptic ulcers in children with their long-term outcomes.

High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers.

Repeat-screening colonoscopy 5 years after normal baseline-screening colonoscopy in average-risk Chinese: a prospective study.

Distribution of human papillomavirus types in cervical cancers in Hong Kong: current situation and changes over the last decades.

Post-transplant EBV-related lymphoproliferative disorder complicating umbilical cord blood transplantation in patients of adrenoleukodystrophy.

Glucose-regulated protein 78 is an intracellular antiviral factor against hepatitis B virus.

Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinoma.

Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response.

Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22.

Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use.

The host defense peptide LL-37 activates the tumor-suppressing bone morphogenetic protein signaling via inhibition of proteasome in gastric cancer cells.

Second-trimester detection of Mowat-Wilson syndrome using comparative genomic hybridization microarray testing.

MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling.

Radiological appearance of inflammatory myofibroblastic tumour.

Late retroperitoneal recurrence of hepatocellular carcinoma 12 years after initial diagnosis.

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b). IMFT of the bladder.

14-3-3sigma expression as a prognostic marker in undifferentiated nasopharyngeal carcinoma.

Massive subchorionic thrombohematoma: a series of 10 cases.

Sequencing analysis of the 3' region of the cagA gene in Helicobacter pylori isolated from Hong Kong Chinese patients.

Novel mutations in PHKA2 gene in glycogen storage disease type IX patients from Hong Kong, China.

Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis.

Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine.

Zinc finger E-box binding factor 1 plays a central role in regulating Epstein-Barr virus (EBV) latent-lytic switch and acts as a therapeutic target in EBV-associated gastric cancer.

Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches.

MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma.

Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer.

Immunoregulatory protein profiles of necrotizing enterocolitis versus spontaneous intestinal perforation in preterm infants.

Endoscopic submucosal dissection (ESD) compared with gastrectomy for treatment of early gastric neoplasia: a retrospective cohort study.

A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma.

Genome-wide identification of Epstein-Barr virus-driven promoter methylation profiles of human genes in gastric cancer cells.

Dapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-κB signaling pathway.

CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.

MicroRNA-182 plays an onco-miRNA role in cervical cancer.

Enhancer of zeste homolog 2 silences microRNA-218 in human pancreatic ductal adenocarcinoma cells by inducing formation of heterochromatin.

Detection of ALK Rearrangement by Immunohistochemistry in Lung Adenocarcinoma and the Identification of a Novel EML4-ALK Variant.

Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells.

Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.

Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.

Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.

Emerging roles of small Epstein-Barr virus derived non-coding RNAs in epithelial malignancy.

TTF-1 expression in breast carcinoma: an unusual but real phenomenon.

CRTC3-MAML2 fusion transcript in a bronchial mucoepidermoid carcinoma.

Prolonged non-survival in PICU: does a do-not-attempt-resuscitation order matter.

Hydrops fetalis, hepatic centrolobular necrosis, and hypoxic-ischaemic encephalopathy in a fetus with premature closure of foramen ovale.

Genome-wide expression profiles of necrotizing enterocolitis versus spontaneous intestinal perforation in human intestinal tissues: dysregulation of functional pathways.

An uncommon insertion mutation in exon 19 of EGFR showed stable disease after TKI treatment.

Evaluation of histological staging systems for primary biliary cirrhosis: correlation with clinical and biochemical factors and significance of pathological parameters in prognostication.

Expression of stemness markers (CD133 and EpCAM) in prognostication of hepatocellular carcinoma.

Viral-human chimeric transcript predisposes risk to liver cancer development and progression.

Overexpression of ZFX confers self-renewal and chemoresistance properties in hepatocellular carcinoma.

Yin Yang 1 contributes to gastric carcinogenesis and its nuclear expression correlates with shorter survival in patients with early stage gastric adenocarcinoma.

Epstein-Barr virus-associated lymphoepithelioma-like cholangiocarcinoma: a rare variant of intrahepatic cholangiocarcinoma with favourable outcome.

Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer.

A 20-year prospective study of Wilms tumor and other kidney tumors: a report from Hong Kong pediatric hematology and oncology study group.

miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis.

Reply to the letter to the editor: a rare case of breast cancer showing distinct TTF-1 nuclear expression: small-cell carcinoma or not?

Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinoma.

Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer.

let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis.

Anti-atherogenic effect of hydrogen sulfide by over-expression of cystathionine gamma-lyase (CSE) gene.

Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus.

A CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients.

Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer.

Lymphoepithelioma-like hepatocellular carcinoma: an uncommon variant of hepatocellular carcinoma with favorable outcome.

Albumin-to-alkaline phosphatase ratio: a novel prognostic index for hepatocellular carcinoma.

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma.

New simple prognostic score for primary biliary cirrhosis: Albumin-bilirubin score.

Prognostic Nutritional Index (PNI) Predicts Tumor Recurrence of Very Early/Early Stage Hepatocellular Carcinoma After Surgical Resection.

Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis.

Clinical utility of plasma Epstein-Barr virus DNA and ERCC1 single nucleotide polymorphism in nasopharyngeal carcinoma.

Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer.

Phase I/II study of temsirolimus for patients with unresectable Hepatocellular Carcinoma (HCC)- a correlative study to explore potential biomarkers for response.

Differential MicroRNA Expression in Human Macrophages with Mycobacterium tuberculosis Infection of Beijing/W and Non-Beijing/W Strain Types.

Paradoxical hypertension and salt wasting in Type II Bartter syndrome.

Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor.

Alveolar rhabdomyosarcoma of the anterior mediastinum with vessel invasion in a 4-month-old boy: a case report.

Comparative MiRNA Expressional Profiles and Molecular Networks in Human Small Bowel Tissues of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation.

The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers.

TGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosis.

Integration of albumin-bilirubin (ALBI) score into Barcelona Clinic Liver Cancer (BCLC) system for hepatocellular carcinoma.

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

miR-508-3p concordantly silences NFKB1 and RELA to inactivate canonical NF-κB signaling in gastric carcinogenesis.

The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis.

Emerging role of Hippo pathway in gastric and other gastrointestinal cancers.

MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non-Small Cell Lung Carcinoma with Poor Prognosis.

Dysregulated expression of arginine metabolic enzymes in human intestinal tissues of necrotizing enterocolitis and response of CaCO2 cells to bacterial components.

Applicability of albumin-bilirubin-based Japan integrated staging score in hepatitis B-associated hepatocellular carcinoma.

Tumor risk of children with 45,X/46,XY gonadal dysgenesis in relation to their clinical presentations: Further insights into the gonadal management.

A new prognostic histopathologic classification of nasopharyngeal carcinoma.

Unraveling methylation changes of host macrophages in Mycobacterium tuberculosis infection.

Incorporating albumin-bilirubin grade into the cancer of the liver Italian program system for hepatocellular carcinoma.

Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse.

MET DNA Alterations in NSCLC-Reply.

SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.

Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.

Importance of Estrogenic Signaling and Its Mediated Receptors in Prostate Cancer.

EZH2 coupled with HOTAIR to silence MicroRNA-34a by the induction of heterochromatin formation in human pancreatic ductal adenocarcinoma.

Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.

Is there significance in identification of non-predominant micropapillary or solid components in early-stage lung adenocarcinoma?

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis.

Activation of GPR30 stimulates GTP-binding of Gαi1 protein to sustain activation of Erk1/2 in inhibition of prostate cancer cell growth and modulates metastatic properties.

NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations.

Elevated PRC1 in gastric carcinoma exerts oncogenic function and is targeted by piperlongumine in a p53-dependent manner.

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury.

The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis.

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development.

IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis.

Topical Application of Mesenchymal Stromal Cells Ameliorated Liver Parenchyma Damage After Ischemia-Reperfusion Injury in an Animal Model.

Albumin-bilirubin grade predicts the outcomes of liver resection versus radiofrequency ablation for very early/early stage of hepatocellular carcinoma.

Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics.

The large tumor suppressor family: friend or foe?

Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis.

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma.

Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.

The oncogenic role of Epstein-Barr virus-encoded microRNAs in Epstein-Barr virus-associated gastric carcinoma.

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring.

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis.

Molecular and functional characterization of tumor-induced factor (TIF): Hamster homolog of CXCL3 (GROγ) displays tumor suppressive activity.