Hui-Yao Lan

Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.

The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential.

Transforming growth factor-β and Smads.

Diabetes complications: the microRNA perspective.

Diverse roles of TGF-β/Smads in renal fibrosis and inflammation.

Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.

Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro.

Transforming growth factor-β/Smad signalling in diabetic nephropathy.

Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro.

TGF-β/Smad signaling in kidney disease.

Smad7 inhibits angiotensin II-induced hypertensive cardiac remodelling.

Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension.

Dragon (repulsive guidance molecule RGMb) inhibits E-cadherin expression and induces apoptosis in renal tubular epithelial cells.

Identification of novel long noncoding RNAs associated with TGF-β/Smad3-mediated renal inflammation and fibrosis by RNA sequencing.

miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling.

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.

Application of microRNAs in diabetes mellitus.

Latent transforming growth factor-β1 protects against bleomycin-induced lung injury in mice.

Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro.

Inflammatory processes in renal fibrosis.

Partial loss of Smad7 function impairs bone remodeling, osteogenesis and enhances osteoclastogenesis in mice.

MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis.

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway.

Metabolomic and lipidomic study of the protective effect of Chaihuang-Yishen formula on rats with diabetic nephropathy.

Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation.

TGF-β/Smad signaling in renal fibrosis.

Transient receptor potential channel M2 contributes to neointimal hyperplasia in vascular walls.

Renoprotective effect of berberine on type 2 diabetic nephropathy in rats.

Smad7 protects against chronic aristolochic acid nephropathy in mice.

Deletion of Smad3 improves cardiac allograft rejection in mice.

Macrophages promote renal fibrosis through direct and indirect mechanisms.

Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin.

N-Acetyl-seryl-aspartyl-lysyl-proline Alleviates Renal Fibrosis Induced by Unilateral Ureteric Obstruction in BALB/C Mice.

TGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosis.

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in Rats.

Peritoneal inflammation and fibrosis in C-reactive protein transgenic mice undergoing peritoneal dialysis solution treatment.

Smads as therapeutic targets for chronic kidney disease.

TGF-β: the master regulator of fibrosis.

Validity of leptin receptor-deficiency (db/db) type 2 diabetes mellitus mice as a model of secondary osteoporosis.

C-reactive protein promotes acute kidney injury via Smad3-dependent inhibition of CDK2/cyclin E.

Macrophage Phenotype in Kidney Injury and Repair.

Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models.

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis.

The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation.

N-acetyl-seryl-aspartyl-lysyl-proline Mediates the Anti-fibrotic Properties of Captopril in Unilateral Ureteric Obstructed BALB/C Mice.

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury.

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development.

C-reactive protein and ageing.

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis.

Smad7 protects against acute kidney injury by rescuing tubular epithelial cells from the G1 cell cycle arrest.

The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery.

Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis.

Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation.

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring.

TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis.

Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b.

Lethal (3) malignant brain tumor like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage-p53-apoptosis pathway in renal tubular cells.