Knock Out Mouse Core
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Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice.
Prostaglandins & other lipid mediators Nov, 2011 | Pubmed ID: 21742052
Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathy.
American journal of physiology. Endocrinology and metabolism Sep, 2012 | Pubmed ID: 22739108
EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides.
Journal of lipid research Oct, 2012 | Pubmed ID: 22798687
Regulation of T helper cell subsets by cyclooxygenases and their metabolites.
Prostaglandins & other lipid mediators Nov, 2012 | Pubmed ID: 23201570
Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily.
Drug metabolism and disposition: the biological fate of chemicals Apr, 2013 | Pubmed ID: 23315644
COX-2 Inhibits Th9 Differentiation During Allergic Lung Inflammation Via Downregulation of IL-17RB.
American journal of respiratory and critical care medicine Feb, 2013 | Pubmed ID: 23449692
The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.
PloS one , 2014 | Pubmed ID: 25310404
CYP2J2 attenuates metabolic dysfunction in diabetic mice by reducing hepatic inflammation via the PPARγ.
American journal of physiology. Endocrinology and metabolism Feb, 2015 | Pubmed ID: 25389363
Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction.
Journal of cellular physiology Sep, 2015 | Pubmed ID: 25626689
Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation.
Drug metabolism and disposition: the biological fate of chemicals Aug, 2015 | Pubmed ID: 25994032
Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2016 | Pubmed ID: 26396235
Plasma 15-Hydroxyeicosatetraenoic Acid Predicts Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease.
The journal of allergy and clinical immunology. In practice Jul - Aug, 2017 | Pubmed ID: 28159558
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G) to Affect Vascular Function and Trigger Hypertension.
Circulation research May, 2017 | Pubmed ID: 28325781
Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice.
PloS one , 2017 | Pubmed ID: 28384353
Characterization of the Tissue Distribution of the Mouse Subfamily by Quantitative PCR Analysis.
Drug metabolism and disposition: the biological fate of chemicals 07, 2017 | Pubmed ID: 28450579
Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.
The FEBS journal 07, 2017 | Pubmed ID: 28485854
Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.
Biochimica et biophysica acta. General subjects Nov, 2017 | Pubmed ID: 28757338
Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.
The Journal of biological chemistry Mar, 2018 | Pubmed ID: 29298899
En masse lentiviral gene delivery to mouse fertilized eggs via laser perforation of zona pellucida.
Transgenic research 02, 2018 | Pubmed ID: 29442214
Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.
Human molecular genetics Sep, 2018 | Pubmed ID: 30212841
Negin P. Martin*,1,
Page Myers*,2,
Eugenia Goulding1,
Shih-Heng Chen1,
Mitzie Walker1,
Thomas M. Porter1,
Lucas Van Gorder1,
Amanda Mathew1,
Artiom Gruzdev3,
Erica Scappini4,
Charles Romeo1
1Neurobiology Laboratory, National Institute of Environmental Health Sciences,
2Comparative Medicine Branch, National Institute of Environmental Health Sciences,
3Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences,
4Signal Transduction Laboratory, National Institute of Environmental Health Sciences
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