Department of Microbiology and Immunology
Michael R. Gold has not added Biography.
If you are Michael R. Gold and would like to personalize this page please email our Author Liaison for assistance.
Listeria monocytogenes invasion of epithelial cells requires the MEK-1/ERK-2 mitogen-activated protein kinase pathway.
Infection and immunity Mar, 1998 | Pubmed ID: 9488402
Dendritic cell survival and maturation are regulated by different signaling pathways.
The Journal of experimental medicine Dec, 1998 | Pubmed ID: 9841930
Interaction of cationic peptides with lipoteichoic acid and gram-positive bacteria.
Infection and immunity Dec, 1999 | Pubmed ID: 10569762
CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2002 | Pubmed ID: 11777968
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.
Molecular and cellular biology Apr, 2002 | Pubmed ID: 11909947
Activation and phosphatidylinositol 3-kinase-dependent phosphorylation of protein kinase C-epsilon by the B cell antigen receptor.
Immunology letters Jul, 2002 | Pubmed ID: 12036603
The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2002 | Pubmed ID: 12097378
To make antibodies or not: signaling by the B-cell antigen receptor.
Trends in pharmacological sciences Jul, 2002 | Pubmed ID: 12119152
The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2002 | Pubmed ID: 12133960
The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2002 | Pubmed ID: 12244186
Akt is TCL-ish: implications for B-cell lymphoma.
Trends in immunology Mar, 2003 | Pubmed ID: 12615201
Activation of the Rap GTPases in B lymphocytes modulates B cell antigen receptor-induced activation of Akt but has no effect on MAPK activation.
The Journal of biological chemistry Oct, 2003 | Pubmed ID: 12904304
The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes.
The Journal of biological chemistry Mar, 2004 | Pubmed ID: 14701796
The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes.
European journal of immunology Aug, 2006 | Pubmed ID: 16821235
The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.
Immunity Jan, 2008 | Pubmed ID: 18191594
B cell development: important work for ERK.
Immunity Apr, 2008 | Pubmed ID: 18400191
Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4.
Journal of cell communication and signaling Jun, 2007 | Pubmed ID: 18481208
Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2009 | Pubmed ID: 19553538
B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.
The Journal of biological chemistry Aug, 2009 | Pubmed ID: 19561089
Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis.
The Journal of biological chemistry Oct, 2009 | Pubmed ID: 19700408
Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2009 | Pubmed ID: 19843950
Rap GTPase-mediated adhesion and migration: A target for limiting the dissemination of B-cell lymphomas?
Cell adhesion & migration Jul-Sep, 2010 | Pubmed ID: 20212359
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs.
Cancer research Jun, 2010 | Pubmed ID: 20484042
TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells.
European journal of immunology Feb, 2011 | Pubmed ID: 21268004
Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration.
PloS one Apr, 2011 | Pubmed ID: 21494591
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2011 | Pubmed ID: 22068232
Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells.
Cellular immunology Jan-Feb, 2012 | Pubmed ID: 22507871
Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice.
Autoimmunity Feb, 2013 | Pubmed ID: 23039284
The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner.
Molecular cancer research : MCR May, 2013 | Pubmed ID: 23399642
Control of the hippo pathway by Set7-dependent methylation of Yap.
Developmental cell Jul, 2013 | Pubmed ID: 23850191
An individual patient meta-analysis of five randomized trials assessing the effects of cardiac resynchronization therapy on morbidity and mortality in patients with symptomatic heart failure.
European heart journal Dec, 2013 | Pubmed ID: 23900696
PI3K Signaling in B Cell and T Cell Biology.
Frontiers in immunology , 2014 | Pubmed ID: 25404931
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.
Nature communications Feb, 2015 | Pubmed ID: 25644899
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.
Nature communications Nov, 2015 | Pubmed ID: 26525107
SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.
Developmental cell Apr, 2016 | Pubmed ID: 27046831
Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.
Journal of cell science 01, 2017 | Pubmed ID: 27199371
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling.
European journal of immunology Nov, 2016 | Pubmed ID: 27813071
The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse.
Journal of cell science 03, 2017 | Pubmed ID: 28167682
Predictors of short-term clinical response to cardiac resynchronization therapy.
European journal of heart failure Aug, 2017 | Pubmed ID: 28295869
Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility.
Scientific reports Sep, 2017 | Pubmed ID: 28900238
Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials.
Circulation. Heart failure Oct, 2017 | Pubmed ID: 29038172
The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis.
European journal of heart failure Jan, 2018 | Pubmed ID: 29314424
Imaging the Interactions Between B Cells and Antigen-Presenting Cells.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29388105
The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center.
Small GTPases Feb, 2018 | Pubmed ID: 29457987
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유