Marc Diederich

Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.

Natural compounds as regulators of the cancer cell metabolism.

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

Long and short non-coding RNAs as regulators of hematopoietic differentiation.

Metabolism and cancer: old and new players.

Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer.

Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases.

Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells.

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming.

From nature to bedside: pro-survival and cell death mechanisms as therapeutic targets in cancer treatment.

Plant-derived epigenetic modulators for cancer treatment and prevention.

Bis(4-hydroxy-2H-chromen-2-one): synthesis and effects on leukemic cell lines proliferation and NF-κB regulation.

Celecoxib prevents curcumin-induced apoptosis in a hematopoietic cancer cell model.

Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.

Epigenetic modulators from "The Big Blue": a treasure to fight against cancer.

5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.

Inhibitory effect of St. John׳s Wort oil macerates on TNFα-induced NF-κB activation and their fatty acid composition.

Plumbagin modulates leukemia cell redox status.

Methylenedioxy flavonoids: assessment of cytotoxic and anti-cancer potential in human leukemia cells.

Modulatory roles of glycolytic enzymes in cell death.

Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines.

Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis.

Energy restriction mimetic agents to target cancer cells: comparison between 2-deoxyglucose and thiazolidinediones.

Synthesis and bioactivity of novel amino-pyrazolopyridines.

P53 and Sirt1: routes of metabolism and genome stability.

Metabolism 2014--alterations of metabolic pathways as therapeutic targets.

Eurycomanone and eurycomanol from Eurycoma longifolia Jack as regulators of signaling pathways involved in proliferation, cell death and inflammation.

Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks.

Non-edible plants as an attractive source of compounds with chemopreventive potential.

Dual induction of mitochondrial apoptosis and senescence in chronic myelogenous leukemia by myrtucommulone A.

Hybrid curcumin compounds: a new strategy for cancer treatment.

Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target.

Roles of Apoptosis and Cellular Senescence in Cancer and Aging.

Breakthrough in tracking tumor erythropoietin receptor expression.

Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways.

A Survey of Marine Natural Compounds and Their Derivatives with Anti-cancer Activity Reported in 2012.

Bispecific antibodies: an innovative arsenal to hunt, grab and destroy cancer cells.

Effects of Natural Products on Mcl-1 Expression and Function.

Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential.

Signal Transducers and Activators of Transcription (STAT) Regulatory Networks in Marine Organisms: From Physiological Observations towards Marine Drug Discovery.

Epigenetic alterations as a universal feature of cancer hallmarks and a promising target for personalized treatments.

2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells.

Novel Pharmaceutical Approaches by Natural Compound-Derived Epigenetic Regulators: Epigenetic Readers, Writers and Erasers as Therapeutic Targets.

Perspectives in Medicinal Chemistry: DNA Methylation and Demethylation Mechanisms as Therapeutic Targets?

Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia.

Flavonoid glycosides from Olax mannii: Structure elucidation and effect on the nuclear factor kappa B pathway.

4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer.

Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer.

Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.

Non-canonical programmed cell death mechanisms triggered by natural compounds.

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

Cardiac glycosides: From molecular targets to immunogenic cell death.

4α-Methylated steroids with cytotoxic activity from the soft coral Litophyton mollis.

The Eighth Central European Conference "Chemistry towards Biology": Snapshot.

Natural Compound Histone Deacetylase Inhibitors (HDACi): Synergy with Inflammatory Signaling Pathway Modulators and Clinical Applications in Cancer.

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

Metabolomic Tools to Assess the Chemistry and Bioactivity of Endophytic Aspergillus Strain.

Anti-proliferative, Cytotoxic and NF-ĸB Inhibitory Properties of Spiro(Lactone-Cyclohexanone) Compounds in Human Leukemia.

Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.

Anticancer and Immunogenic Properties of Cardiac Glycosides.

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways.

The Forty-Sixth Euro Congress on Drug Synthesis and Analysis: Snapshot .

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.

Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer.

The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition.

Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy.

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.

Biotinylation enhances the anticancer effects of 15d‑PGJ2 against breast cancer cells.

Autophagy as a pharmacological target in hematopoiesis and hematological disorders.

Natural scaffolds in anticancer therapy and precision medicine.