Regenerative Medicine Research
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Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction.
American heart journal Sep, 2009 | Pubmed ID: 19699857
LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital , 2010 | Pubmed ID: 20844613
Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial.
JAMA : the journal of the American Medical Association Nov, 2011 | Pubmed ID: 22084195
Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure: The FOCUS-CCTRN Trial.
JAMA : the journal of the American Medical Association Mar, 2012 | Pubmed ID: 22447880
Effects of myocardial infarction on the distribution and transport of nutrients and oxygen in porcine myocardium.
Journal of biomechanical engineering Oct, 2012 | Pubmed ID: 23083196
Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.
JAMA : the journal of the American Medical Association Dec, 2012 | Pubmed ID: 23129008
Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN).
Circulation Apr, 2013 | Pubmed ID: 23588961
Building solutions for cardiovascular disease in women.
Texas Heart Institute journal , 2013 | Pubmed ID: 23914020
Optimizing recellularization of whole decellularized heart extracellular matrix.
PloS one , 2014 | Pubmed ID: 24587354
Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices.
Circulation Jun, 2014 | Pubmed ID: 24682346
Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats.
Nature communications 04, 2014 | Pubmed ID: 24736316
Ethics of bioengineering organs and tissues.
Expert opinion on biological therapy Jul, 2014 | Pubmed ID: 24792885
Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.
Circulation research May, 2014 | Pubmed ID: 24812350
Automated decellularization of intact, human-sized lungs for tissue engineering.
Tissue engineering. Part C, Methods Jan, 2015 | Pubmed ID: 24826875
Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.
Circulation research Oct, 2014 | Pubmed ID: 25136078
Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial.
Circulation research Jan, 2015 | Pubmed ID: 25406300
Rationale and design for PACE: patients with intermittent claudication injected with ALDH bright cells.
American heart journal Nov, 2014 | Pubmed ID: 25440794
Recruiting for Acute Myocardial Infarction Cell Therapy Trials: Challenges and Best Practices for the CCTRN.
Clinical researcher (Alexandria, Va.) Aug, 2014 | Pubmed ID: 25848636
Acellular human heart matrix: A critical step toward whole heart grafts.
Biomaterials Aug, 2015 | Pubmed ID: 26005766
Changing of the guard?
European heart journal Jul, 2015 | Pubmed ID: 26022009
Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial.
Cell transplantation , 2016 | Pubmed ID: 26590374
Orthotopic transplantation of a tissue engineered diaphragm in rats.
Biomaterials Jan, 2016 | Pubmed ID: 26618750
Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges.
Hypertension (Dallas, Tex. : 1979) May, 2016 | Pubmed ID: 26975706
Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts.
Biomaterials 08, 2016 | Pubmed ID: 27179434
Data from acellular human heart matrix.
Data in brief Sep, 2016 | Pubmed ID: 27331090
Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial.
American heart journal 09, 2016 | Pubmed ID: 27595689
Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials.
Basic research in cardiology 01, 2017 | Pubmed ID: 27882430
Inverted orientation improves decellularization of whole porcine hearts.
Acta biomaterialia 02, 2017 | Pubmed ID: 27884776
Maximizing Cardiac Repair: Should We Focus on the Cells or on the Matrix?
Circulation research 01, 2017 | Pubmed ID: 28057787
Optimized method for isolating highly purified and functional porcine aortic endothelial and smooth muscle cells.
Journal of cellular physiology Nov, 2017 | Pubmed ID: 28059438
Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
Circulation Apr, 2017 | Pubmed ID: 28209728
Response to letter to Editor "Comment on 'Inverted orientation improves decellularization of whole porcine hearts' by Lee et al."
Acta biomaterialia 04, 2017 | Pubmed ID: 28232256
Bioengineering Hearts: Simple yet Complex.
Current stem cell reports , 2017 | Pubmed ID: 28261549
The ubiquitin-proteasome system: A potential therapeutic target for heart failure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Jul, 2017 | Pubmed ID: 28341100
Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function.
Circulation research Jun, 2017 | Pubmed ID: 28490433
Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.
Scientific reports Jun, 2017 | Pubmed ID: 28667255
Premature atherosclerosis in premenopausal women: Does cytokine balance play a role?
Medical hypotheses Nov, 2017 | Pubmed ID: 29150290
TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis.
Circulation research Feb, 2018 | Pubmed ID: 29208679
Texas Heart Institute International Symposium on Cardiovascular Regenerative Medicine.
Circulation research Jan, 2018 | Pubmed ID: 29348248
Recellularization of rat liver: An in vitro model for assessing human drug metabolism and liver biology.
PloS one , 2018 | Pubmed ID: 29377912
Mobilizing EPCs: It is not just an acute issue.
International journal of cardiology 04, 2018 | Pubmed ID: 29506705
Author Correction: Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.
Scientific reports Mar, 2018 | Pubmed ID: 29511207
Decellularized matrices in regenerative medicine.
Acta biomaterialia Jul, 2018 | Pubmed ID: 29702289
Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit Cardiac Stem Cells As Regenerative Therapy for Heart Failure).
Circulation research Jun, 2018 | Pubmed ID: 29703749
Progress in experimental and clinical subpulmonary assistance for Fontan circulation.
The Journal of thoracic and cardiovascular surgery Nov, 2018 | Pubmed ID: 29884497
Building a Total Bioartificial Heart: Harnessing Nature to Overcome the Current Hurdles.
Artificial organs Oct, 2018 | Pubmed ID: 30044011
Leadless multisite pacing: A feasibility study using wireless power transfer based on Langendorff rodent heart models.
Journal of cardiovascular electrophysiology Nov, 2018 | Pubmed ID: 30203520
Whole Cardiac Tissue Bioscaffolds.
Advances in experimental medicine and biology , 2018 | Pubmed ID: 30238367
What will it take before a bioengineered heart will be implanted in patients?
Current opinion in organ transplantation Dec, 2018 | Pubmed ID: 30247170
A Path Forward for Regenerative Medicine.
Circulation research Aug, 2018 | Pubmed ID: 30355250
Racial Disparities in CD34+ Cells and Their Influence on Cardiovascular Repair.
Circulation research Aug, 2018 | Pubmed ID: 30355257
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