Tomoharu Kuboyama
Division of Neuromedical Science,
Institute of Natural Medicine,
Division of Neuromedical Science, Institute of Natural Medicine
University of Toyama
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Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jun, 2006 | Pubmed ID: 16292329
Withanoside IV and its active metabolite, sominone, attenuate Abeta(25-35)-induced neurodegeneration.
The European journal of neuroscience Mar, 2006 | Pubmed ID: 16553605
Current and future therapeutic strategies for functional repair of spinal cord injury.
Pharmacology & therapeutics Oct, 2011 | Pubmed ID: 21640756
Kamikihi-to (KKT) rescues axonal and synaptic degeneration associated with memory impairment in a mouse model of Alzheimer's disease, 5XFAD.
The International journal of neuroscience Dec, 2011 | Pubmed ID: 21770858
Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.
Scientific reports , 2012 | Pubmed ID: 22837815
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin.
British journal of pharmacology Feb, 2013 | Pubmed ID: 22978525
Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration.
Experimental neurology Oct, 2013 | Pubmed ID: 23797153
Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases.
Biological & pharmaceutical bulletin , 2014 | Pubmed ID: 24882401
New reliable scoring system, Toyama mouse score, to evaluate locomotor function following spinal cord injury in mice.
BMC research notes Jun, 2014 | Pubmed ID: 24890391
Comparing the effects of kamikihito in Japan and kami-guibi-tang in Korea on memory enhancement: working towards the development of a global study.
Phytotherapy research : PTR Mar, 2015 | Pubmed ID: 25346293
Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage.
Neurobiology of aging May, 2015 | Pubmed ID: 25772059
Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth.
Scientific reports Jul, 2015 | Pubmed ID: 26170015
Active Constituents from Drynaria fortunei Rhizomes on the Attenuation of Aβ(25-35)-Induced Axonal Atrophy.
Journal of natural products Sep, 2015 | Pubmed ID: 26299900
The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury.
Frontiers in pharmacology , 2015 | Pubmed ID: 26834638
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.
The Journal of biological chemistry 01, 2017 | Pubmed ID: 27941025
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Scientific reports Aug, 2017 | Pubmed ID: 28819194
Polygalae Radix Extract Prevents Axonal Degeneration and Memory Deficits in a Transgenic Mouse Model of Alzheimer's Disease.
Frontiers in pharmacology , 2017 | Pubmed ID: 29184495
Author Correction: HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Scientific reports Apr, 2018 | Pubmed ID: 29703924
Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice.
Frontiers in pharmacology , 2018 | Pubmed ID: 29867458
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