Center for Translational Systems Biology and Department of Neurology
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Strategies for mapping the binding site of the serotonin 5-HT2A receptor.
Methods in enzymology , 2002 | Pubmed ID: 11665561
Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction.
Methods in enzymology , 2002 | Pubmed ID: 11665639
Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays.
Nucleic acids research May, 2002 | Pubmed ID: 12000853
Coupling of GnRH concentration and the GnRH receptor-activated gene program.
Molecular endocrinology (Baltimore, Md.) Jun, 2002 | Pubmed ID: 12040003
Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12145300
Validated genomic approach to study differentially expressed genes in complex tissues.
Neurochemical research Oct, 2002 | Pubmed ID: 12462402
Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy.
Molecular pharmacology Jan, 2003 | Pubmed ID: 12488534
Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines.
The Biochemical journal Jul, 2003 | Pubmed ID: 12683952
Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor.
The Journal of biological chemistry Nov, 2003 | Pubmed ID: 12970364
Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2003 | Pubmed ID: 14523084
Structure of the GnRH receptor-stimulated signaling network: insights from genomics.
Frontiers in neuroendocrinology Jul, 2003 | Pubmed ID: 14596811
Focused microarray analysis.
Methods (San Diego, Calif.) Dec, 2003 | Pubmed ID: 14597315
Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15078887
Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression.
Neurochemical research Jun, 2004 | Pubmed ID: 15176466
Genomics view of gonadotrope signaling circuits.
Trends in endocrinology and metabolism: TEM Sep, 2004 | Pubmed ID: 15350605
Mutational analysis of the serotonin receptor 5HT2c in severe early-onset human obesity.
Canadian journal of physiology and pharmacology Jun, 2004 | Pubmed ID: 15381968
Epsilon-sarcoglycan immunoreactivity and mRNA expression in mouse brain.
The Journal of comparative neurology Jan, 2005 | Pubmed ID: 15612018
CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis.
Brain : a journal of neurology May, 2005 | Pubmed ID: 15774504
Acute induction of gene expression in brain and liver by insulin-induced hypoglycemia.
Diabetes Apr, 2005 | Pubmed ID: 15793232
Teaching resources. G-protein-coupled receptors.
Science's STKE : signal transduction knowledge environment Apr, 2005 | Pubmed ID: 15827322
Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2005 | Pubmed ID: 15958750
Transcript profiling of immediate early genes reveals a unique role for activating transcription factor 3 in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone.
Molecular endocrinology (Baltimore, Md.) Oct, 2005 | Pubmed ID: 15961508
Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridization.
Nucleic acids research , 2005 | Pubmed ID: 16224100
Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo.
The Journal of allergy and clinical immunology Dec, 2005 | Pubmed ID: 16337454
The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells.
The Journal of clinical investigation May, 2006 | Pubmed ID: 16604194
Influenza virus evades innate and adaptive immunity via the NS1 protein.
Journal of virology Jul, 2006 | Pubmed ID: 16775317
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.
Science (New York, N.Y.) Jul, 2006 | Pubmed ID: 16873667
Mixed analog/digital gonadotrope biosynthetic response to gonadotropin-releasing hormone.
The Journal of biological chemistry Oct, 2006 | Pubmed ID: 16916798
p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition.
The Journal of biological chemistry Dec, 2006 | Pubmed ID: 17060322
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.
Neuron Feb, 2007 | Pubmed ID: 17270739
Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats.
Journal of andrology Jul-Aug, 2007 | Pubmed ID: 17287459
Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription.
Journal of molecular endocrinology Feb, 2007 | Pubmed ID: 17293449
BioPP: a tool for web-publication of biological networks.
BMC bioinformatics , 2007 | Pubmed ID: 17519033
Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells.
Nucleic acids research , 2007 | Pubmed ID: 17675303
Noise propagation and scaling in regulation of gonadotrope biosynthesis.
Biophysical journal Dec, 2007 | Pubmed ID: 17720728
Time and length scales of autocrine signals in three dimensions.
Biophysical journal Sep, 2007 | Pubmed ID: 17720734
Identification of a serotonin/glutamate receptor complex implicated in psychosis.
Nature Mar, 2008 | Pubmed ID: 18297054
Getting started in biological pathway construction and analysis.
PLoS computational biology Feb, 2008 | Pubmed ID: 18463709
Cell-to-cell communication: time and length scales of ligand internalization in cultures of suspended cells.
The Journal of chemical physics Jun, 2008 | Pubmed ID: 18554059
Receptor pair for schizophrenia.
Pediatric research Jul, 2008 | Pubmed ID: 18574404
A comprehensive evaluation of human plasmacytoid dendritic cells using small volumes of human blood.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research Aug, 2008 | Pubmed ID: 18729740
Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus.
PLoS pathogens Oct, 2008 | Pubmed ID: 18974865
Antiviral-activated dendritic cells: a paracrine-induced response state.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2008 | Pubmed ID: 18981106
SOME STEP-DOWN PROCEDURES CONTROLLING THE FALSE DISCOVERY RATE UNDER DEPENDENCE.
Statistica Sinica , 2008 | Pubmed ID: 19018297
Psychedelics and schizophrenia.
Trends in neurosciences Apr, 2009 | Pubmed ID: 19269047
Agonist-trafficking and hallucinogens.
Current medicinal chemistry , 2009 | Pubmed ID: 19275609
Microtranscriptome regulation by gonadotropin-releasing hormone.
Molecular and cellular endocrinology Apr, 2009 | Pubmed ID: 19356622
Model of autocrine/paracrine signaling in epithelial layer: geometrical regulation of intercellular communication.
The journal of physical chemistry. B Aug, 2009 | Pubmed ID: 19601596
Group II metabotropic glutamate receptors and schizophrenia.
Cellular and molecular life sciences : CMLS Dec, 2009 | Pubmed ID: 19707855
Multiple testing and its applications to microarrays.
Statistical methods in medical research Dec, 2009 | Pubmed ID: 20048384
Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells.
Biophysical journal Feb, 2010 | Pubmed ID: 20159146
Antiviral response dictated by choreographed cascade of transcription factors.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2010 | Pubmed ID: 20164420
Coregulation mapping based on individual phenotypic variation in response to virus infection.
Immunome research , 2010 | Pubmed ID: 20298589
Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows.
PLoS computational biology Jun, 2010 | Pubmed ID: 20585619
Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase.
Molecular endocrinology (Baltimore, Md.) Sep, 2010 | Pubmed ID: 20592162
Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics.
CNS & neurological disorders drug targets Nov, 2010 | Pubmed ID: 20632964
Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study.
Journal of virology Nov, 2010 | Pubmed ID: 20739535
Validation of efficient high-throughput plasmid and siRNA transfection of human monocyte-derived dendritic cells without cell maturation.
Journal of immunological methods Dec, 2010 | Pubmed ID: 20875421
Signaling network of dendritic cells in response to pathogens: a community-input supported knowledgebase.
BMC systems biology , 2010 | Pubmed ID: 20929569
Misty Mountain clustering: application to fast unsupervised flow cytometry gating.
BMC bioinformatics , 2010 | Pubmed ID: 20932336
RNA and DNA microarrays.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 20967621
Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists.
Neuroscience letters Apr, 2011 | Pubmed ID: 21276828
Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells.
PloS one , 2011 | Pubmed ID: 21347441
Differential gene expression in patients with amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases Jul, 2011 | Pubmed ID: 21375368
Characterization of a MAPK scaffolding protein logic gate in gonadotropes.
Molecular endocrinology (Baltimore, Md.) Jun, 2011 | Pubmed ID: 21436256
Improved compensation in flow cytometry by multivariable optimization.
Cytometry. Part A : the journal of the International Society for Analytical Cytology May, 2011 | Pubmed ID: 21485003
Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors.
Neuropharmacology Sep, 2011 | Pubmed ID: 21645528
Authors response to correspondence about an improved compensation method.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Dec, 2011 | Pubmed ID: 22065546
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs.
Cell Nov, 2011 | Pubmed ID: 22118459
Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes.
Molecular and cellular endocrinology Mar, 2012 | Pubmed ID: 22127306
Multi-scale stochastic simulation of diffusion-coupled agents and its application to cell culture simulation.
PloS one , 2011 | Pubmed ID: 22216238
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