Division of Hematology-Oncology,
Beth Israel Deaconess Medical Center,
Department of Medicine,
Division of Hematology-Oncology, Beth Israel Deaconess Medical Center,
Department of Medicine, Beth Israel Deaconess Medical Center
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Targeted disruption of the PDZK1 gene by homologous recombination.
Molecular and cellular biology Feb, 2003 | Pubmed ID: 12556478
Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14551195
Evaluation of p53 mutations in premalignant esophageal lesions and esophageal adenocarcinoma using laser capture microdissection.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Nov, 2004 | Pubmed ID: 15257314
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis.
Biochimica et biophysica acta May, 2008 | Pubmed ID: 18342019
Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18544532
Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1.
The Journal of biological chemistry Feb, 2009 | Pubmed ID: 19116202
Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.
PloS one Dec, 2009 | Pubmed ID: 19956623
In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1.
The Journal of biological chemistry Nov, 2010 | Pubmed ID: 20739281
Identification of the PDZ3 domain of the adaptor protein PDZK1 as a second, physiologically functional binding site for the C terminus of the high density lipoprotein receptor scavenger receptor class B type I.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21602281
Molecular analysis of the prostacyclin receptor's interaction with the PDZ1 domain of its adaptor protein PDZK1.
PloS one , 2013 | Pubmed ID: 23457445
Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI).
The Journal of biological chemistry Jul, 2013 | Pubmed ID: 23720744
Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease.
American journal of physiology. Heart and circulatory physiology 12, 2016 | Pubmed ID: 27694217
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