Department of Pharmacology and Experimental Neuroscience
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Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2002 | Pubmed ID: 11937550
Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2003 | Pubmed ID: 14534250
OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis.
Journal of neuroimmunology May, 2004 | Pubmed ID: 15081264
Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2004 | Pubmed ID: 15187141
Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis.
Glia Dec, 2005 | Pubmed ID: 16078235
Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2005 | Pubmed ID: 16162919
Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase.
Toxicology and applied pharmacology Jul, 2006 | Pubmed ID: 16443250
CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2010 | Pubmed ID: 20495069
Nano-NRTIs: efficient inhibitors of HIV type-1 in macrophages with a reduced mitochondrial toxicity.
Antiviral chemistry & chemotherapy Oct, 2010 | Pubmed ID: 21045256
Loss of neuronal integrity during progressive HIV-1 infection of humanized mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2011 | Pubmed ID: 21368026
IL-23 in infections, inflammation, autoimmunity and cancer: possible role in HIV-1 and AIDS.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Mar, 2012 | Pubmed ID: 21947740
Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders?
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Jan, 2012 | Pubmed ID: 22222956
Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice.
International journal of nanomedicine , 2012 | Pubmed ID: 22745537
Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice.
AIDS (London, England) Nov, 2012 | Pubmed ID: 22824628
Antiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection.
Biomaterials May, 2013 | Pubmed ID: 23403120
Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Dec, 2013 | Pubmed ID: 23702663
Improved visualization of neuronal injury following glial activation by manganese enhanced MRI.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Sep, 2013 | Pubmed ID: 23729245
Nano-NRTIs demonstrate low neurotoxicity and high antiviral activity against HIV infection in the brain.
Nanomedicine : nanotechnology, biology, and medicine Jan, 2014 | Pubmed ID: 23845925
Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice.
The American journal of pathology Jan, 2014 | Pubmed ID: 24200850
Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations.
Biomaterials Feb, 2015 | Pubmed ID: 25522973
Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice.
Molecular neurodegeneration Dec, 2014 | Pubmed ID: 25523827
Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice.
Molecular neurobiology 07, 2016 | Pubmed ID: 26063593
Liver-targeted antiviral peptide nanocomplexes as potential anti-HCV therapeutics.
Biomaterials Nov, 2015 | Pubmed ID: 26298393
Influence of age, irradiation and humanization on NSG mouse phenotypes.
Biology open Sep, 2015 | Pubmed ID: 26353862
The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy.
Nanomedicine : nanotechnology, biology, and medicine Jan, 2016 | Pubmed ID: 26472049
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
AIDS research and human retroviruses Feb, 2016 | Pubmed ID: 26670361
Simple and reliable genotyping protocol for mouse Prkdc(SCID) mutation.
Journal of immunological methods Apr, 2016 | Pubmed ID: 26851521
Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice.
Scientific reports 05, 2016 | Pubmed ID: 27241024
Neuropharmacologic Approaches to Restore the Brain's Microenvironment.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 09, 2016 | Pubmed ID: 27352074
Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18.
Alcoholism, clinical and experimental research 11, 2016 | Pubmed ID: 27716962
A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy.
Retrovirology 03, 2017 | Pubmed ID: 28279181
Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection.
Scientific reports 08, 2017 | Pubmed ID: 28852071
Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains.
Disease models & mechanisms 12, 2017 | Pubmed ID: 29084769
Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice.
Biology open Feb, 2018 | Pubmed ID: 29361613
Creation of a long-acting nanoformulated dolutegravir.
Nature communications 02, 2018 | Pubmed ID: 29402886
Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice.
The Journal of pharmacology and experimental therapeutics 05, 2018 | Pubmed ID: 29476044
Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice.
Journal of neurovirology Aug, 2018 | Pubmed ID: 29594983
Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol as a Second Hit.
Biomolecules 10, 2018 | Pubmed ID: 30322122
Liver as a target of human immunodeficiency virus infection.
World journal of gastroenterology Nov, 2018 | Pubmed ID: 30479460
Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection.
BMC immunology 01, 2019 | Pubmed ID: 30616506
Human immunodeficiency virus and hepatotropic viruses co-morbidities as the inducers of liver injury progression.
World journal of gastroenterology Jan, 2019 | Pubmed ID: 30700937
Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice.
Molecular neurodegeneration 03, 2019 | Pubmed ID: 30832693
Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice.
Frontiers in immunology , 2019 | Pubmed ID: 30873181
Acetaldehyde suppresses the display of HBV-MHC class I complexes on HBV-expressing hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology Aug, 2019 | Pubmed ID: 31141391
Small molecule ONC201 inhibits HIV-1 replication in macrophages via FOXO3a and TRAIL.
Antiviral research Aug, 2019 | Pubmed ID: 31158413
Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.
Nature communications 07, 2019 | Pubmed ID: 31266936
Eluted 25-hydroxyvitamin D from radially aligned nanofiber scaffolds enhances cathelicidin production while reducing inflammatory response in human immune system-engrafted mice.
Acta biomaterialia Aug, 2019 | Pubmed ID: 31386930
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