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Mass spectrometry-based methods for phosphorylation site mapping of hyperphosphorylated proteins applied to Net1, a regulator of exit from mitosis in yeast.
Molecular & cellular proteomics : MCP Mar, 2002 | Pubmed ID: 12096118
Improved sensitivity for phosphopeptide mapping using capillary column HPLC and microionspray mass spectrometry: comparative phosphorylation site mapping from gel-derived proteins.
Analytical chemistry Jul, 2002 | Pubmed ID: 12141686
N-Terminal peptide labeling strategy for incorporation of isotopic tags: a method for the determination of site-specific absolute phosphorylation stoichiometry.
Rapid communications in mass spectrometry : RCM , 2002 | Pubmed ID: 12478578
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.
Oncogene Jun, 2004 | Pubmed ID: 15107835
Selective detection of glycopeptides on ion trap mass spectrometers.
Analytical chemistry Jun, 2004 | Pubmed ID: 15167790
Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus.
Science (New York, N.Y.) Jul, 2004 | Pubmed ID: 15273393
Place of pattern in proteomic biomarker discovery.
Journal of proteome research Jul-Aug, 2005 | Pubmed ID: 16083265
Mapping posttranslational modifications of proteins by MS-based selective detection: application to phosphoproteomics.
Methods in enzymology , 2005 | Pubmed ID: 16413312
Systematic identification of human mitochondrial disease genes through integrative genomics.
Nature genetics May, 2006 | Pubmed ID: 16582907
PEPPeR, a platform for experimental proteomic pattern recognition.
Molecular & cellular proteomics : MCP Oct, 2006 | Pubmed ID: 16857664
Protein biomarker discovery and validation: the long and uncertain path to clinical utility.
Nature biotechnology Aug, 2006 | Pubmed ID: 16900146
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.
Current biology : CB Sep, 2006 | Pubmed ID: 16919458
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Science (New York, N.Y.) Sep, 2006 | Pubmed ID: 17008526
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Molecular cell Mar, 2007 | Pubmed ID: 17386266
Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.
The EMBO journal May, 2007 | Pubmed ID: 17446864
Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.
Molecular & cellular proteomics : MCP Dec, 2007 | Pubmed ID: 17939991
Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification.
Molecular & cellular proteomics : MCP Oct, 2008 | Pubmed ID: 18534968
A mitochondrial protein compendium elucidates complex I disease biology.
Cell Jul, 2008 | Pubmed ID: 18614015
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.
Molecular systems biology , 2008 | Pubmed ID: 18682704
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury.
The Journal of clinical investigation Oct, 2008 | Pubmed ID: 18769631
Protein quantitation through targeted mass spectrometry: the way out of biomarker purgatory?
Clinical chemistry Nov, 2008 | Pubmed ID: 18957555
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
Nature biotechnology Jan, 2009 | Pubmed ID: 19098899
A human proteome detection and quantitation project.
Molecular & cellular proteomics : MCP May, 2009 | Pubmed ID: 19131327
Prediction of high-responding peptides for targeted protein assays by mass spectrometry.
Nature biotechnology Feb, 2009 | Pubmed ID: 19169245
Identifying the proteins to which small-molecule probes and drugs bind in cells.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19255428
Directed sample interrogation utilizing an accurate mass exclusion-based data-dependent acquisition strategy (AMEx).
Journal of proteome research Jun, 2009 | Pubmed ID: 19344186
Developing multiplexed assays for troponin I and interleukin-33 in plasma by peptide immunoaffinity enrichment and targeted mass spectrometry.
Clinical chemistry Jun, 2009 | Pubmed ID: 19372185
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.
PLoS biology May, 2009 | Pubmed ID: 19468302
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.
Nature biotechnology Jul, 2009 | Pubmed ID: 19561596
Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution.
Molecular & cellular proteomics : MCP Oct, 2009 | Pubmed ID: 19596694
Proteomic and genetic approaches identify Syk as an AML target.
Cancer cell Oct, 2009 | Pubmed ID: 19800574
Empirical Bayes analysis of quantitative proteomics experiments.
PloS one , 2009 | Pubmed ID: 19829701
Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.
Molecular & cellular proteomics : MCP Feb, 2010 | Pubmed ID: 19837981
Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance.
Molecular & cellular proteomics : MCP Feb, 2010 | Pubmed ID: 19858499
Introduction: Advances in protein analysis for the clinical laboratory.
Clinical chemistry Feb, 2010 | Pubmed ID: 19910505
Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry.
Journal of proteome research Feb, 2010 | Pubmed ID: 19921851
Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration.
Clinical chemistry Feb, 2010 | Pubmed ID: 20007858
Analytical validation of protein-based multiplex assays: a workshop report by the NCI-FDA interagency oncology task force on molecular diagnostics.
Clinical chemistry Feb, 2010 | Pubmed ID: 20007859
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
PLoS biology Dec, 2009 | Pubmed ID: 20016685
Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry.
Clinical chemistry Feb, 2010 | Pubmed ID: 20022980
Integration of proteomic-based tools for improved biomarkers of myocardial injury.
Clinical chemistry Feb, 2010 | Pubmed ID: 20022985
A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.
PLoS biology Jan, 2010 | Pubmed ID: 20126263
Optimizing performance of glycopeptide capture for plasma proteomics.
Journal of proteome research Apr, 2010 | Pubmed ID: 20235580
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
Molecular cancer research : MCR Jun, 2010 | Pubmed ID: 20501647
Metabolic signatures of exercise in human plasma.
Science translational medicine May, 2010 | Pubmed ID: 20505214
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2010 | Pubmed ID: 20616024
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization.
Molecular cell Oct, 2010 | Pubmed ID: 20932473
Effect of collision energy optimization on the measurement of peptides by selected reaction monitoring (SRM) mass spectrometry.
Analytical chemistry Dec, 2010 | Pubmed ID: 21090646
Overview of peptide and protein analysis by mass spectrometry.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] Nov, 2010 | Pubmed ID: 21104985
Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry.
Molecular & cellular proteomics : MCP Apr, 2011 | Pubmed ID: 21245105
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
The Journal of clinical investigation Apr, 2011 | Pubmed ID: 21403394
A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.
Nature biotechnology Jul, 2011 | Pubmed ID: 21685905
Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21746906
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature Jul, 2011 | Pubmed ID: 21753854
AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics.
Chemistry & biology Jul, 2011 | Pubmed ID: 21802010
Status and prospects for discovery and verification of new biomarkers of cardiovascular disease by proteomics.
Circulation research Aug, 2011 | Pubmed ID: 21817166
Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation.
Cell metabolism Sep, 2011 | Pubmed ID: 21907147
Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.
PloS one , 2011 | Pubmed ID: 21984943
Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22065222
Systematic discovery of TLR signaling components delineates viral-sensing circuits.
Cell Nov, 2011 | Pubmed ID: 22078882
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Molecular & cellular proteomics : MCP Dec, 2011 | Pubmed ID: 22159717
Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.
Molecular & cellular proteomics : MCP Dec, 2011 | Pubmed ID: 22199228
iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.
Molecular & cellular proteomics : MCP Dec, 2011 | Pubmed ID: 22210691
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22323609
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