Minetaro Arita

Characterization of the poliovirus 147S particle: new insights into poliovirus uncoating.

Characterization of in vitro and in vivo phenotypes of poliovirus type 1 mutants with reduced viral protein synthesis activity.

Circulation of type 1 vaccine-derived poliovirus in the Philippines in 2001.

Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys.

A Sabin 3-derived poliovirus recombinant contained a sequence homologous with indigenous human enterovirus species C in the viral polymerase coding region.

Quantitative analysis of poliomyelitis-like paralysis in mice induced by a poliovirus replicon.

Rapid genome sequencing of RNA viruses.

An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.

Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model.

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity.

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime.

Development of a reverse transcription-loop-mediated isothermal amplification (RT-LAMP) system for a highly sensitive detection of enterovirus in the stool samples of acute flaccid paralysis cases.

Development of a particle agglutination method with soluble virus receptor for identification of poliovirus.

A bifunctional anti-enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection.

Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.

Biochemical characterization of enterovirus 71 3D RNA polymerase.

Development of a poliovirus neutralization test with poliovirus pseudovirus for measurement of neutralizing antibody titer in human serum.

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites.