Division of Nephrology and Clinical Immunology
Rafael Kramann is Professor of Medicine and Chair of Nephro-Cardiology at RWTH Aachen University, Germany. He directs the Laboratory of Translational Kidney and Cardiovascular Research in the Department of Nephrology (www.kramannlab.com) at RWTH Aachen University and Erasmus Medical Center Rotterdam, NL and is board certified physician for internal medicine and nephrology. He received his MD in cardiology at RWTH Aachen University, Germany and his PhD in Cell Biology and Basic Research at Erasmus Medical Center, Rotterdam. He worked as a postdoc at Harvard Medical Schooln and Brigham and Brigham and Women´s Hospital with Benjamin Humphreys.
His basic and translational research focusses on understanding cardiovascular disease in chronic kidney disease patients and organ fibrosis. He integrates state of the art genetic fate tracing, CRISPR/Cas9 gene editing, single cells omic and systems biology technologies together with clinical datasets to identify novel therapeutic targets and develop targeted therapeutics for patients with organ fibrosis, vascular sclerosis and heart failure. His clinical research interests are focusing on biomarker discovery in fibrosis , novel treatment strategies in vascular calcification and early diagnosis of uremic cardiomyopathy. He has authored more than 65 primary research and review articles and he is recipient of various prestigous awards including the Grand Prize in the Harvard Innovation Lab Dean´s Health and Lifescience Challenge 2013 the Stanley Shaldon Award of the European Renal Association (ERA-EDTA) 2014, a European Research Council Starting Grant 2015, the Nils Alwall and Carl Ludwig Awards 2014 and 2015 of the German Society of Nephrology, the Bernd Tersteegen Award 2015 of the German Dialysis Association and the Desiderius Award of the Erasmus University in 2018.
Analysis of myocardial deformation based on ultrasonic pixel tracking to determine transmurality in chronic myocardial infarction.
European heart journal Nov, 2006 | Pubmed ID: 17035253
Myocardial deformation imaging based on ultrasonic pixel tracking to identify reversible myocardial dysfunction.
Journal of the American College of Cardiology Apr, 2008 | Pubmed ID: 18402903
Medical options to fight mortality in end-stage renal disease: a review of the literature.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Dec, 2012 | Pubmed ID: 23045427
Parathyroid hormone-related protein and regulation of cell survival in the kidney.
Kidney international May, 2013 | Pubmed ID: 23633047
Sclerostin as a potential novel biomarker for aortic valve calcification: an in-vivo and ex-vivo study.
The Journal of heart valve disease May, 2013 | Pubmed ID: 24151757
Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9.
Nature medicine Mar, 2016 | Pubmed ID: 26878232
Lack of evidence does not justify neglect: how can we address unmet medical needs in calciphylaxis?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 08, 2016 | Pubmed ID: 27005994
The new SFB/TRR219 Research Centre.
European heart journal Mar, 2018 | Pubmed ID: 29579229
Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease.
International journal of molecular sciences Feb, 2019 | Pubmed ID: 30791399
Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Scientific reports Mar, 2019 | Pubmed ID: 30872636
1Division of Nephrology and Clinical Immunology, University Hospital RWTH Aachen,
2III. Department of Medicine, University Medical Center, Hamburg-Eppendorf,
3Department of Nephrology, Monash Health,
4Division of Nephrology and Hypertension, Oregon Health and Science University,
5Renal Section, Veterans Affairs Portland Health Care System,
6, Fondation LeDucq Transatlantic Networks of Excellence,
7Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center
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