Christopher C. Ebmeier
Department of Molecular,
Cellular and Developmental Biology,
Department of Molecular, Cellular and Developmental Biology
University of Colorado
Chris Ebmeier received a BS in Biochemistry from the University of Nebraska-Lincoln. He spent several years in the Biotech industry developing manufacturing processes and analytical methods for therapeutic recombinant human hormone peptides. He next pursued graduate work in the lab of Dylan Taatjes at the University of Colorado Boulder receiving a PhD in Biochemistry. His graduate studies involved developing and applying proteomics technologies to investigate the mechanisms of regulated gene expression. Chris is currently working in the lab of William Old in the MCD Biology department at the University of Colorado Boulder, where he advances and promotes proteomics technologies for a wide array of projects.
CDK8 is a positive regulator of transcriptional elongation within the serum response network.
Nature structural & molecular biology Feb, 2010 | Pubmed ID: 20098423
Activator-Mediator binding regulates Mediator-cofactor interactions.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20534441
Mediator and cohesin connect gene expression and chromatin architecture.
Nature Sep, 2010 | Pubmed ID: 20720539
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.
PLoS biology Mar, 2011 | Pubmed ID: 21468301
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
Genes & development Dec, 2012 | Pubmed ID: 23249733
The Mediator complex and transcription regulation.
Critical reviews in biochemistry and molecular biology Nov-Dec, 2013 | Pubmed ID: 24088064
TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release.
Nature structural & molecular biology Oct, 2014 | Pubmed ID: 25173174
Licensing of yeast centrosome duplication requires phosphoregulation of sfi1.
PLoS genetics Oct, 2014 | Pubmed ID: 25340401
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH.
Molecular cell Sep, 2015 | Pubmed ID: 26340423
Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Nature Oct, 2015 | Pubmed ID: 26416749
Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics.
Cell reports Apr, 2016 | Pubmed ID: 27050516
A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate.
Journal of bacteriology 10, 2016 | Pubmed ID: 27501982
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.
Cell reports 08, 2017 | Pubmed ID: 28768201
Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Molecular & cellular proteomics : MCP 04, 2018 | Pubmed ID: 29255136
Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme.
PLoS genetics 08, 2018 | Pubmed ID: 30148850
A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission.
Cell 09, 2018 | Pubmed ID: 30220460
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.
Scientific reports Apr, 2019 | Pubmed ID: 31024071
Hidden resources in the genome restore PLP synthesis and robust growth after deletion of the essential gene .
Proceedings of the National Academy of Sciences of the United States of America Nov, 2019 | Pubmed ID: 31712440
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