Rajanikanth Vadigepalli

Single-Cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks Involved in the Central Circadian Clock.

PAINT: a promoter analysis and interaction network generation tool for gene regulatory network identification.

Erythroid-induced commitment of K562 cells results in clusters of differentially expressed genes enriched for specific transcription regulatory elements.

Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius.

The inflammatory and normal transcriptome of mouse bladder detrusor and mucosa.

Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling.

Epidermal growth factor receptor-induced circadian-time-dependent gene regulation in suprachiasmatic nucleus.

Bladder inflammatory transcriptome in response to tachykinins: neurokinin 1 receptor-dependent genes and transcription regulatory elements.

From promoter analysis to transcriptional regulatory network prediction using PAINT.

Dynamic transcriptomic response to acute hypertension in the nucleus tractus solitarius.

Transcriptional regulatory network analysis during epithelial-mesenchymal transformation of retinal pigment epithelium.

Temporal and functional profile of the transcriptional regulatory network in the early regenerative response to partial hepatectomy in the rat.

Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory network.

Adaptive transcriptional dynamics of A2 neurons and central cardiovascular control pathways.

Rapid temporal changes in the expression of a set of neuromodulatory genes during alcohol withdrawal in the dorsal vagal complex: molecular evidence of homeostatic disturbance.

Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei.

Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level.

Integrative gene regulatory network analysis reveals light-induced regional gene expression phase shift programs in the mouse suprachiasmatic nucleus.

Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats.

Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration.

Coordinated dynamic gene expression changes in the central nucleus of the amygdala during alcohol withdrawal.

Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.

MicroRNA profiling in lung cancer reveals new molecular markers for diagnosis.

Ethanol alters the balance of Sox2, Oct4, and Nanog expression in distinct subpopulations during differentiation of embryonic stem cells.

Ethanol diverts early neuronal differentiation trajectory of embryonic stem cells by disrupting the balance of lineage specifiers.

Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype.

Inputs drive cell phenotype variability.

Identifying functional gene regulatory network phenotypes underlying single cell transcriptional variability.

Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.

Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modelling.

MicroRNA network changes in the brain stem underlie the development of hypertension.

A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes.

Computational modeling of cytokine signaling in microglia.

In Vivo Zonal Variation and Liver Cell-Type Specific NF-κB Localization after Chronic Adaptation to Ethanol and following Partial Hepatectomy.

Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features.

Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes.

Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes.

Erratum to: Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes.

A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration.

A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration.

HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells.

Computational Modeling of Spatiotemporal Ca(2+) Signal Propagation Along Hepatocyte Cords.

Systemic leukotriene B receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat.

Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation.

Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats.

Pattern analysis uncovers a chronic ethanol-induced disruption of the switch-like dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration.

A data-driven modeling approach to identify disease-specific multi-organ networks driving physiological dysregulation.

Novel Influences of IL-10 on CNS Inflammation Revealed by Integrated Analyses of Cytokine Networks and Microglial Morphology.

Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders.

Introduction to the Virtual Issue Alcohol and Epigenetic Regulation: Do the Products of Alcohol Metabolism Drive Epigenetic Control of Gene Expression in Alcohol-Related Disorders?

SPSNet: subpopulation-sensitive network-based analysis of heterogeneous gene expression data.

Credibility, Replicability, and Reproducibility in Simulation for Biomedicine and Clinical Applications in Neuroscience.

Single-Cell Gene Expression Analysis Identifies Chronic Alcohol-Mediated Shift in Hepatocyte Molecular States After Partial Hepatectomy.

Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics.

Causality Analysis and Cell Network Modeling of Spatial Calcium Signaling Patterns in Liver Lobules.

Model-based virtual patient analysis of human liver regeneration predicts critical perioperative factors controlling the dynamic mode of response to resection.

Modeling the Dynamics of Human Liver Failure Post Liver Resection.

Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis.

A Novel Mouse Model of Acute-on-Chronic Cholestatic Alcoholic Liver Disease: A Systems Biology Comparison With Human Alcoholic Hepatitis.

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.

A Comprehensive Integrated Anatomical and Molecular Atlas of Rat Intrinsic Cardiac Nervous System.

Diurnal Patterns of Gene Expression in the Dorsal Vagal Complex and the Central Nucleus of the Amygdala - Non-rhythm-generating Brain Regions.

Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis.

Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension.

Credible practice of modeling and simulation in healthcare: ten rules from a multidisciplinary perspective.

Integrated Multiomics Reveals Glucose Use Reprogramming and Identifies a Novel Hexokinase in Alcoholic Hepatitis.

Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas.

Input-output signal processing plasticity of vagal motor neurons in response to cardiac ischemic injury.

Mapping the little brain at the heart by an interdisciplinary systems biology team.

A single cell transcriptomics map of paracrine networks in the intrinsic cardiac nervous system.

3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system.

Analyzing the relationships between city opioid deaths and socioeconomic factors.

Retinoic Acid Fluctuation Activates an Uneven, Direction-Dependent Network-Wide Robustness Response in Early Embryogenesis.

Dysregulation of miR-21-associated miRNA regulatory networks by chronic ethanol consumption impairs liver regeneration.

Single Cell Scale Neuronal and Glial Gene Expression and Putative Cell Phenotypes and Networks in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series.

A Spatial Model of Hepatic Calcium Signaling and Glucose Metabolism Under Autonomic Control Reveals Functional Consequences of Varying Liver Innervation Patterns Across Species.