Department of Medicine
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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
American journal of respiratory and critical care medicine Feb, 2017 | Pubmed ID: 27648837
Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 01, 2018 | Pubmed ID: 29158355
Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Circulation Jul, 2018 | Pubmed ID: 29431643
Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
Frontiers in physiology , 2018 | Pubmed ID: 30042687
Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
International journal of molecular sciences Sep, 2018 | Pubmed ID: 30213070
Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities.
Frontiers in cardiovascular medicine , 2018 | Pubmed ID: 30740395
Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
Circulation research 06, 2019 | Pubmed ID: 30922174
Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
Circulation research 08, 2019 | Pubmed ID: 31154939
Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
Comprehensive Physiology Mar, 2020 | Pubmed ID: 32163206
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
Circulation Mar, 2020 | Pubmed ID: 32192357
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Circulation research Jun, 2020 | Pubmed ID: 32216531
Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
Acta physiologica (Oxford, England) Apr, 2020 | Pubmed ID: 32339403
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