Health Science and Technologies Interdepartmental Center for Industrial Research (HST-ICIR)
Vito Antonio Baldassarro is a Junior Researcher at the Department of Veterinary Medical Sciences of the University of Bologna (Italy). He completed his Master Degree in Animal Biotechnolgy and his PhD in Molecular and Cellular Biology.
During his Master thesis he started working with human stem cells and induced pluripotent stem cells at the "Ecole Polytechnique Fédérale de Lausanne" (EPFL) in Switzerland. During his PhD and post docs he worked both at the Interdepartmental Center of the Industrial Research, of the University of Bologna, and at the Institute of Genetic and Molecular Biology of Strasbourg (France). During 10 years he started his specialization on primary cultures, in vitro models of pathological conditions and molecular biology studies of gene expression regulation, in a translational perspective.
Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.
BMC neuroscience Apr, 2013 | Pubmed ID: 23560952
From the multifactorial nature of Alzheimer`s disease to multitarget therapy: the contribution of the translational approach.
Current topics in medicinal chemistry , 2013 | Pubmed ID: 23931439
Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery.
World journal of stem cells Oct, 2013 | Pubmed ID: 24179610
In vitro exposure to very low-level laser modifies expression level of extracellular matrix protein RNAs and mitochondria dynamics in mouse embryonic fibroblasts.
BMC complementary and alternative medicine Mar, 2015 | Pubmed ID: 25886934
In Vitro Testing of Biomaterials for Neural Repair: Focus on Cellular Systems and High-Content Analysis.
BioResearch open access , 2016 | Pubmed ID: 27588220
REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer's disease mouse model.
Scientific reports 10, 2016 | Pubmed ID: 27775040
Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.
Disease models & mechanisms 05, 2017 | Pubmed ID: 28237964
Age-Related Changes of the Neurovascular Unit in the Cerebral Cortex of Alzheimer Disease Mouse Models: A Neuroanatomical and Molecular Study.
Journal of neuropathology and experimental neurology 02, 2019 | Pubmed ID: 30629191
The role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cells.
Stem cell research 05, 2019 | Pubmed ID: 31022610
New Insights into the Hepcidin-Ferroportin Axis and Iron Homeostasis in iPSC-Derived Cardiomyocytes from Friedreich's Ataxia Patient.
Oxidative medicine and cellular longevity , 2019 | Pubmed ID: 31049138
Possible Strategies to Optimize a Biomarker Discovery Approach to Correlate with Neurological Outcome in Patients with Spinal Cord Injury: A Pilot Study.
Journal of neurotrauma 02, 2020 | Pubmed ID: 31215324
A novel mutation in gene causes a severe neurodevelopmental delay due to mitochondrial dysfunction with complex I impairments and altered pyruvate metabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 10, 2019 | Pubmed ID: 31314595
Differential effects of glucose deprivation on the survival of fetal versus adult neural stem cells-derived oligodendrocyte precursor cells.
Glia 05, 2020 | Pubmed ID: 31755592
White Matter and Neuroprotection in Alzheimer's Dementia.
Molecules (Basel, Switzerland) Jan, 2020 | Pubmed ID: 31979414
Oligodendrocytes in a dish for the drug discovery pipeline: the risk of oversimplification.
Neural regeneration research Feb, 2021 | Pubmed ID: 32859780
Thyroid Hormone Signaling in Embryonic Stem Cells: Crosstalk with the Retinoic Acid Pathway.
International journal of molecular sciences Nov, 2020 | Pubmed ID: 33255695
Time-Course Changes of Extracellular Matrix Encoding Genes Expression Level in the Spinal Cord Following Contusion Injury-A Data-Driven Approach.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33572341
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