Departments of Research Pathology
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The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.
eLife 07, 2016 | Pubmed ID: 27410477
Multiplexed ion beam imaging analysis for quantitation of protein expression in cancer tissue sections.
Laboratory investigation; a journal of technical methods and pathology 08, 2017 | Pubmed ID: 28553935
Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2017 | Pubmed ID: 28606920
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research.
Advances in anatomic pathology Sep, 2017 | Pubmed ID: 28777142
Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.
Advances in anatomic pathology Nov, 2017 | Pubmed ID: 28777143
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.
Nature 02, 2018 | Pubmed ID: 29443960
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma.
eLife 05, 2019 | Pubmed ID: 31144617
CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.
Cancer research 08, 2019 | Pubmed ID: 31182547
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Cell 08, 2019 | Pubmed ID: 31353221
A Phase I Study of DLYE5953A, an Anti-LY6E Antibody Covalently Linked to Monomethyl Auristatin E, in Patients with Refractory Solid Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2020 | Pubmed ID: 32694157
Charles A. Havnar1,
Oliver Zill2,
Jeff Eastham1,
Jeffrey Hung1,
Manana Javey3,
Emmanuel Naouri3,
Jennifer Giltnane1,
Justin M. Balko4,
Andrew Wallace2,
Nicolas Lounsbury2,
Daniel Oreper2,
Sarajane Saturnio1,
G-Y Yang5,
Amy A. Lo1
1Departments of Research Pathology, Genentech,
2Bioinformatics & Computational Biology, Genentech,
3, Roche Sequencing Solutions, Hacienda Drive,
4Department of Medicine, Vanderbilt University Medical Center, Medical Center Drive,
5Department of Pathology, Northwestern University, Feinberg School of Medicine
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