Department of Biosciences
Basic research aspects: My research activities focuses on understanding the mechanism of allergic sensitization induced by pollen allergens, the induction of immune tolerance, and the molecular/immunological characterization of allergens.
Translational research: Development of novel therapeutic approaches for the treatment of (pollen) allergies
Main Research Areas
Molecular Biology, Molecular and Cellular Allergology, Immunology
Allergy diagnosis and treatment
Recombinant molecules and physico-chemical characterization
Mimetic peptide characterization
Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.
International journal of molecular sciences , | Pubmed ID: 29035299
Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity.
The Journal of allergy and clinical immunology , | Pubmed ID: 29157946
Context matters: T2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity.
The Journal of allergy and clinical immunology , | Pubmed ID: 29782896
Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of AIT.
Clinical and translational allergy , | Pubmed ID: 30338052
Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading.
Frontiers in physiology , | Pubmed ID: 30745882
Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity.
Allergy , | Pubmed ID: 31230350
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice.
Allergy , | Pubmed ID: 31750952
N-terminal peptide deletion influences immunological and structural features of Blo t 5.
Allergy , | Pubmed ID: 31916257
Defining biomarkers to predict symptoms in subjects with and without allergy under natural pollen exposure.
The Journal of allergy and clinical immunology , | Pubmed ID: 32272131
A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology , | Pubmed ID: 32314444
Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family.
Current allergy and asthma reports 05, 2020 | Pubmed ID: 32430735
Initiating pollen sensitization - complex source, complex mechanisms.
Clinical and translational allergy , 2020 | Pubmed ID: 32884636
Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet v 1 Variant.
Frontiers in immunology , 2020 | Pubmed ID: 33013894
Ragweed plants grown under elevated CO levels produce pollen which elicit stronger allergic lung inflammation.
Allergy 06, 2021 | Pubmed ID: 33037672
Identification and Physicochemical Characterization of a New Allergen from .
International journal of molecular sciences Dec, 2020 | Pubmed ID: 33371317
IgE-cross-blocking antibodies to Fagales following sublingual immunotherapy with recombinant Bet v 1.
Allergy Mar, 2021 | Pubmed ID: 33724487
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