Department of Biomedical Engineering
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Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone.
Journal of biomechanics Jun, 2005 | Pubmed ID: 15863107
The influence of cortical end-plate on broadband ultrasound attenuation measurements at the human calcaneus using scanning confocal ultrasound.
The Journal of the Acoustical Society of America Sep, 2005 | Pubmed ID: 16240838
The effects of embedding material, loading rate and magnitude, and penetration depth in nanoindentation of trabecular bone.
Journal of biomedical materials research. Part A Oct, 2006 | Pubmed ID: 16758456
The effects of frequency-dependent dynamic muscle stimulation on inhibition of trabecular bone loss in a disuse model.
Bone Dec, 2008 | Pubmed ID: 18757047
Biomineralization of a self-assembled extracellular matrix for bone tissue engineering.
Tissue engineering. Part A Feb, 2009 | Pubmed ID: 18759666
Characterization of the trabecular bone structure using frequency modulated ultrasound pulse.
The Journal of the Acoustical Society of America Jun, 2009 | Pubmed ID: 19507988
Complementary effects of multi-protein components on biomineralization in vitro.
Journal of structural biology Apr, 2010 | Pubmed ID: 20035875
Mechanical signals as anabolic agents in bone.
Nature reviews. Rheumatology Jan, 2010 | Pubmed ID: 20046206
Skeletal nutrient vascular adaptation induced by external oscillatory intramedullary fluid pressure intervention.
Journal of orthopaedic surgery and research Mar, 2010 | Pubmed ID: 20222973
Alteration of contraction-to-rest ratio to optimize trabecular bone adaptation induced by dynamic muscle stimulation.
Bone Feb, 2011 | Pubmed ID: 20850577
A new algorithm for spatial impulse response of rectangular planar transducers.
Ultrasonics Feb, 2011 | Pubmed ID: 20863543
Mitigation of bone loss with ultrasound induced dynamic mechanical signals in an OVX induced rat model of osteopenia.
Bone May, 2011 | Pubmed ID: 21241838
Extension of the distributed point source method for ultrasonic field modeling.
Ultrasonics Jul, 2011 | Pubmed ID: 21269654
Postural instability caused by extended bed rest is alleviated by brief daily exposure to low magnitude mechanical signals.
Gait & posture Mar, 2011 | Pubmed ID: 21273076
Effects of phase cancellation and receiver aperture size on broadband ultrasonic attenuation for trabecular bone in vitro.
Ultrasound in medicine & biology Dec, 2011 | Pubmed ID: 22033134
Prediction of trabecular bone principal structural orientation using quantitative ultrasound scanning.
Journal of biomechanics Jun, 2012 | Pubmed ID: 22560370
Mechanobiological modulation of cytoskeleton and calcium influx in osteoblastic cells by short-term focused acoustic radiation force.
PloS one , 2012 | Pubmed ID: 22701628
Dynamic hydraulic flow stimulation on mitigation of trabecular bone loss in a rat functional disuse model.
Bone Oct, 2012 | Pubmed ID: 22820398
Frequency Specific Ultrasound Attenuation is Sensitive to Trabecular Bone Structure.
Ultrasound in medicine & biology Sep, 2012 | Pubmed ID: 22975035
The mechanical consequences of load bearing in the equine third metacarpal across speed and gait: the nonuniform distributions of normal strain, shear strain, and strain energy density.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2013 | Pubmed ID: 23355269
Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering.
Biomacromolecules Mar, 2013 | Pubmed ID: 23405887
Reversal of the detrimental effects of simulated microgravity on human osteoblasts by modified low intensity pulsed ultrasound.
Ultrasound in medicine & biology May, 2013 | Pubmed ID: 23453382
Tungsten disulfide nanotubes reinforced biodegradable polymers for bone tissue engineering.
Acta biomaterialia Sep, 2013 | Pubmed ID: 23727293
Dynamic hydraulic fluid stimulation regulated intramedullary pressure.
Bone Nov, 2013 | Pubmed ID: 23895997
Prediction of trabecular bone qualitative properties using scanning quantitative ultrasound.
Acta astronautica Nov, 2013 | Pubmed ID: 23976803
Enhancement of osteogenic differentiation and proliferation in human mesenchymal stem cells by a modified low intensity ultrasound stimulation under simulated microgravity.
PloS one , 2013 | Pubmed ID: 24069248
Principal trabecular structural orientation predicted by quantitative ultrasound is strongly correlated with μFEA determined anisotropic apparent stiffness.
Biomechanics and modeling in mechanobiology Oct, 2014 | Pubmed ID: 24419558
Axial transmission method for long bone fracture evaluation by ultrasonic guided waves: simulation, phantom and in vitro experiments.
Ultrasound in medicine & biology Apr, 2014 | Pubmed ID: 24433749
Dynamic fluid flow stimulation on cortical bone and alterations of the gene expressions of osteogenic growth factors and transcription factors in a rat functional disuse model.
Archives of biochemistry and biophysics Mar, 2014 | Pubmed ID: 24486201
Enhancement of cell ingrowth, proliferation, and early differentiation in a three-dimensional silicon carbide scaffold using low-intensity pulsed ultrasound.
Tissue engineering. Part A Jan, 2015 | Pubmed ID: 24935158
Interrelation between external oscillatory muscle coupling amplitude and in vivo intramedullary pressure related bone adaptation.
Bone Sep, 2014 | Pubmed ID: 24947450
Bone tissue engineering: cell motility, vascularization, micro-nano scaffolding, and remodeling.
BioMed research international , 2014 | Pubmed ID: 25210708
Mechanotransduction in musculoskeletal tissue regeneration: effects of fluid flow, loading, and cellular-molecular pathways.
BioMed research international , 2014 | Pubmed ID: 25215295
Effect of low-intensity pulsed ultrasound on biocompatibility and cellular uptake of chitosan-tripolyphosphate nanoparticles.
Biointerphases Sep, 2014 | Pubmed ID: 25280857
Dynamic acoustic radiation force retains bone structural and mechanical integrity in a functional disuse osteopenia model.
Bone Jun, 2015 | Pubmed ID: 25661670
Enhanced correlation between quantitative ultrasound and structural and mechanical properties of bone using combined transmission-reflection measurement.
The Journal of the Acoustical Society of America Mar, 2015 | Pubmed ID: 25786930
Porous three-dimensional carbon nanotube scaffolds for tissue engineering.
Journal of biomedical materials research. Part A Oct, 2015 | Pubmed ID: 25788440
Fabrication and cytocompatibility of in situ crosslinked carbon nanomaterial films.
Scientific reports May, 2015 | Pubmed ID: 26018775
Dynamic fluid flow induced mechanobiological modulation of in situ osteocyte calcium oscillations.
Archives of biochemistry and biophysics Aug, 2015 | Pubmed ID: 26045248
Dynamic Fluid Flow Mechanical Stimulation Modulates Bone Marrow Mesenchymal Stem Cells.
Bone research Mar, 2013 | Pubmed ID: 26273495
Spatial distribution and remodeling of elastic modulus of bone in micro-regime as prediction of early stage osteoporosis.
Journal of biomechanics Jan, 2016 | Pubmed ID: 26705110
Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse.
Bone 06, 2016 | Pubmed ID: 26868528
Erratum to Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse [Bone 87 (2016) 161-168].
Bone 08, 2016 | Pubmed ID: 27262889
Chondro-protective effects of low intensity pulsed ultrasound.
Osteoarthritis and cartilage 11, 2016 | Pubmed ID: 27364595
Novel Spiked-Washer Repair Is Biomechanically Superior to Suture and Bone Tunnels for Arcuate Fracture Repair.
Journal of orthopaedic trauma Mar, 2017 | Pubmed ID: 27984448
Low-Intensity Amplitude Modulated Ultrasound Increases Osteoblastic Mineralization.
Cellular and molecular bioengineering Mar, 2011 | Pubmed ID: 28018491
Comparison of morphological changes of muscle fibers in response to dynamic electrical muscle contraction and dynamic hydraulic stimulation in a rat hindlimb disuse model.
Physiological research 07, 2017 | Pubmed ID: 28248540
In situ examination of osteoblast biomineralization on sulfonated polystyrene-modified substrates using Fourier transform infrared microspectroscopy.
Biointerphases , | Pubmed ID: 28693327
An investigation of shock wave therapy and low-intensity pulsed ultrasound on fracture healing under reduced loading conditions in an ovine model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 03, 2018 | Pubmed ID: 28762588
Effect of capsaicin-sensitive sensory neurons on bone architecture and mechanical properties in the rat hindlimb suspension model.
Journal of orthopaedic translation Jul, 2017 | Pubmed ID: 29662756
Association of reduced sclerostin expression with collapse process in patients with osteonecrosis of the femoral head.
International orthopaedics 07, 2018 | Pubmed ID: 29785591
MC3T3 infiltration and proliferation in bovine trabecular scaffold regulated by dynamic flow bioreactor and augmented by low-intensity pulsed ultrasound.
Journal of orthopaedic translation Jul, 2018 | Pubmed ID: 30035029
Elevated plasma cartilage oligomeric matrix protein (COMP) level are associated with the progression of non-traumatic osteonecrosis of femoral head.
Clinica chimica acta; international journal of clinical chemistry Mar, 2019 | Pubmed ID: 30217750
Acceleration of Bone Defect Healing and Regeneration by Low-Intensity Ultrasound Radiation Force in a Rat Tibial Model.
Ultrasound in medicine & biology 12, 2018 | Pubmed ID: 30286949
Mitigation of Articular Cartilage Degeneration and Subchondral Bone Sclerosis in Osteoarthritis Progression Using Low-Intensity Ultrasound Stimulation.
Ultrasound in medicine & biology 01, 2019 | Pubmed ID: 30322672
Zinc-Based Biomaterials for Regeneration and Therapy.
Trends in biotechnology 04, 2019 | Pubmed ID: 30470548
Retention of osteocytic micromorphology by sclerostin antibody in a concurrent ovariectomy and functional disuse model.
Annals of the New York Academy of Sciences 04, 2019 | Pubmed ID: 30644553
Mechanical Strength, Biodegradation, and in Vitro and in Vivo Biocompatibility of Zn Biomaterials.
ACS applied materials & interfaces Feb, 2019 | Pubmed ID: 30693753
Plasma C-terminal cross-linking telopeptide of type II collagen as a biomarker in advanced stages of femoral head osteonecrosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Mar, 2019 | Pubmed ID: 30841434
Enhanced cytocompatibility and antibacterial property of zinc phosphate coating on biodegradable zinc materials.
Acta biomaterialia 10, 2019 | Pubmed ID: 30930304
A Biomechanical Comparison of Alternative Graft Preparations for All-Inside Anterior Cruciate Ligament Reconstruction.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 05, 2019 | Pubmed ID: 30987907
Biofunctionalization of metallic implants by calcium phosphate coatings.
Bioactive materials Dec, 2019 | Pubmed ID: 31193406
Functional disuse initiates medullary endosteal micro-architectural impairment in cortical bone characterized by nanoindentation.
Journal of bone and mineral metabolism Nov, 2019 | Pubmed ID: 31292723
Engineered nanomedicine for neuroregeneration: light emitting diode-mediated superparamagnetic iron oxide-gold core-shell nanoparticles functionalized by nerve growth factor.
Nanomedicine : nanotechnology, biology, and medicine 10, 2019 | Pubmed ID: 31349088
Interfacial Zinc Phosphate is the Key to Controlling Biocompatibility of Metallic Zinc Implants.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jul, 2019 | Pubmed ID: 31380203
Quantitative ultrasound imaging monitoring progressive disuse osteopenia and mechanical stimulation mitigation in calcaneus region through a 90-day bed rest human study.
Journal of orthopaedic translation Jul, 2019 | Pubmed ID: 31508307
Therapeutic Effects of Low-Intensity Pulsed Ultrasound on Osteoporosis in Ovariectomized Rats: Intensity-Dependent Study.
Ultrasound in medicine & biology 01, 2020 | Pubmed ID: 31587953
Utilization of Finite Element Analysis for Articular Cartilage Tissue Engineering.
Materials (Basel, Switzerland) Oct, 2019 | Pubmed ID: 31614845
Mechanobiological modulation of in situ and in vivo osteocyte calcium oscillation by acoustic radiation force.
Annals of the New York Academy of Sciences 01, 2020 | Pubmed ID: 31646646
Effects of facet joint degeneration on stress alterations in cervical spine C5-C6: A finite element analysis.
Mathematical biosciences and engineering : MBE 08, 2019 | Pubmed ID: 31698622
Evolution of metallic cardiovascular stent materials: A comparative study among stainless steel, magnesium and zinc.
Biomaterials 02, 2020 | Pubmed ID: 31806406
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 11, 2020 | Pubmed ID: 32060941
Porous zinc scaffolds for bone tissue engineering applications: A novel additive manufacturing and casting approach.
Materials science & engineering. C, Materials for biological applications May, 2020 | Pubmed ID: 32204047
Osteoclastic activity was associated with the development of steroid-induced osteonecrosis of femoral head.
Artificial cells, nanomedicine, and biotechnology Dec, 2020 | Pubmed ID: 32667225
Evaluation of nucleus pulposus fluid velocity and pressure alteration induced by cartilage endplate sclerosis using a poro-elastic finite element analysis.
Biomechanics and modeling in mechanobiology Feb, 2021 | Pubmed ID: 32949306
Calcium phosphate coatings enhance biocompatibility and degradation resistance of magnesium alloy: Correlating and studies.
Bioactive materials May, 2021 | Pubmed ID: 33210020
Porous tantalum rod implantation is associated with low survival rates in patients with type C2 osteonecrosis of the femoral head but has no effect on the clinical outcome of conversion total hip arthroplasty: a retrospective study with an average 8-year follow-up.
BMC musculoskeletal disorders Dec, 2020 | Pubmed ID: 33308229
Longitudinal effects of low-intensity pulsed ultrasound on osteoporosis and osteoporotic bone defect in ovariectomized rats.
Ultrasonics May, 2021 | Pubmed ID: 33561635
Piezo1 channel activation in response to mechanobiological acoustic radiation force in osteoblastic cells.
Bone research Mar, 2021 | Pubmed ID: 33692342
Laura Maiorino*,1,2,3,
Margaret Shevik*,1,4,5,
José M. Adrover1,
Xiao Han1,6,
Elias Georgas7,8,
John Erby Wilkinson9,
Harrison Seidner1,
Leonie Foerschner1,
David A. Tuveson1,
Yi-Xian Qin8,
Mikala Egeblad1
1, Cold Spring Harbor Laboratory,
2, Cold Spring Harbor Laboratory School of Biological Sciences,
3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology,
4Medical Scientist Training Program, School of Medicine, Stony Brook University,
5Graduate Program in Pharmacology, Stony Brook University,
6Graduate Program in Genetics, Stony Brook University,
7Graduate Program in Biomedical Engineering, Stony Brook University,
8Department of Biomedical Engineering, Stony Brook University,
9Department of Pathology, University of Michigan
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