Brent Segelke

Structural basis for abrogated binding between staphylococcal enterotoxin A superantigen vaccine and MHC-IIalpha.

The TB structural genomics consortium crystallization facility: towards automation from protein to electron density.

The high-speed Hydra-Plus-One system for automated high-throughput protein crystallography.

Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity.

Laboratory scale structural genomics.

Macromolecular crystallization with microfluidic free-interface diffusion.

Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.

Different apolipoproteins impact nanolipoprotein particle formation.

Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations.

Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles.

Cell-free expression for nanolipoprotein particles: building a high-throughput membrane protein solubility platform.

Atomic force microscopy differentiates discrete size distributions between membrane protein containing and empty nanolipoprotein particles.

Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles.

Characterization and purification of polydisperse reconstituted lipoproteins and nanolipoprotein particles.

Amino acid and structural variability of Yersinia pestis LcrV protein.

An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis.

Structure of Rv1848 (UreA), the Mycobacterium tuberculosis urease gamma subunit.

Isolation, characterization, and stability of discretely-sized nanolipoprotein particles assembled with apolipophorin-III.

Practical applications of structural genomics technologies for mutagen research.

7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source.

Femtosecond X-ray diffraction from two-dimensional protein crystals.

Fixed-target protein serial microcrystallography with an x-ray free electron laser.

Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion.

Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles.

Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals.

Proteomic Profiling of During Host Infection Using Bio-Orthogonal Noncanonical Amino Acid Tagging (BONCAT).

Discovery of Small-Molecule Inhibitors of SARS-CoV-2 Proteins Using a Computational and Experimental Pipeline.

Shotgun Immunoproteomic Approach for the Discovery of Linear B-Cell Epitopes in Biothreat Agents and .

Functional Annotation from Structural Homology.