Cardiovascular Research Unit
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Optimization of diamine bridges in glutaraldehyde treated bioprosthetic aortic wall tissue.
Biomaterials May, 2002 | Pubmed ID: 11962649
Effect of well defined dodecahedral porosity on inflammation and angiogenesis.
ASAIO journal (American Society for Artificial Internal Organs : 1992) Sep-Oct, 2002 | Pubmed ID: 12296563
Bioprosthetic heart valves: the need for a quantum leap.
Biotechnology and applied biochemistry Aug, 2004 | Pubmed ID: 15270708
Carbodiimide treatment dramatically potentiates the anticalcific effect of alpha-amino oleic acid on glutaraldehyde-fixed aortic wall tissue.
The Annals of thoracic surgery Mar, 2005 | Pubmed ID: 15734403
Diamine-extended glutaraldehyde- and carbodiimide crosslinks act synergistically in mitigating bioprosthetic aortic wall calcification.
The Journal of heart valve disease Jul, 2005 | Pubmed ID: 16116882
Bioprosthetic tissue preservation by filling with a poly(acrylamide) hydrogel.
Biomaterials Mar, 2006 | Pubmed ID: 16263164
Prosthetic vascular grafts: wrong models, wrong questions and no healing.
Biomaterials Dec, 2007 | Pubmed ID: 17688939
Prosthetic heart valves: catering for the few.
Biomaterials Feb, 2008 | Pubmed ID: 17950840
A computational study of knitted Nitinol meshes for their prospective use as external vein reinforcement.
Journal of biomechanics , 2008 | Pubmed ID: 18328487
The dosage dependence of VEGF stimulation on scaffold neovascularisation.
Biomaterials Sep, 2008 | Pubmed ID: 18541296
Constrictive external nitinol meshes inhibit vein graft intimal hyperplasia in nonhuman primates.
The Journal of thoracic and cardiovascular surgery Sep, 2008 | Pubmed ID: 18805277
Covalent surface heparinization potentiates porous polyurethane scaffold vascularization.
Journal of biomaterials applications Jan, 2010 | Pubmed ID: 19033329
Utilization of shape memory in external vein-graft meshes allows extreme diameter constriction for suppressing intimal hyperplasia: a non-human primate study.
Journal of vascular surgery Jun, 2009 | Pubmed ID: 19497517
Rapid three-dimensional quantification of VEGF-induced scaffold neovascularisation by microcomputed tomography.
Biomaterials Oct, 2009 | Pubmed ID: 19664820
A synthetic non-degradable polyethylene glycol hydrogel retards adverse post-infarct left ventricular remodeling.
Journal of cardiac failure Sep, 2009 | Pubmed ID: 19700140
The effects of cross-link density and chemistry on the calcification potential of diamine-extended glutaraldehyde-fixed bioprosthetic heart-valve materials.
Biotechnology and applied biochemistry Nov, 2009 | Pubmed ID: 19882764
Tailored sizes of constrictive external vein meshes for coronary artery bypass surgery.
Biomaterials Dec, 2010 | Pubmed ID: 20864157
Induced chronic hypoxia negates the pro-angiogenic effect of surface immobilized heparin in a polyurethane porous scaffold.
Journal of biomedical materials research. Part A Sep, 2011 | Pubmed ID: 21732524
Knitted nitinol represents a new generation of constrictive external vein graft meshes.
Journal of vascular surgery Nov, 2011 | Pubmed ID: 21802240
Sustaining neovascularization of a scaffold through staged release of vascular endothelial growth factor-A and platelet-derived growth factor-BB.
Tissue engineering. Part A Jan, 2012 | Pubmed ID: 21895488
Degradation-induced changes of mechanical properties of an electro-spun polyester-urethane scaffold for soft tissue regeneration.
Journal of biomedical materials research. Part B, Applied biomaterials Nov, 2011 | Pubmed ID: 21948379
The beneficial effects of deferred delivery on the efficiency of hydrogel therapy post myocardial infarction.
Biomaterials Mar, 2012 | Pubmed ID: 22153866
Covalent incorporation and controlled release of active dexamethasone from injectable polyethylene glycol hydrogels.
Journal of biomedical materials research. Part A May, 2013 | Pubmed ID: 23065782
Protective constriction of coronary vein grafts with knitted nitinol.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Jul, 2013 | Pubmed ID: 23295444
Differentiating transmural from transanastomotic prosthetic graft endothelialization through an isolation loop-graft model.
Journal of vascular surgery Oct, 2013 | Pubmed ID: 23541549
Cell specific ingrowth hydrogels.
Biomaterials Sep, 2013 | Pubmed ID: 23777918
A slow-release fibrin matrix increases adeno-associated virus transduction of wound repair cells in vivo.
Journal of biomaterials applications May, 2014 | Pubmed ID: 24163331
Nitric oxide release from polydimethylsiloxane-based polyurethanes.
Journal of applied biomaterials & functional materials Dec, 2014 | Pubmed ID: 24744231
The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models.
Biomaterials Aug, 2014 | Pubmed ID: 24816365
The anisotropic mechanical behaviour of electro-spun biodegradable polymer scaffolds: Experimental characterisation and constitutive formulation.
Journal of the mechanical behavior of biomedical materials Jan, 2016 | Pubmed ID: 26301317
Dual electrospinning with sacrificial fibers for engineered porosity and enhancement of tissue ingrowth.
Journal of biomedical materials research. Part B, Applied biomaterials 08, 2017 | Pubmed ID: 27125901
Cast Tube Assay: A 3-D in vitro assay for visualization and quantification of horizontal chemotaxis and cellular invasion.
BioTechniques , 2016 | Pubmed ID: 27528071
Improved vascularization of porous scaffolds through growth factor delivery from heparinized polyethylene glycol hydrogels.
Acta biomaterialia 02, 2017 | Pubmed ID: 27865963
High heparin content surface-modified polyurethane discs promote rapid and stable angiogenesis in full thickness skin defects through VEGF immobilization.
Journal of biomedical materials research. Part A Sep, 2017 | Pubmed ID: 28509406
Rapidly Recoverable Thixotropic Hydrogels from the Racemate of Chiral OFm Monosubstituted Cyclo(Glu-Glu) Derivatives.
Langmuir : the ACS journal of surfaces and colloids 12, 2017 | Pubmed ID: 29110482
Transmural capillary ingrowth is essential for confluent vascular graft healing.
Acta biomaterialia Jan, 2018 | Pubmed ID: 29111372
Synthetic extracellular matrix mimic hydrogel improves efficacy of mesenchymal stromal cell therapy for ischemic cardiomyopathy.
Acta biomaterialia 04, 2018 | Pubmed ID: 29341932
Transcatheter valve with a hollow balloon for aortic valve insufficiency.
Multimedia manual of cardiothoracic surgery : MMCTS Feb, 2018 | Pubmed ID: 29629555
Suitability of developed composite materials for meniscal replacement: Mechanical, friction and wear evaluation.
Journal of the mechanical behavior of biomedical materials 01, 2019 | Pubmed ID: 30296703
A truly non-occlusive stent-graft moulding balloon for thoracic endovascular aortic repair.
Interactive cardiovascular and thoracic surgery 09, 2019 | Pubmed ID: 30977794
Performance analysis of the transcatheter aortic valve implantation on blood flow hemodynamics: An optical imaging-based in vitro study.
Artificial organs Oct, 2019 | Pubmed ID: 31140632
Preclinical evaluation of a transcatheter aortic valve replacement system for patients with rheumatic heart disease.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Dec, 2019 | Pubmed ID: 31403458
A Preliminary Computational Investigation Into the Flow of PEG in Rat Myocardial Tissue for Regenerative Therapy.
Frontiers in cardiovascular medicine , 2019 | Pubmed ID: 31448288
Customized stent-grafts for endovascular aneurysm repair with challenging necks: A numerical proof of concept.
International journal for numerical methods in biomedical engineering 04, 2020 | Pubmed ID: 32022404
Tissue Ingrowth Markedly Reduces Mechanical Anisotropy and Stiffness in Fibre Direction of Highly Aligned Electrospun Polyurethane Scaffolds.
Cardiovascular engineering and technology 08, 2020 | Pubmed ID: 32613599
Decellularization and engineered crosslinking: a promising dual approach towards bioprosthetic heart valve longevity.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 12, 2020 | Pubmed ID: 32893300
Progressive Reinvention or Destination Lost? Half a Century of Cardiovascular Tissue Engineering.
Frontiers in cardiovascular medicine , 2020 | Pubmed ID: 33033720
Analysis of the regenerative capacity of human serum exosomes after a simple multistep separation from lipoproteins.
Journal of tissue engineering and regenerative medicine 01, 2021 | Pubmed ID: 33175463
Tendon-like tether formation for tongue-base advancement in an ovine model using a novel implant device intended for the surgical management of obstructive sleep apnoea.
Journal of biomedical materials research. Part B, Applied biomaterials 07, 2021 | Pubmed ID: 33283474
Coacervate Delivery of Growth Factors Combined with a Degradable Hydrogel Preserves Heart Function after Myocardial Infarction.
ACS biomaterials science & engineering Sep, 2015 | Pubmed ID: 33445252
TAVR for Patients With Rheumatic Heart Disease: Opening the Door for the Many?
Journal of the American College of Cardiology 04, 2021 | Pubmed ID: 33832597
Long-Term Stability and Biocompatibility of Pericardial Bioprosthetic Heart Valves.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34589529
Residual Bioprosthetic Valve Immunogenicity: Forgotten, Not Lost.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 35059444
The Technological Basis of a Balloon-Expandable TAVR System: Non-occlusive Deployment, Anchorage in the Absence of Calcification and Polymer Leaflets.
Frontiers in cardiovascular medicine , 2022 | Pubmed ID: 35310972
Benedikt Freystetter1,
Maximilian Grab1,2,
Linda Grefen1,
Lara Bischof1,
Lorenz Isert3,
Petra Mela2,
Deon Bezuidenhout4,
Christian Hagl1,5,
Nikolaus Thierfelder1
1Department of Cardiac Surgery, Ludwig Maximilians University Munich,
2Chair of Medical Materials and Implants, Technical University Munich,
3Faculty for Chemistry and Pharmacy, Ludwig Maximilians University Munich,
4Cardiovascular Research Unit, University of Cape Town,
5, DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance
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