Childrens Hospital,
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Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.
Cancer research Jan, 2002 | Pubmed ID: 11809706
A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.
Nature cell biology Feb, 2002 | Pubmed ID: 11812999
A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.
Genes & development Mar, 2002 | Pubmed ID: 11914273
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.
Biotechnology and bioengineering May, 2002 | Pubmed ID: 11948451
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy.
Cell Apr, 2002 | Pubmed ID: 11955443
HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.
Cell Apr, 2002 | Pubmed ID: 11955444
Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336.
Blood Aug, 2002 | Pubmed ID: 12130526
Prospects for stem cell therapeutics: myths and medicines.
Current opinion in genetics & development Oct, 2002 | Pubmed ID: 12200167
Novel retroviral vectors to facilitate expression screens in mammalian cells.
Nucleic acids research Dec, 2002 | Pubmed ID: 12490733
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.
Cell Mar, 2003 | Pubmed ID: 12654249
Dodging the magic bullet: understanding imatinib resistance.
Cancer biology & therapy Jan-Feb, 2003 | Pubmed ID: 12673130
Gleevec resistance: lessons for target-directed drug development.
Cell cycle (Georgetown, Tex.) May-Jun, 2003 | Pubmed ID: 12734421
A role for thrombopoietin in hemangioblast development.
Stem cells (Dayton, Ohio) , 2003 | Pubmed ID: 12743322
Towards combination target-directed chemotherapy for chronic myeloid leukemia: role of farnesyl transferase inhibitors.
Seminars in hematology Apr, 2003 | Pubmed ID: 12783369
From embryos to embryoid bodies: generating blood from embryonic stem cells.
Annals of the New York Academy of Sciences May, 2003 | Pubmed ID: 12799290
ES cells prove egg-straordinary.
Nature biotechnology Jul, 2003 | Pubmed ID: 12833097
Cloning and stem cells--handicapping the political and scientific debates.
The New England journal of medicine Jul, 2003 | Pubmed ID: 12867604
Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 12930895
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes.
Nature Sep, 2003 | Pubmed ID: 13679919
Hematopoiesis from embryonic stem cells: lessons from and for ontogeny.
Experimental hematology Nov, 2003 | Pubmed ID: 14585361
A screen to identify drug resistant variants to target-directed anti-cancer agents.
Biological procedures online , 2003 | Pubmed ID: 14615817
Realistic prospects for stem cell therapeutics.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2003 | Pubmed ID: 14633792
Genetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation.
Oncogene Feb, 2004 | Pubmed ID: 14647454
Derivation of embryonic germ cells and male gametes from embryonic stem cells.
Nature Jan, 2004 | Pubmed ID: 14668819
Mechanisms and implications of imatinib resistance mutations in BCR-ABL.
Current opinion in hematology Jan, 2004 | Pubmed ID: 14676625
Development of hematopoietic repopulating cells from embryonic stem cells.
Methods in enzymology , 2003 | Pubmed ID: 14696341
小鼠胚胎干细胞自我更新与分化信号转导多元蛋白质组学分析。
Proceedings of the National Academy of Sciences of the United States of America Mar, 2004 | Pubmed ID: 14978270
Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.
Journal of neuroscience research Apr, 2004 | Pubmed ID: 15048913
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.
Oncogene Jun, 2004 | Pubmed ID: 15064711
Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models.
Current topics in developmental biology , 2004 | Pubmed ID: 15094298
Nuclear transplantation, embryonic stem cells and the potential for cell therapy.
The hematology journal : the official journal of the European Haematology Association / EHA , 2004 | Pubmed ID: 15190291
Alchemy in the liver: fact or fusion?
Nature medicine Jul, 2004 | Pubmed ID: 15229507
Missed opportunities in embryonic stem-cell research.
The New England journal of medicine Aug, 2004 | Pubmed ID: 15302910
LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells.
Stem cells (Dayton, Ohio) , 2004 | Pubmed ID: 15342941
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions.
Bioinformatics (Oxford, England) Mar, 2005 | Pubmed ID: 15479714
Inducible transgene expression in mouse stem cells.
Methods in molecular medicine , 2005 | Pubmed ID: 15492386
Chronic myeloid leukemia: proving ground for cancer stem cells.
Cell Oct, 2004 | Pubmed ID: 15507204
In vitro gametogenesis from embryonic stem cells.
Current opinion in cell biology Dec, 2004 | Pubmed ID: 15530782
Altered nuclear transfer in stem-cell research - a flawed proposal.
The New England journal of medicine Dec, 2004 | Pubmed ID: 15625329
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.
Cancer cell Feb, 2005 | Pubmed ID: 15710326
The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation.
Blood Jun, 2005 | Pubmed ID: 15728128
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.
Oncogene May, 2005 | Pubmed ID: 15735728
High-efficiency RNA interference in human embryonic stem cells.
Stem cells (Dayton, Ohio) Mar, 2005 | Pubmed ID: 15749924
Stem cell research: science, ethics and policy.
Medical ethics (Burlington, Mass.) , 2005 | Pubmed ID: 15856604
Customized human embryonic stem cells.
Nature biotechnology Jul, 2005 | Pubmed ID: 16003368
Patterning definitive hematopoietic stem cells from embryonic stem cells.
Experimental hematology Sep, 2005 | Pubmed ID: 16140144
Therapeutic potential of embryonic stem cells.
Blood reviews Nov, 2005 | Pubmed ID: 16275420
Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells.
Blood Apr, 2006 | Pubmed ID: 16332966
Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy.
Cancer Jan, 2006 | Pubmed ID: 16342165
Novel role for PDEF in epithelial cell migration and invasion.
Cancer research Dec, 2005 | Pubmed ID: 16357167
Embryonic stem cell-derived hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2005 | Pubmed ID: 16357205
Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor.
Blood Apr, 2006 | Pubmed ID: 16403910
Anticipating clinical resistance to target-directed agents : the BCR-ABL paradigm.
Molecular diagnosis & therapy , 2006 | Pubmed ID: 16669605
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2006 | Pubmed ID: 16754879
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2006 | Pubmed ID: 17068127
Male germ cells.
Methods in enzymology , 2006 | Pubmed ID: 17141043
Transgene expression and RNA interference in embryonic stem cells.
Methods in enzymology , 2006 | Pubmed ID: 17161693
Histocompatible embryonic stem cells by parthenogenesis.
Science (New York, N.Y.) Jan, 2007 | Pubmed ID: 17170255
Ethics. The ISSCR guidelines for human embryonic stem cell research.
Science (New York, N.Y.) Feb, 2007 | Pubmed ID: 17272706
The cdx-hox pathway in hematopoietic stem cell formation from embryonic stem cells.
Annals of the New York Academy of Sciences Jun, 2007 | Pubmed ID: 17303828
Differentiation potential of histocompatible parthenogenetic embryonic stem cells.
Annals of the New York Academy of Sciences Jun, 2007 | Pubmed ID: 17360798
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.
Blood Jul, 2007 | Pubmed ID: 17392504
Gametes from embryonic stem cells: a cup half empty or half full?
Science (New York, N.Y.) Apr, 2007 | Pubmed ID: 17446394
In vitro generation of germ cells from murine embryonic stem cells.
Nature protocols , 2006 | Pubmed ID: 17487192
Towards hematopoietic reconstitution from embryonic stem cells: a sanguine future.
Current opinion in hematology Jul, 2007 | Pubmed ID: 17534159
Farnesyl transferase inhibitor resistance probed by target mutagenesis.
Blood Sep, 2007 | Pubmed ID: 17536018
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.
Nature Jun, 2007 | Pubmed ID: 17581586
Human embryonic stem cells flock together.
Nature biotechnology Jul, 2007 | Pubmed ID: 17621300
Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single-agent therapy with imatinib.
Cancer Sep, 2007 | Pubmed ID: 17623836
Hemogenic endothelial progenitor cells isolated from human umbilical cord blood.
Stem cells (Dayton, Ohio) Nov, 2007 | Pubmed ID: 17641248
Debugging cellular reprogramming.
Nature cell biology Aug, 2007 | Pubmed ID: 17671453
Current prospects for the generation of patient-specific pluripotent cells from adult tissues.
Regenerative medicine Sep, 2007 | Pubmed ID: 17907926
Towards the generation of patient-specific pluripotent stem cells for combined gene and cell therapy of hematologic disorders.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2007 | Pubmed ID: 18024604
Reprogramming of human somatic cells to pluripotency with defined factors.
Nature Jan, 2008 | Pubmed ID: 18157115
Human embryonic stem cell derivation from poor-quality embryos.
Nature biotechnology Feb, 2008 | Pubmed ID: 18223642
Enhanced plating efficiency of trypsin-adapted human embryonic stem cells is reversible and independent of trisomy 12/17.
Cloning and stem cells Mar, 2008 | Pubmed ID: 18241122
Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes.
Blood May, 2008 | Pubmed ID: 18252864
Selective blockade of microRNA processing by Lin28.
Science (New York, N.Y.) Apr, 2008 | Pubmed ID: 18292307
Prospects for stem cell-based therapy.
Cell Feb, 2008 | Pubmed ID: 18295571
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome.
The Journal of clinical investigation Apr, 2008 | Pubmed ID: 18324336
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera.
Cell stem cell Sep, 2007 | Pubmed ID: 18371359
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer.
Cell stem cell Sep, 2007 | Pubmed ID: 18371368
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.
Cell stem cell Jan, 2008 | Pubmed ID: 18371423
Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos.
Nature protocols , 2008 | Pubmed ID: 18451800
Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2008 | Pubmed ID: 18511567
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos.
Nature genetics Jul, 2008 | Pubmed ID: 18536715
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18550544
Generation of human-induced pluripotent stem cells.
Nature protocols , 2008 | Pubmed ID: 18600223
Molecular basis of pluripotency.
Human molecular genetics Apr, 2008 | Pubmed ID: 18632692
From fibroblasts to iPS cells: induced pluripotency by defined factors.
Journal of cellular biochemistry Nov, 2008 | Pubmed ID: 18668528
Disease-specific induced pluripotent stem cells.
Cell Sep, 2008 | Pubmed ID: 18691744
Isolation of hematopoietic stem cells from mouse embryonic stem cells.
Current protocols in stem cell biology Feb, 2008 | Pubmed ID: 18770632
Activation of tyrosine kinases by mutation of the gatekeeper threonine.
Nature structural & molecular biology Oct, 2008 | Pubmed ID: 18794843
Mesodermal patterning activity of SCL.
Experimental hematology Dec, 2008 | Pubmed ID: 18809240
New ISSCR guidelines underscore major principles for responsible translational stem cell research.
Cell stem cell Dec, 2008 | Pubmed ID: 19041777
Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19089348
Human iPS cell derivation/reprogramming.
Current protocols in stem cell biology Jan, 2009 | Pubmed ID: 19170021
ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines.
Blood Apr, 2009 | Pubmed ID: 19171873
Broader implications of defining standards for the pluripotency of iPSCs.
Cell stem cell Mar, 2009 | Pubmed ID: 19265657
Generation of induced pluripotent stem cells from human blood.
Blood May, 2009 | Pubmed ID: 19299331
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration.
Cell Mar, 2009 | Pubmed ID: 19303855
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.
Nature biotechnology Apr, 2009 | Pubmed ID: 19329998
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming.
Nature biotechnology Apr, 2009 | Pubmed ID: 19330000
Upping the ante: recent advances in direct reprogramming.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2009 | Pubmed ID: 19337233
Functional evidence that the self-renewal gene NANOG regulates human tumor development.
Stem cells (Dayton, Ohio) May, 2009 | Pubmed ID: 19415763
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells.
Blood Jul, 2009 | Pubmed ID: 19420357
Biomechanical forces promote embryonic haematopoiesis.
Nature Jun, 2009 | Pubmed ID: 19440194
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
Nature Jun, 2009 | Pubmed ID: 19458618
Lin28 promotes transformation and is associated with advanced human malignancies.
Nature genetics Jul, 2009 | Pubmed ID: 19483683
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment.
Nature Jul, 2009 | Pubmed ID: 19516257
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.
Cell stem cell Jul, 2009 | Pubmed ID: 19540188
Balancing work and life: a conversation with George Daley. Interviewed by Majlinda Lako and Susan Daher.
Stem cells (Dayton, Ohio) Jul, 2009 | Pubmed ID: 19544404
Cross-regulation of the Nanog and Cdx2 promoters.
Cell research Sep, 2009 | Pubmed ID: 19564890
9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.
Journal of medicinal chemistry Aug, 2009 | Pubmed ID: 19572547
A role for Lin28 in primordial germ-cell development and germ-cell malignancy.
Nature Aug, 2009 | Pubmed ID: 19578360
microRNA expression during trophectoderm specification.
PloS one , 2009 | Pubmed ID: 19582159
Disease models from pluripotent stem cells.
Annals of the New York Academy of Sciences Sep, 2009 | Pubmed ID: 19796247
Hematopoietic development from human induced pluripotent stem cells.
Annals of the New York Academy of Sciences Sep, 2009 | Pubmed ID: 19796250
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.
Nature biotechnology Nov, 2009 | Pubmed ID: 19826408
Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
Hepatology (Baltimore, Md.) Jan, 2010 | Pubmed ID: 19877180
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts.
Nature genetics Dec, 2009 | Pubmed ID: 19881528
Autologous blood cell therapies from pluripotent stem cells.
Blood reviews Jan, 2010 | Pubmed ID: 19910091
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.
PLoS genetics Nov, 2009 | Pubmed ID: 19911041
Application of induced pluripotent stem cells to hematologic disease.
Cytotherapy , 2009 | Pubmed ID: 19929461
AP24163 inhibits the gatekeeper mutant of BCR-ABL and suppresses in vitro resistance.
Chemical biology & drug design Feb, 2010 | Pubmed ID: 20028401
Stem cells: roadmap to the clinic.
The Journal of clinical investigation Jan, 2010 | Pubmed ID: 20051631
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature Jan, 2010 | Pubmed ID: 20072125
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.
Blood Apr, 2010 | Pubmed ID: 20089964
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients.
Nature Mar, 2010 | Pubmed ID: 20164838
Lin28: A microRNA regulator with a macro role.
Cell Feb, 2010 | Pubmed ID: 20178735
AID for reprogramming.
Cell research Mar, 2010 | Pubmed ID: 20190775
Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity.
Stem cell reviews Jun, 2010 | Pubmed ID: 20376579
Interaction of retinoic acid and scl controls primitive blood development.
Blood Jul, 2010 | Pubmed ID: 20410509
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells.
Cell stem cell May, 2010 | Pubmed ID: 20452313
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis.
Haematologica Oct, 2010 | Pubmed ID: 20494928
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies.
Nature genetics Jul, 2010 | Pubmed ID: 20512147
Straight talk with...George Daley. Interview by Elie Dolgin.
Nature medicine Jun, 2010 | Pubmed ID: 20526308
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.
Nature medicine Aug, 2010 | Pubmed ID: 20616797
Reprogramming of T cells from human peripheral blood.
Cell stem cell Jul, 2010 | Pubmed ID: 20621044
Molecular basis of the first cell fate determination in mouse embryogenesis.
Cell research Sep, 2010 | Pubmed ID: 20628366
All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.
PloS one , 2010 | Pubmed ID: 20644631
Comprehensive methylome map of lineage commitment from haematopoietic progenitors.
Nature Sep, 2010 | Pubmed ID: 20720541
Clump passaging and expansion of human embryonic and induced pluripotent stem cells on mouse embryonic fibroblast feeder cells.
Current protocols in stem cell biology Aug, 2010 | Pubmed ID: 20814935
Dynamic instability of genomic methylation patterns in pluripotent stem cells.
Epigenetics & chromatin , 2010 | Pubmed ID: 20868487
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.
Cell stem cell Nov, 2010 | Pubmed ID: 20888316
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
Blood Jan, 2011 | Pubmed ID: 21037085
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.
Nature genetics Dec, 2010 | Pubmed ID: 21057500
Another horse in the meta-stable state of pluripotency.
Cell stem cell Dec, 2010 | Pubmed ID: 21112555
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states.
Cell stem cell Dec, 2010 | Pubmed ID: 21112562
Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies.
The Journal of allergy and clinical immunology Jun, 2011 | Pubmed ID: 21185069
Cellular therapy for fanconi anemia: the past, present, and future.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Jan, 2011 | Pubmed ID: 21195298
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.
Development (Cambridge, England) Mar, 2011 | Pubmed ID: 21270052
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Cell stem cell Feb, 2011 | Pubmed ID: 21295276
Somatic coding mutations in human induced pluripotent stem cells.
Nature Mar, 2011 | Pubmed ID: 21368825
Investigating monogenic and complex diseases with pluripotent stem cells.
Nature reviews. Genetics Apr, 2011 | Pubmed ID: 21386866
Interactions between Cdx genes and retinoic acid modulate early cardiogenesis.
Developmental biology Jun, 2011 | Pubmed ID: 21466798
Induced pluripotent stem cells for neural tissue engineering.
Biomaterials Aug, 2011 | Pubmed ID: 21514663
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
Nature May, 2011 | Pubmed ID: 21552279
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.
PloS one , 2011 | Pubmed ID: 21559507
The nomenclature system should be sustainable, but also practical.
Cell stem cell Jun, 2011 | Pubmed ID: 21624802
microRNAs become macro players in somatic cell reprogramming.
Genome medicine , 2011 | Pubmed ID: 21699744
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.
Annals of neurology Sep, 2011 | Pubmed ID: 21721033
Induced pluripotent stem cells for modelling human diseases.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Aug, 2011 | Pubmed ID: 21727133
From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond.
Genes & cancer Dec, 2010 | Pubmed ID: 21779439
Telomere dynamics in dyskeratosis congenita: the long and the short of iPS.
Cell research Aug, 2011 | Pubmed ID: 21788988
Genomic approaches to deconstruct pluripotency.
Annual review of genomics and human genetics Sep, 2011 | Pubmed ID: 21801025
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.
Cell Aug, 2011 | Pubmed ID: 21854985
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity.
Nature cell biology Oct, 2011 | Pubmed ID: 21909099
The Lin28/let-7 axis regulates glucose metabolism.
Cell Sep, 2011 | Pubmed ID: 21962509
Stem cells: Triple genomes go far.
Nature Oct, 2011 | Pubmed ID: 21979039
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration.
Cell Oct, 2011 | Pubmed ID: 22036566
Induced pluripotent stem cells--opportunities for disease modelling and drug discovery.
Nature reviews. Drug discovery Dec, 2011 | Pubmed ID: 22076509
Cell cycle adaptations of embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22084091
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells.
Nature biotechnology Dec, 2011 | Pubmed ID: 22119740
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nature biotechnology Dec, 2011 | Pubmed ID: 22119741
Live-cell immunofluorescence staining of human pluripotent stem cells.
Current protocols in stem cell biology Dec, 2011 | Pubmed ID: 22135082
Polycomb repressive complex 2 regulates normal development of the mouse heart.
Circulation research Feb, 2012 | Pubmed ID: 22158708
The promise of induced pluripotent stem cells in research and therapy.
Nature Jan, 2012 | Pubmed ID: 22258608
Derivation of human embryonic stem cells with NEMO deficiency.
Stem cell research Jan, 2012 | Pubmed ID: 22284529
Overcoming Reprogramming Resistance of Fanconi Anemia Cells.
Blood Feb, 2012 | Pubmed ID: 22371882
Chromatin-modifying enzymes as modulators of reprogramming.
Nature Mar, 2012 | Pubmed ID: 22388813
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway.
Developmental cell Mar, 2012 | Pubmed ID: 22421047
Reprogramming cellular identity for regenerative medicine.
Cell Mar, 2012 | Pubmed ID: 22424223
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22451909
Accessing naïve human pluripotency.
Current opinion in genetics & development Jun, 2012 | Pubmed ID: 22463982
Pluripotent stem cells in research and treatment of hemoglobinopathies.
Cold Spring Harbor perspectives in medicine Apr, 2012 | Pubmed ID: 22474618
Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA.
Current protocols in stem cell biology , 2012 | Pubmed ID: 22605648
Neuronal properties, in vivo effects, and pathology of a Huntington's disease patient-derived induced pluripotent stem cells.
Stem cells (Dayton, Ohio) Sep, 2012 | Pubmed ID: 22628015
Stem cells assessed.
Nature reviews. Molecular cell biology Jul, 2012 | Pubmed ID: 22678486
Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient.
The Biochemical journal Sep, 2012 | Pubmed ID: 22694310
The promise and perils of stem cell therapeutics.
Cell stem cell Jun, 2012 | Pubmed ID: 22704514
New lessons learned from disease modeling with induced pluripotent stem cells.
Current opinion in genetics & development Oct, 2012 | Pubmed ID: 22749051
Caudal genes in blood development and leukemia.
Annals of the New York Academy of Sciences Aug, 2012 | Pubmed ID: 22901255
Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates.
Cardiovascular research Dec, 2012 | Pubmed ID: 22941255
Therapeutic potential of human induced pluripotent stem cells in experimental stroke.
Cell transplantation , 2013 | Pubmed ID: 23044029
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23045682
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions.
BMC genomics , 2012 | Pubmed ID: 23102236
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
Nature Oct, 2012 | Pubmed ID: 23103873
Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
Science (New York, N.Y.) Jan, 2013 | Pubmed ID: 23118012
Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal.
Cell stem cell Nov, 2012 | Pubmed ID: 23122286
The transcriptional landscape of hematopoietic stem cell ontogeny.
Cell stem cell Nov, 2012 | Pubmed ID: 23122293
Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival.
PLoS genetics , 2012 | Pubmed ID: 23209448
Cellular alchemy and the golden age of reprogramming.
Cell Dec, 2012 | Pubmed ID: 23217698
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2013 | Pubmed ID: 23236128
A blueprint for engineering cell fate: current technologies to reprogram cell identity.
Cell research Jan, 2013 | Pubmed ID: 23277278
Reprogrammed cells for disease modeling and regenerative medicine.
Annual review of medicine , 2013 | Pubmed ID: 23327523
Lin28a Regulates Germ Cell Pool Size and Fertility.
Stem cells (Dayton, Ohio) Feb, 2013 | Pubmed ID: 23378032
Induced pluripotent stem cells with a mitochondrial DNA deletion.
Stem cells (Dayton, Ohio) Jul, 2013 | Pubmed ID: 23400930
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity.
Experimental cell research Jul, 2013 | Pubmed ID: 23528453
Lin28: primal regulator of growth and metabolism in stem cells.
Cell stem cell Apr, 2013 | Pubmed ID: 23561442
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.
Cell stem cell Jun, 2013 | Pubmed ID: 23602541
Deciphering the rules of ceRNA networks.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23620514
Regulation of stem cell therapies under attack in Europe: for whom the bell tolls.
The EMBO journal May, 2013 | Pubmed ID: 23644381
Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism.
Stem cells (Dayton, Ohio) Aug, 2013 | Pubmed ID: 23666760
Origins and implications of pluripotent stem cell variability and heterogeneity.
Nature reviews. Molecular cell biology Jun, 2013 | Pubmed ID: 23673969
Stem cell metabolism in tissue development and aging.
Development (Cambridge, England) Jun, 2013 | Pubmed ID: 23715547
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.
Blood Aug, 2013 | Pubmed ID: 23733337
Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".
Science translational medicine Jun, 2013 | Pubmed ID: 23740897
A new route to human embryonic stem cells.
Nature medicine Jul, 2013 | Pubmed ID: 23836223
Optimization of scarless human stem cell genome editing.
Nucleic acids research Jul, 2013 | Pubmed ID: 23907390
A chemical logic for reprogramming to pluripotency.
Cell research Dec, 2013 | Pubmed ID: 23979017
Stem cells: Reprogramming in situ.
Nature Oct, 2013 | Pubmed ID: 24025771
Hematopoietic defects and iPSC disease modeling: lessons learned.
Immunology letters Sep-Oct, 2013 | Pubmed ID: 24076116
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
Cell stem cell Oct, 2013 | Pubmed ID: 24094326
Proteolytic autodigestion: common tissue pathology in Shwachman-Diamond syndrome?
Cell cycle (Georgetown, Tex.) , 2013 | Pubmed ID: 24107623
Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells.
Retrovirology , 2013 | Pubmed ID: 24156636
Development. A stem cell perspective on cellular engineering.
Science (New York, N.Y.) Nov, 2013 | Pubmed ID: 24202165
Lin28 enhances tissue repair by reprogramming cellular metabolism.
Cell Nov, 2013 | Pubmed ID: 24209617
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.
Molecular cell Jan, 2014 | Pubmed ID: 24361252
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.
The Journal of experimental medicine Jan, 2014 | Pubmed ID: 24395885
Lin28 sustains early renal progenitors and induces Wilms tumor.
Genes & development May, 2014 | Pubmed ID: 24732380
Functional evaluation of ES-somatic cell hybrids in vitro and in vivo.
Cellular reprogramming Jun, 2014 | Pubmed ID: 24787484
Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells.
Cell stem cell Jul, 2014 | Pubmed ID: 24813856
Effect of developmental stage of HSC and recipient on transplant outcomes.
Developmental cell Jun, 2014 | Pubmed ID: 24914562
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
Cancer cell Aug, 2014 | Pubmed ID: 25117712
Dissecting engineered cell types and enhancing cell fate conversion via CellNet.
Cell Aug, 2014 | Pubmed ID: 25126792
CellNet: network biology applied to stem cell engineering.
Cell Aug, 2014 | Pubmed ID: 25126793
Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease.
Science (New York, N.Y.) Aug, 2014 | Pubmed ID: 25146295
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming.
Stem cell reports Nov, 2014 | Pubmed ID: 25316190
A nontranscriptional role for Oct4 in the regulation of mitotic entry.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25324523
A comparison of non-integrating reprogramming methods.
Nature biotechnology Jan, 2015 | Pubmed ID: 25437882
Deriving blood stem cells from pluripotent stem cells for research and therapy.
Best practice & research. Clinical haematology Sep-Dec, 2014 | Pubmed ID: 25455281
Deconstructing transcriptional heterogeneity in pluripotent stem cells.
Nature Dec, 2014 | Pubmed ID: 25471879
Defining cellular identity through network biology.
Cell cycle (Georgetown, Tex.) , 2014 | Pubmed ID: 25485572
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.
Blood Feb, 2015 | Pubmed ID: 25587036
Metabolic switches linked to pluripotency and embryonic stem cell differentiation.
Cell metabolism Mar, 2015 | Pubmed ID: 25738450
De novo generation of HSCs from somatic and pluripotent stem cell sources.
Blood Mar, 2015 | Pubmed ID: 25762177
Biotechnology. A prudent path forward for genomic engineering and germline gene modification.
Science (New York, N.Y.) Apr, 2015 | Pubmed ID: 25791083
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