Jineng Lv

Identification of a novel GJA8 (Cx50) point mutation causes human dominant congenital cataracts.

AAV-mediated lysophosphatidylcholine acyltransferase 1 (Lpcat1) gene replacement therapy rescues retinal degeneration in rd11 mice.

SLC7A14 linked to autosomal recessive retinitis pigmentosa.

Identification of false-negative mutations missed by next-generation sequencing in retinitis pigmentosa patients: a complementary approach to clinical genetic diagnostic testing.

Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.

miR-183/96 plays a pivotal regulatory role in mouse photoreceptor maturation and maintenance.

Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients.

Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome.

Nonhuman Primate Model of Oculocutaneous Albinism with and Mutations.

Generation of Nonhuman Primate Model of Cone Dysfunction through AAV-Mediated Ablation.

Engineered FnCas12a with enhanced activity through directional evolution in human cells.

Human cell based directed evolution of adenine base editors with improved efficiency.

Two high-fidelity variants: efSaCas9 and SaCas9-HF, which one is better?

Depletion of miR-96 Delays, But Does Not Arrest, Photoreceptor Development in Mice.

Can SpRY recognize any PAM in human cells?

Identification of RPGR ORF15 mutation for X-linked retinitis pigmentosa in a large Chinese family and in vitro correction with prime editor.

A precise and efficient adenine base editor.