Laboratory of Malaria and Vector Research,
National Institute of Allergy and Infectious Diseases,
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases
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A novel secreted endonuclease from Culex quinquefasciatus salivary glands.
The Journal of experimental biology Jul, 2006 | Pubmed ID: 16809456
An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti.
BMC genomics Jan, 2007 | Pubmed ID: 17204158
An insight into the sialome of Anopheles funestus reveals an emerging pattern in anopheline salivary protein families.
Insect biochemistry and molecular biology Feb, 2007 | Pubmed ID: 17244545
Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factor.
The Journal of biological chemistry Sep, 2007 | Pubmed ID: 17650501
The crystal structure of D7r4, a salivary biogenic amine-binding protein from the malaria mosquito Anopheles gambiae.
The Journal of biological chemistry Dec, 2007 | Pubmed ID: 17928288
Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite.
Protein science : a publication of the Protein Society Jan, 2008 | Pubmed ID: 18042685
Cutting edge: Immunity against a "silent" salivary antigen of the Lyme vector Ixodes scapularis impairs its ability to feed.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18832673
The salivary gland transcriptome of the neotropical malaria vector Anopheles darlingi reveals accelerated evolution of genes relevant to hematophagy.
BMC genomics Jan, 2009 | Pubmed ID: 19178717
Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19234127
An insight into the sialotranscriptome of the West Nile mosquito vector, Culex tarsalis.
BMC genomics , 2010 | Pubmed ID: 20089177
The salivary gland transcriptome of the eastern tree hole mosquito, Ochlerotatus triseriatus.
Journal of medical entomology May, 2010 | Pubmed ID: 20496585
The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
PLoS biology Nov, 2010 | Pubmed ID: 21152418
Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
The Journal of biological chemistry Aug, 2011 | Pubmed ID: 21673107
An insight into the sialome of Simulium guianense (DIPTERA:SIMulIIDAE), the main vector of River Blindness Disease in Brazil.
BMC genomics Dec, 2011 | Pubmed ID: 22182526
Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells.
Blood Mar, 2012 | Pubmed ID: 22302738
Tick salivary secretion as a source of antihemostatics.
Journal of proteomics Jul, 2012 | Pubmed ID: 22564820
Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder.
PloS one , 2013 | Pubmed ID: 23658744
Effects of Aedes aegypti salivary components on dendritic cell and lymphocyte biology.
Parasites & vectors Nov, 2013 | Pubmed ID: 24238038
A deep insight into the sialotranscriptome of the mosquito, Psorophora albipes.
BMC genomics Dec, 2013 | Pubmed ID: 24330624
Lundep, a sand fly salivary endonuclease increases Leishmania parasite survival in neutrophils and inhibits XIIa contact activation in human plasma.
PLoS pathogens Feb, 2014 | Pubmed ID: 24516388
Simplagrin, a platelet aggregation inhibitor from Simulium nigrimanum salivary glands specifically binds to the Von Willebrand factor receptor in collagen and inhibits carotid thrombus formation in vivo.
PLoS neglected tropical diseases Jun, 2014 | Pubmed ID: 24921659
Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes.
Parasites & vectors May, 2015 | Pubmed ID: 25975355
A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae.
Nature communications Jun, 2015 | Pubmed ID: 26100162
The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.
Infection and immunity Jun, 2016 | Pubmed ID: 27045038
Immunity to LuloHya and Lundep, the salivary spreading factors from Lutzomyia longipalpis, protects against Leishmania major infection.
PLoS pathogens May, 2018 | Pubmed ID: 29723281
Antibody targeting of a specific region of blocks malaria transmission.
NPJ vaccines , 2018 | Pubmed ID: 30002917
Optimization of sand fly embryo microinjection for gene editing by CRISPR/Cas9.
PLoS neglected tropical diseases 09, 2018 | Pubmed ID: 30180160
The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin.
Cellular and molecular life sciences : CMLS May, 2019 | Pubmed ID: 30747251
Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles.
Cell Apr, 2019 | Pubmed ID: 30929905
evades immunity of anopheline mosquitoes by interacting with a Pfs47 midgut receptor.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2020 | Pubmed ID: 31969456
ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals.
Nature communications Jun, 2020 | Pubmed ID: 32518308
Biochemical characterization of AeD7L2 and its physiological relevance in blood feeding in the dengue mosquito vector, Aedes aegypti.
The FEBS journal Mar, 2021 | Pubmed ID: 32799410
D7 Salivary Protein Prevents Host Hemostasis and Inflammation.
Biomolecules Sep, 2020 | Pubmed ID: 32992542
Inflammasome Fuels Dengue Severity.
Frontiers in cellular and infection microbiology , 2020 | Pubmed ID: 33014899
RNA-sequencing of the Nyssomyia neivai sialome: a sand fly-vector from a Brazilian endemic area for tegumentary leishmaniasis and pemphigus foliaceus.
Scientific reports Oct, 2020 | Pubmed ID: 33077743
Aedes aegypti SGS1 is critical for Plasmodium gallinaceum infection of both the mosquito midgut and salivary glands.
Malaria journal Jan, 2021 | Pubmed ID: 33407511
The structures of two salivary proteins from the West Nile vector reveal a beta-trefoil fold with putative sugar binding properties.
Current research in structural biology , 2021 | Pubmed ID: 34235489
Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus.
Acta crystallographica. Section D, Structural biology Sep, 2021 | Pubmed ID: 34473088
Arboviruses: How Saliva Impacts the Journey from Vector to Host.
International journal of molecular sciences Aug, 2021 | Pubmed ID: 34502092
Piwi4 Structural Features Are Necessary for RNA Binding and Nuclear Localization.
International journal of molecular sciences Nov, 2021 | Pubmed ID: 34884537
Multiple Salivary Proteins from Mosquito Bind to the Zika Virus Envelope Protein.
Viruses Jan, 2022 | Pubmed ID: 35215815
Aedes aegypti sialokinin facilitates mosquito blood feeding and modulates host immunity and vascular biology.
Cell reports Apr, 2022 | Pubmed ID: 35417706
Novel salivary antihemostatic activities of long-form D7 proteins from the malaria vector Anopheles gambiae facilitate hematophagy.
The Journal of biological chemistry Jun, 2022 | Pubmed ID: 35460690
Alboserpin, the Main Salivary Anticoagulant from the Disease Vector , Displays Anti-FXa-PAR Signaling In Vitro and In Vivo.
ImmunoHorizons Jun, 2022 | Pubmed ID: 35738824
Performing Immunohistochemistry in Mosquito Salivary Glands.
Cold Spring Harbor protocols Oct, 2022 | Pubmed ID: 35960615
A Simple Method for Immunohistochemistry and Imaging of Mosquito Salivary Glands.
Cold Spring Harbor protocols Oct, 2022 | Pubmed ID: 35960629
An insight into the female and male Sabethes cyaneus mosquito salivary glands transcriptome.
Insect biochemistry and molecular biology Feb, 2023 | Pubmed ID: 36587808
Determination of Mosquito Probing and Feeding Time to Evaluate Mosquito Blood Feeding.
Cold Spring Harbor protocols Jun, 2023 | Pubmed ID: 36669861
Evaluation of Feeding Status.
Cold Spring Harbor protocols Jun, 2023 | Pubmed ID: 36690389
Evaluation of Penetration, Probing, and Feeding Times on Mice.
Cold Spring Harbor protocols Jun, 2023 | Pubmed ID: 36690390
Native structure of mosquito salivary protein uncovers domains relevant to pathogen transmission.
Nature communications Feb, 2023 | Pubmed ID: 36797290
The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites.
PLoS pathogens Mar, 2023 | Pubmed ID: 36862755
salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission.
bioRxiv : the preprint server for biology May, 2023 | Pubmed ID: 37292610
Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae.
Nature communications Jul, 2023 | Pubmed ID: 37463914
Guianensin, a salivary protein, has broad anti-hemostatic and anti-inflammatory properties.
Frontiers in immunology , 2023 | Pubmed ID: 37469515
Adeline E. Williams1,2,
Irma Sanchez-Vargas1,
Lindsay E. Martin2,3,
Ines Martin-Martin2,4,
Susi Bennett1,
Ken E. Olson1,
Eric Calvo2
1Center for Vector-borne Infectious Diseases, Department of Microbiology, Immunology, and Pathology, Colorado State University,
2Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health,
3Department of Biological Sciences, Vanderbilt University,
4National Center for Microbiology, Instituto de Salud Carlos III
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