Department of Molecular Medicine and Pathology,
School of Medical Sciences,
Centre for Brain Research,
Department of Molecular Medicine and Pathology, School of Medical Sciences
E. Scott Graham has not added Biography.
If you are E. Scott Graham and would like to personalize this page please email our Author Liaison for assistance.
Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.
The Journal of biological chemistry Sep, 2006 | Pubmed ID: 16864584
Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!
Journal of neuroscience methods Jun, 2008 | Pubmed ID: 18406468
Cannabinoid Receptors: A brief history and what not.
Frontiers in bioscience (Landmark edition) Jan, 2009 | Pubmed ID: 19273110
Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry.
International journal of immunopathology and pharmacology , 2010 | Pubmed ID: 20377992
Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics.
Biochemical pharmacology Oct, 2010 | Pubmed ID: 20599795
Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology.
Journal of neuroscience methods Sep, 2011 | Pubmed ID: 21781988
Detailed analysis of inflammatory and neuromodulatory cytokine secretion from human NT2 astrocytes using multiplex bead array.
Neurochemistry international May, 2012 | Pubmed ID: 21939706
Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay.
Journal of biomolecular screening Mar, 2012 | Pubmed ID: 22140120
M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells.
PloS one , 2013 | Pubmed ID: 24023725
Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF.
PloS one , 2013 | Pubmed ID: 24339874
A Cell Derived Active Contour (CDAC) method for robust tracking in low frame rate, low contrast phase microscopy - an example: the human hNT astrocyte.
PloS one , 2013 | Pubmed ID: 24358233
Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation.
PloS one , 2013 | Pubmed ID: 24367648
Enrichment of differentiated hNT neurons and subsequent analysis using flow-cytometry and xCELLigence sensing.
Journal of neuroscience methods Apr, 2014 | Pubmed ID: 24530700
Development of positive control tissue for in situ hybridisation using Alvetex scaffolds.
Journal of neuroscience methods Dec, 2014 | Pubmed ID: 25244955
Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time.
Biosensors Apr, 2015 | Pubmed ID: 25893878
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells.
Journal of neuroinflammation Jul, 2015 | Pubmed ID: 26152369
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors.
Scientific reports Jan, 2016 | Pubmed ID: 26813587
TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function.
Journal of neuroinflammation Feb, 2016 | Pubmed ID: 26867675
Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression.
Scientific reports 05, 2016 | Pubmed ID: 27215737
Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21.
Immunology and cell biology Nov, 2016 | Pubmed ID: 27301418
Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier.
PloS one , 2016 | Pubmed ID: 27309956
Interferon-γ blocks signalling through PDGFRβ in human brain pericytes.
Journal of neuroinflammation Sep, 2016 | Pubmed ID: 27654972
ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα.
PloS one , 2017 | Pubmed ID: 28732059
Is the Cannabinoid CB Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans?
Advances in pharmacology (San Diego, Calif.) , 2017 | Pubmed ID: 28826541
Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products.
Biosensors Sep, 2017 | Pubmed ID: 28934106
The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release.
Biochimica et biophysica acta. General subjects Mar, 2018 | Pubmed ID: 29158134
The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier.
Biosensors Jul, 2018 | Pubmed ID: 29973526
The functional and inflammatory response of brain endothelial cells to Toll-Like Receptor agonists.
Scientific reports Jul, 2018 | Pubmed ID: 29973684
In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology.
Biosensors Oct, 2018 | Pubmed ID: 30314393
Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology.
Biosensors Apr, 2019 | Pubmed ID: 30991758
Evaluation of parylene derivatives for use as biomaterials for human astrocyte cell patterning.
PloS one , 2019 | Pubmed ID: 31237927
Large 10 × 10 single cell grid networks of human hNT astrocytes on raised parylene-C/SiO substrates.
Journal of neural engineering Oct, 2019 | Pubmed ID: 31394515
Bradykinin receptor-1 activation induces inflammation and increases the permeability of human brain microvascular endothelial cells.
Cell biology international Sep, 2019 | Pubmed ID: 31498530
Cannabinoid Receptor 2 (CB) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes.
ACS pharmacology & translational science Dec, 2019 | Pubmed ID: 32259074
Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells.
International journal of molecular sciences Nov, 2020 | Pubmed ID: 33139674
Geometric micro-shapes facilitate trackless connections between human astrocytes.
Journal of neural engineering Apr, 2021 | Pubmed ID: 33601342
Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time.
Biosensors May, 2021 | Pubmed ID: 34069959
Superior galvanostatic electrochemical deposition of platinum nanograss provides high performance planar microelectrodes forneural recording.
Journal of neural engineering Aug, 2021 | Pubmed ID: 34371484
Can ECIS Biosensor Technology Be Used to Measure the Cellular Responses of Glioblastoma Stem Cells?
Biosensors Dec, 2021 | Pubmed ID: 34940255
Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis.
BMC neurology Jun, 2022 | Pubmed ID: 35690735
Critical Spatial-Temporal Dynamics and Prominent Shape Collapse of Calcium Waves Observed in Human hNT Astrocytes .
Frontiers in physiology , 2022 | Pubmed ID: 35784870
Comprehensive Assessment of Secreted Immuno-Modulatory Cytokines by Serum-Differentiated and Stem-like Glioblastoma Cells Reveals Distinct Differences between Glioblastoma Phenotypes.
International journal of molecular sciences Nov, 2022 | Pubmed ID: 36430641
Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins.
International journal of molecular sciences Mar, 2023 | Pubmed ID: 37047054
The interaction of placental micro-EVs with immune cells in vivo and in vitro.
American journal of reproductive immunology (New York, N.Y. : 1989) Sep, 2023 | Pubmed ID: 37641368
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유