social-defeat-stress-model-for-adolescent-c57bl6-male-and-female-mice

Social Defeat Stress Model for Adolescent C57BL&#47;6 Male and Female Mice

Social adversity in adolescence is prevalent and can negatively impact mental health trajectories. Modeling social stress in adolescent male and female ...

McGill University

Adolescence is a unique period of psychosocial growth during which social adversity can negatively influence mental health trajectories. Understanding how adolescent social stress impacts males and females and why some individuals are particularly affected is becoming increasingly urgent. Social defeat stress models for adolescent male mice have been effective in reproducing some physical/psychological aspects of bullying. Designing a model suitable for females has proven challenging.

Samuel Richer

Integrated Program in Neuroscience

McGill University

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice