Department of Chemistry and Applied Biosciences
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A microfluidic vesicle screening platform: monitoring the lipid membrane permeability of tetracyclines.
Analytical chemistry Dec, 2011 | Pubmed ID: 22010628
A microchamber array for single cell isolation and analysis of intracellular biomolecules.
Lab on a chip Feb, 2012 | Pubmed ID: 22183159
A new mechanobiological era: microfluidic pathways to apply and sense forces at the cellular level.
Current opinion in chemical biology Aug, 2012 | Pubmed ID: 22525494
A facile protocol for the immobilisation of vesicles, virus particles, bacteria, and yeast cells.
Integrative biology : quantitative biosciences from nano to macro Dec, 2012 | Pubmed ID: 23147942
Interfacing droplet microfluidics with matrix-assisted laser desorption/ionization mass spectrometry: label-free content analysis of single droplets.
Analytical chemistry Feb, 2013 | Pubmed ID: 23289755
Full spectroscopic tip-enhanced Raman imaging of single nanotapes formed from β-amyloid(1-40) peptide fragments.
ACS nano Feb, 2013 | Pubmed ID: 23311496
Enantiomeric and diastereoisomeric (mixed) L/ D-octaarginine derivatives - a simple way of modulating the properties of cell-penetrating peptides.
Chemistry & biodiversity Jul, 2013 | Pubmed ID: 23847063
On-chip enzyme quantification of single Escherichia coli bacteria by immunoassay-based analysis.
Analytical chemistry Dec, 2014 | Pubmed ID: 25409480
A liposomal fluorescence assay to study permeation kinetics of drug-like weak bases across the lipid bilayer.
Journal of controlled release : official journal of the Controlled Release Society Jan, 2014 | Pubmed ID: 24211703
Quantification of saquinavir from lysates of peripheral blood mononuclear cells using microarrays and standard MALDI-TOF-MS.
Journal of the American Society for Mass Spectrometry Jun, 2014 | Pubmed ID: 24711229
Cell-free microfluidic determination of P-glycoprotein interactions with substrates and inhibitors.
Pharmaceutical research Dec, 2014 | Pubmed ID: 24928366
Interaction of β(3) /β(2) -peptides, consisting of Val-Ala-Leu segments, with POPC giant unilamellar vesicles (GUVs) and white blood cancer cells (U937)--a new type of cell-penetrating peptides, and a surprising chain-length dependence of their vesicle- and cell-lysing activity.
Chemistry & biodiversity May, 2015 | Pubmed ID: 26010661
Differential Isotope Labeling of Glycopeptides for Accurate Determination of Differences in Site-Specific Glycosylation.
Journal of proteome research Jan, 2016 | Pubmed ID: 26573365
Detection of Infertility-related Neutralizing Antibodies with a Cell-free Microfluidic Method.
Scientific reports , 2015 | Pubmed ID: 26585778
A microfluidic device for the delivery of enzymes into cells by liposome fusion.
Engineering in life sciences Feb, 2018 | Pubmed ID: 29416447
In vitro quantification of botulinum neurotoxin type A1 using immobilized nerve cell-mimicking nanoreactors in a microfluidic platform.
The Analyst Sep, 2019 | Pubmed ID: 31433410
Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection.
Cell reports Jan, 2020 | Pubmed ID: 31995768
High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics.
Nature biotechnology Jun, 2020 | Pubmed ID: 32231335
Author Correction: High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics.
Nature biotechnology Jun, 2020 | Pubmed ID: 32444853
Quantitative modeling of the effect of antigen dosage on B-cell affinity distributions in maturating germinal centers.
eLife Jun, 2020 | Pubmed ID: 32538783
The impact of frost-damage on the quality and quantity of the secreted antigen-specific IgG repertoire.
Vaccine Jul, 2020 | Pubmed ID: 32571724
The Quantitative Assessment of the Secreted IgG Repertoire after Recall to Evaluate the Quality of Immunizations.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2020 | Pubmed ID: 32669311
Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap.
Nature protocols Sep, 2020 | Pubmed ID: 32788719
One by One - Insights into Complex Immune Responses through Functional Single-cell Analysis.
Chimia Sep, 2020 | Pubmed ID: 32958110
Deep phenotypic characterization of immunization-induced antibacterial IgG repertoires in mice using a single-antibody bioassay.
Communications biology Oct, 2020 | Pubmed ID: 33106526
Author Correction: Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap.
Nature protocols Aug, 2021 | Pubmed ID: 33442054
Measuring single-cell protein secretion in immunology: Technologies, advances, and applications.
European journal of immunology Jun, 2021 | Pubmed ID: 33734428
An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip.
Scientific reports 08, 2021 | Pubmed ID: 34429486
High-affinity autoreactive plasma cells disseminate through multiple organs in patients with immune thrombocytopenic purpura.
The Journal of clinical investigation Jun, 2022 | Pubmed ID: 35503254
Insights into the relationship between persistent antibody secretion and metabolic programming - A question for single-cell analysis.
Immunology letters Aug, 2023 | Pubmed ID: 37315849
Single-cell deep phenotyping of cytokine release unmasks stimulation-specific biological signatures and distinct secretion dynamics.
Cell reports methods Jul, 2023 | Pubmed ID: 37533643
Antibodies, repertoires and microdevices in antibody discovery and characterization.
Lab on a chip Feb, 2024 | Pubmed ID: 38165819
Aline Linder*,1,
Kevin Portmann*,1,
Luca Johannes Schlotheuber1,
Alessandro Streuli1,
Wiona Sophie Glänzer1,
Klaus Eyer1,2,
Ines Lüchtefeld1,3
1Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich,
2Department of Biomedicine, Aarhus University,
3Laboratory for Tumor and Stem Cell Dynamics, Institute of Molecular Health Sciences, Department of Biology, ETH Zürich
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