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Key Laboratory of Livestock and Poultry Multi-omics of MARA

1 ARTICLES PUBLISHED IN JoVE

Environment

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Ming Hu¹, Zhengjie Liu^1,2, Ziang Song^1,3, Lulu Li¹, Xiaonan Zhao¹, Yanbo Luo¹, Qing Zhang¹, Yibao Chen¹, Xiaohui Xu¹, Yahui Dong¹, Nataliia Hrabchenko¹, Wei Zhang³, Yuqing Liu¹

¹Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, P.R. China, Key Laboratory of Livestock and Poultry Multi-omics of MARA, ²Department of Genetic and Genomes Biology, University of Leicester, ³College of Veterinary Medicine, Nanjing Agricultural University

Here we introduce the principle, structure, and instruction of the intelligent high-throughput antimicrobial sensitivity testing/phage screening system. Its application is illustrated by using Salmonella isolated from poultry in Shandong, China, as an example. The Lar index is calculated, and its significance in evaluating antimicrobial resistance is discussed comprehensively.