This protocol describes in vitro cultivation of the syphilis pathogen Treponema pallidum subsp. pallidum in co-culture with mammalian cells. The method is scalable; it can be used to produce large quantities of T. pallidum and to generate clonal cultures.

procedures-for-vitro-cultivation-treponema-pallidum-syphilis

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete

For over a century, Treponema pallidum subsp. pallidum, the spiral-shaped bacterium that causes syphilis, could only be propagated by inoculation and ...

University of Texas Health Science Center at Houston - McGovern Medical School

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