PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRPHongshuai Li 1,2, Bingyun Li 1,3,4
1Department of Orthopaedics, School of Medicine, West Virginia University , 2Department of Orthopaedics, Stem Cell Research Center, University of Pittsburgh, 3WVNano Initiative, 4Mary Babb Randolph Cancer Center
Implant-associated infection is a significant clinical complication. This study describes an approach using platelet-rich plasma (PRP) to prevent implant-associated infections, presents the protocol for preparing PRP with constant platelet concentration, and reports the newly identified antimicrobial properties of PRP and related protocols for examining such antimicrobial properties in vitro.
