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Beijing Institute of Precision Mechatronics and Controls

4 ARTICLES PUBLISHED IN JoVE

Engineering

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Jonathan A. Kopechek¹, Peng Zhang¹, Mark T. Burgess¹, Tyrone M. Porter¹

¹Department of Mechanical Engineering, Boston University

Phase-shift nanoemulsions (PSNE) can be vaporized using high intensity focused ultrasound to enhance localized heating and improve thermal ablation in tumors. In this report, the preparation of stable PSNE with a narrow size distribution is described. Furthermore, the impact of vaporized PSNE on ultrasound-mediated ablation is demonstrated in tissue-mimicking phantoms.

Biology

Partial Bile Duct Ligation in the Mouse: A Controlled Model of Localized Obstructive Cholestasis

Shinichiro Yokota^1,2, Yoshihiro Ono², Toshimasa Nakao², Peng Zhang³, George K. Michalopoulos^4,5, Zahida Khan^3,4,5,6

¹Department of Surgery, Jichi Medical University, ²Department of Surgery, University of Pittsburgh School of Medicine, ³Department of Pediatrics, University of Pittsburgh School of Medicine, ⁴Department of Pathology, University of Pittsburgh School of Medicine, ⁵Pittsburgh Liver Research Center, University of Pittsburgh, ⁶McGowan Institute for Regenerative Medicine, University of Pittsburgh

Here, we present partial bile duct ligation as a surgical model of liver injury and regeneration in rodents.

Genetics

Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens

Jinxia Shi¹, Yijuan Jia¹, Di Fang¹, Shidan He¹, Peng Zhang^1,2, Yushuang Guo³, Yongli Qiao¹

¹Shanghai Key Laboratory of Plant Molecular Sciences, College of Life Sciences, Shanghai Normal University, ²College of Agriculture, Yangtze University, ³Laboratory of Molecular Genetics, China National Tobacco Corporation, Guizhou Institute of Tobacco Science

Here, we present a modified screening method that can be extensively used to quickly screen RNA silencing suppressors in plant pathogens.

Education

A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump

Xu Han¹, Peng Zhang², Tatiana Minav³, Yongling Fu¹, Jian Fu¹

¹School of Mechanical Engineering and Automation, Beihang University, ²Beijing Institute of Precision Mechatronics and Controls, ³Innovative Hydraulics and Automation, Tampere University

A simulation model specifically supporting the preliminary design of an electro-variable displacement pump (EVDP) is developed and partially verified by experiments. The control performance, life, reliability, etc., can all be evaluated using the proposed model, which covers the main performance requirements under the EVDP preliminary design task.