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University of Insubria

4 ARTICLES PUBLISHED IN JoVE

Biology

Laparoscopic Left Liver Sectoriectomy of Caroli's Disease Limited to Segment II and III

Luigi Boni¹, Gianlorenzo Dionigi², Francesca Rovera¹, Matteo Di Giuseppe¹

¹Minimally Invasive Surgery Resarch Center, Department of Surgical Sciences, University of Insubria, ²Endocrine Surgery Research Center, University of Insubria

This video presents a case of laparoscopic left liver sectoriectomy perfomed in a 53 year old man suffering from Caroli's disease limited to segment II and III of the liver.

Cancer Research

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Giovanni Micheloni^*1, Giorgia Millefanti^*1, Andrea Conti¹, Cristina Pirrone¹, Alessandro Marando², Alessia Rainero¹, Lucia Tararà¹, Andrea Pistochini³, Francesco Lo Curto¹, Francesco Pasquali¹, Paolo Castelnuovo³, Francesco Acquati³, Annalisa Grimaldi³, Roberto Valli¹, Giovanni Porta¹

¹Department of Medicine and Surgery, University of Insubria, ²Department of Surgical and Morphological Science, University of Insubria, ³Department of Biotechnology and Life Science, University of Insubria

Homeobox genes are regulatory genes often associated with tumors in the adult organisms. We investigated their comparative expression by immunohistochemical and real-time PCR analysis, in normal and inflammatory nasal mucosae and in sinonasal neoplasms in order to use them as possible diagnostic and therapeutic targets.

Medicine

Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model

Che-Wei Wu^1,2,3, Tzu-Yen Huang², Hui-Chun Chen⁴, Hsiu-Ya Chen⁵, Tsung-Yi Tsai², Pi-Ying Chang⁵, Yi-Chu Lin², Hsin-Yi Tseng², Pao-Chu Hun⁶, Xiaoli Liu⁷, Hui Sun⁷, Gregory W. Randolph⁸, Gianlorenzo Dionigi⁹, Feng-Yu Chiang^2,3, I-Cheng Lu^5,10,11

This study aims to develop a standard protocol of intra-operative neural monitoring of thyroid surgery in a porcine model. Here, we present a protocol to demonstrate general anesthesia, to compare different types of electrodes, and to investigate the electrophysiological characteristics of the normal and injured recurrent laryngeal nerves.

Medicine

Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model

Hsin-Yi Tseng¹, Tzu-Yen Huang¹, Jia Joanna Wang^1,2, Yi-Chu Lin¹, I-Cheng Lu³, Feng-Yu Chiang⁴, Gianlorenzo Dionigi^5,6, Gregory W. Randolph⁷, Che-Wei Wu^1,8

¹Department of Otorhinolaryngology-Head and Neck Surgery, International Thyroid Surgery Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, ²Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, ³Department of Anesthesiology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, ⁴Department of Otolaryngology-Head and Neck Surgery, E-Da Hospital, I-Shou University, ⁵Division of General Surgery, Endocrine Surgery Section, Istituto Auxologico Italiano (IRCCS), ⁶Department of Pathophysiology and Transplantation, Faculty of Medicine and Surgery, University of Milan, ⁷Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, ⁸Center for Liquid Biopsy and Cohort Research, and Faculty of Medicine, College of Medicine, Kaohsiung Medical University

The safe application of newly developed surgical energy devices in thyroid/parathyroid surgery attracts the attention of surgeons. Animal experimental models can avoid unnecessary trials and errors in human surgery. This report aims to demonstrate electrophysiological and thermographic methods to evaluate the safety parameters of SEDs in thyroid/parathyroid surgery.