A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein InteractionsMandy Muller *1,2, Patricia Cassonnet *1, Michel Favre 1, Yves Jacob 1,3, Caroline Demeret 1
1Unité de Génétique, Papillomavirus et Cancer Humain (GPCH), Institut Pasteur , 2Cellule Pasteur, Université Sorbonne Paris Cité, 3Center for Cancer Systems Biology (CCSB), Harvard Medical School, Department of Cancer Biology, Dana Farber Cancer Institute
This article focuses on the identification of high-confident interaction datasets between host and pathogen proteins using a combination of two orthogonal methods: yeast two-hybrid followed by a high-throughput interaction assay in mammalian cells called HT-GPCA.
