An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor TissuesChristopher Terranova 1, Ming Tang 1, Elias Orouji 1, Mayinuer Maitituoheti 1, Ayush Raman 1, Samirkumar Amin 2, Zhiyi Liu 1, Kunal Rai 1
1Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, 2The Jackson Laboratory for Genomic Medicine
Here, we describe an optimized high-throughput ChIP-sequencing protocol and computational analyses pipeline for the determination of genome-wide chromatin state patterns from frozen tumor tissues and cell lines.
