Mouse Model of Pressure Ulcers After Spinal Cord InjurySuneel Kumar 1, Yuying Tan 1, Martin L. Yarmush 1,2, Biraja C. Dash 3, Henry C. Hsia 3, Francois Berthiaume 1
1Department of Biomedical Engineering, Rutgers University, 2Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, 3Department of Surgery, Yale School of Medicine, Yale University
Here, we describe a simple method to induce clinically relevant skin pressure ulcers (PUs) in a mouse model of spinal cord injury (SCI). This model can be used in pre-clinical studies to screen for different therapeutics for healing PUs in SCI patients.
