The tau aggregation assay described in this manuscript mimics the anticipated features of in vivo tau misfolding and aggregation.
Here we describe a cell-based assay to quantitatively assess tau uptake by microglia with the aim of creating an investigational tool to better characterize the mechanisms of action of anti-tau antibodies.
The BSelex method to identify and recover individual antigen-specific antibodies from human peripheral blood mononuclear cells combines flow cytometry with single cell PCR and cloning.
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유