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Alpert Brown Medical School

2 ARTICLES PUBLISHED IN JoVE

Medicine

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Noah S. Philip¹, S. Louisa Carpenter¹, Lawrence H. Sweet²

¹Providence VA Medical Center, Department of Psychiatry & Human Behavior, Alpert Medical School, Brown University, ²Department of Psychology, University of Georgia

This protocol describes the complementary neuroimaging techniques of resting state structural connectivity, task-induced deactivation, and structural connectivity analyses to examine the default network in post-traumatic stress disorder. The use of synergistic methods could potentially lead to improved diagnostics and assessments of severity, outcome, and other relevant clinical factors.

Neuroscience

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure

Mascha van 't Wout-Frank^1,2,3, Noah S. Philip^1,2,3

¹VA RR&D Center for Neurorestoration and Neurotechnology, Providence VA Medical Healthcare System, ²Department of Psychiatry and Human Behavior, Alpert Brown Medical School, ³COBRE Center for Neuromodulation, Butler Hospital

This manuscript outlines a novel protocol to allow the simultaneous application of transcranial direct current stimulation during exposure to warzone trauma-related cues using virtual reality for veterans with posttraumatic stress disorder.