Longitudinal Follow-Up of Urinary Tract Infections and Their Treatment in Mice using Bioluminescence ImagingNoémie Luyts 1, Greetje Vande Velde 2, Matthias Vanneste 1, Helene De Bruyn 1, Annelies Janssens 1, Natalie Verstraeten 3, Thomas Voets 1, Wouter Everaerts 4
1Laboratory of Ion Channel Research (LICR), VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium & Department of Cellular and Molecular Medicine, KU Leuven, 2Biomedical MRI, Department of Imaging & Pathology, KU Leuven, 3Belgium & KU Leuven Centre of Microbial and Plant Genetics, VIB-KU Leuven Center for Microbiology, Leuven, 4Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven
This manuscript describes the intravesical administration of uropathogenic bacteria with a lux operon to induce a urinary tract infection in mice and subsequent longitudinal in vivo analysis of the bacterial load using bioluminescence imaging.
